Related references
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Article
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Summary: The study found a significant increase in GDM prevalence during the COVID-19 pandemic compared to 2019, especially in 5/6 months of the final semester in 2020. Logistic regression analysis also indicated a temporal relationship between experiencing lockdown in the first trimester of pregnancy and later GDM incidence.
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(2022)
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Nando Reza Pratama et al.
Summary: Objective Pregnancy is a known risk factor for severe COVID-19, and it is important to develop safe vaccines for pregnant women. This study reviewed the existing research on COVID-19 vaccination in pregnancy and found that mRNA-based vaccines can prevent SARS-CoV-2 infection without clear harm to pregnancy. The most common adverse reactions were transient and included pain at the injection site, fatigue, and headache. Antibody responses were rapid and strengthened with booster doses. Longer intervals between vaccination and delivery were associated with higher antibody levels in the baby. The study concludes that mRNA vaccines are encouraged for pregnant women, and two doses are recommended for better maternal and fetal antibody responses.
Article
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Mihaela Uta et al.
Summary: Anemia is common during pregnancy, and it is considered a risk factor for severity and negative outcomes in patients with SARS-CoV-2 infection. A study was conducted to determine the impact of nutritional supplementation for iron deficiency anemia in correlation with SARS-CoV-2 infection. The results showed that iron deficiency anemia was significantly higher in pregnant women with COVID-19 and was associated with low birth weight, prematurity, and lower APGAR scores. Nutritional supplementation with iron and folate during pregnancy was found to normalize birth weight. It is important to screen for iron and folate deficiency in pregnant women at risk and supplement their nutritional intake to promote normal development and avoid complications during the COVID-19 pandemic.
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Michael Wilkinson et al.
Summary: There is conflicting evidence regarding the effect of COVID-19 in pregnancy. This study found no significant impact of COVID-19 on birth outcomes, such as stillbirth, neonatal death, and birthweight. However, symptomatic COVID-19 was associated with a higher risk of preterm birth, possibly due to an increase in iatrogenic deliveries for maternal indications.
SCIENTIFIC REPORTS
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Iosif Marincu et al.
Summary: This paper summarizes a case-control study conducted in Romania, which explores the advantages of vaccination for individuals previously infected with SARS-CoV-2. The results indicate that vaccination provides longer protection than natural immunity, and reduces hospitalization duration and the need for oxygen supplementation after reinfection.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
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Medicine, General & Internal
Ramasamy Sathiya et al.
Summary: COVID-19 and preeclampsia share similar medical features, making it difficult to differentiate them in pregnant women. Early diagnosis of preeclampsia can be achieved by detecting angiogenic markers, which helps avoid unnecessary interventions and induced preterm labor.
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Summary: The study found that infection with SARS-CoV-2 during pregnancy increases the risk of early miscarriage.
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Meghana A. Limaye et al.
Summary: The study aimed to determine factors associated with severe/critical COVID-19 disease in pregnant women. Results showed a significant association between severe/critical disease and a history of smoking, COVID-19 diagnosis in the 2nd trimester, asthma or other respiratory conditions, cesarean delivery, and preterm delivery.
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Ioana Mihaela Citu et al.
Summary: Magnesium may contribute to the immune response during and after SARS-CoV-2 infection. Taking magnesium-based nutritional supplements during pregnancy could lead to higher levels of SARS-CoV-2 anti-RBD antibodies. Low magnesium dosage was identified as an independent risk factor for a weak immune response.
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Roxana Margan et al.
Summary: Around 20% of couples worldwide are affected by infertility issues, with numbers in the European Union reaching as high as 25%. This research focuses on the unique challenges faced by Romanian couples seeking assisted reproductive therapy (ART). The study found that high stress levels were associated with longer duration to achieve pregnancy using ART. Couples with a monthly household income higher than EUR 1000 and undergoing more expensive ART methods had a significantly higher chance of achieving pregnancy. Advanced age, high stress levels, and the high cost of ART were negatively associated with successful pregnancy using ART. These findings highlight the financial burden and stress experienced by Romanian couples dealing with infertility, impacting their chances of conception.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
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Medicine, General & Internal
Ioana Mihaela Citu et al.
Summary: Clinical trials initially excluded pregnant women from COVID-19 vaccination, but observational studies found that pregnant women infected with COVID-19 had higher risks of negative pregnancy outcomes. Research showed that the risk of spontaneous abortion after mRNA COVID-19 immunization during the first trimester of pregnancy is comparable to the predicted risk in non-vaccinated pregnant women.
JOURNAL OF CLINICAL MEDICINE
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Obstetrics & Gynecology
Zeliha Atak et al.
Summary: This study aims to demonstrate the poor prognosis of unvaccinated pregnant women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The results show an increase in maternal mortality and stillbirth rates associated with COVID-19 infection, and the clinical and laboratory parameters are found to be associated with mortality.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
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Noga Fallach et al.
Summary: This study aimed to assess the risk of preterm birth (PTB) and small-for-gestational-age (SGA) in women infected with SARS-CoV-2 during early trimesters. The results showed that the risk of PTB increased in women infected during late pregnancy, particularly after 34 weeks of gestation. Symptomatic infected women had a higher risk of PTB in the third trimester.
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Immunology
Cosmin Citu et al.
Summary: This study investigated the acceptance of COVID-19 vaccination among pregnant women in Romania and identified factors influencing their choices. The findings revealed that factors such as urban residence, higher education, the third trimester of pregnancy, trust in the government, frequent travel, concern about the severity of COVID-19, availability of vaccines nearby, and observing others getting vaccinated were significantly associated with vaccination acceptance.
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Medicine, General & Internal
Estera Boeriu et al.
Summary: Infectious diseases are a significant concern for pediatric cancer patients, particularly those experiencing fever and neutropenia. This review analyzes the latest literature on therapeutic strategies and efficacy for pediatric patients with febrile neutropenia. It highlights the importance of prompt administration of empiric broad-spectrum antibiotics and the need for improved identification of underlying causes.
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Medical Informatics
Samantha N. Piekos et al.
Summary: The study evaluated the impact of maternal SARS-CoV-2 infection on birth outcomes and developed models to predict gestational age at delivery following an infection during pregnancy. Results showed an increased risk of preterm delivery and stillbirth, primarily associated with first and second trimester infections. Monitoring and prenatal care are recommended for pregnant individuals after SARS-CoV-2 infection in early pregnancy, regardless of COVID-19 severity.
LANCET DIGITAL HEALTH
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Obstetrics & Gynecology
Alexander M. Kotlyar et al.
Summary: The study found that 3.2% of 936 neonates from mothers with coronavirus disease 2019 tested positive for severe acute respiratory syndrome coronavirus 2 viral RNA using nasopharyngeal swab. The rates of infection are similar to those of other pathogens causing congenital infections but further research is needed to determine the rates of vertical transmission in early pregnancy and potential risk for fetal morbidity and mortality.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
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Obstetrics & Gynecology
Justin S. Brandt et al.
Summary: This study aimed to quantify the associations of coronavirus disease 2019 with adverse maternal and neonatal outcomes in pregnancy, showing that the disease is associated with an increased risk of adverse maternal and neonatal outcomes, primarily driven by morbidity associated with severe or critical coronavirus disease 2019. Major risk factors for associated morbidity were identified as black and Hispanic race, obesity, advanced maternal age, medical comorbidities, and antepartum admissions related to coronavirus disease 2019.
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Cinzia Auriti et al.
Summary: Viral infections during pregnancy can present risks to the fetus or newborn, with asymptomatic infants potentially experiencing worse outcomes at birth and potential long-term neurosensory issues. Maternal immune system adaptations during pregnancy play a crucial role in maintaining a balance between maternal immunity and fetal health, with viral infections disrupting this balance and leading to adverse outcomes for the fetus and newborn.
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Calin Jianu et al.
Summary: The study evaluated the antioxidant and antimicrobial activities of Nepeta x faassenii essential oil for the first time, identifying major compounds like nepetalactone and elemol. The oil demonstrated strong scavenging and antioxidative activity in various assays, outperforming BHA in inhibiting lipid oxidation. The results suggest that this essential oil may serve as a potential antioxidant and antimicrobial agent in medicine or the food industry.
APPLIED SCIENCES-BASEL
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Immunology
Francesca Crovetto et al.
Summary: This study found that pregnancy complications in women with SARS-CoV-2 infection were similar to those of noninfected women overall, but symptomatic COVID-19 was associated with modest increases in preterm delivery and intrapartum fetal distress.
CLINICAL INFECTIOUS DISEASES
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OBSTETRICS AND GYNECOLOGY
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Sylvie Epelboin et al.
Summary: During the first wave of the COVID-19 pandemic, pregnant women with COVID-19 diagnosis showed higher frequencies of maternal morbidities and adverse obstetrical outcomes compared to pregnant women without COVID-19 diagnosis, highlighting the importance of awareness and care for this population.
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Medicine, General & Internal
Shu Qin Wei et al.
Summary: Infection with COVID-19 during pregnancy may lead to an increased risk of preeclampsia, preterm birth, and other adverse pregnancy outcomes. Severe cases of COVID-19 are particularly associated with higher risks of complications such as preeclampsia, preterm birth, gestational diabetes, and low birth weight.
CANADIAN MEDICAL ASSOCIATION JOURNAL
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Immunology
Jean Y. Ko et al.
Summary: This study explored the association between COVID-19 at delivery and adverse pregnancy outcomes, finding increased risks for several severe complications. Discharge status was not affected by COVID-19 diagnosis, and there were no significant differences in risk for complications or severe illness by race/ethnicity.
CLINICAL INFECTIOUS DISEASES
(2021)
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Medicine, General & Internal
Cosmin Citu et al.
Summary: A prospective study on pregnant women with COVID-19 found that these women faced higher risks during pregnancy, but their newborns generally did not have negative outcomes except for prematurity, with a minimal number being infected. This supports the idea of maintaining maternal-newborn contact during delivery, as they do not seem to have an increased risk of SARS-CoV-2 infection.
JOURNAL OF CLINICAL MEDICINE
(2021)
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Medicine, General & Internal
Mikael Norman et al.
Summary: In a nationwide cohort of infants in Sweden, maternal SARS-CoV-2 infection in pregnancy was significantly associated with small increases in some neonatal morbidities. Given the small numbers of events for many of the outcomes and the large number of statistical comparisons, the findings should be interpreted as exploratory.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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Obstetrics & Gynecology
Vanessa L. Jacoby et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
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Laura E. Riley
NEW ENGLAND JOURNAL OF MEDICINE
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Ishaan Chaubey et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
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Immunology
Habib Sadeghi Rad et al.
Summary: Maternal infection with COVID-19 may disrupt placental function and lead to pregnancy-related complications such as miscarriage, restricted fetal growth, or stillbirth. Most newborns test negative following delivery, suggesting protective mechanisms within the placenta.
FRONTIERS IN IMMUNOLOGY
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Review
Infectious Diseases
Feng Guo et al.
Summary: In pregnant women, COVID-19 infection poses a higher risk of developing into severe illness, with increased likelihood of ICU admission and intubation. Diagnosis through chest CT and blood tests is essential for quick identification, and multidisciplinary consultation is recommended for treatment policy. The safety, efficacy, and immunity of approved vaccines for mothers and infants, as well as the mechanism of virus transmission in placental tissues, require further investigation.
INFECTION AND DRUG RESISTANCE
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Madalina Timircan et al.
Summary: The study found that unemployed pregnant women living in poverty in rural areas were more likely to be infected with SARS-CoV-2 during pregnancy, and faced higher levels of anxiety and depression. Interestingly, COVID-19 facilities had significantly lower technical competence scores.
MEDICINA-LITHUANIA
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Public, Environmental & Occupational Health
Samy Zaky et al.
Summary: The study examined the impact of COVID-19 on pregnant women and found no significant differences between pregnant and non-pregnant women in the main outcomes of the disease. The need for mechanical ventilation and mortality rates also did not show significant differences between the two groups.
JOURNAL OF THE EGYPTIAN PUBLIC HEALTH ASSOCIATION
(2021)
Article
Medicine, General & Internal
Madalina Timircan et al.
Summary: This study reveals that a third-trimester infection with SARS-CoV-2 significantly increases the risk of premature rupture of membranes, preterm birth with emergency c-sections, and lower APGAR scores in newborns. Pregnancies where mothers are infected with SARS-CoV-2 are more likely to have premature births and lower APGAR scores in newborns.
MEDICINA-LITHUANIA
(2021)
Review
Medicine, General & Internal
Chiu-Lin Wang et al.
Summary: COVID-19, caused by SARS-CoV-2, is an emerging disease that has rapidly spread worldwide since its identification in Wuhan, China, in December 2019. Limited data on the clinical characteristics of pregnant women with COVID-19 have been reported, raising concerns about their risk of infection and clinical outcomes.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
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M. Mendoza et al.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
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Gillian A. Ryean et al.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
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Antonio La Marca et al.
REPRODUCTIVE BIOMEDICINE ONLINE
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Pilar Diaz-Corvillon et al.
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