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Cancer Stem Cell Relationship with Pro-Tumoral Inflammatory Microenvironment

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Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications

Eunice Yuen-Ting Lau et al.

STEM CELLS INTERNATIONAL (2017)

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Anti-CD47 Antibody As a Targeted Therapeutic Agent for Human Lung Cancer and Cancer Stem Cells

Liang Liu et al.

FRONTIERS IN IMMUNOLOGY (2017)

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Systemic T Cells Immunosuppression of Glioma Stem Cell-Derived Exosomes Is Mediated by Monocytic Myeloid-Derived Suppressor Cells

Rossana Domenis et al.

PLOS ONE (2017)

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Cancer stem cell surface markers on normal stem cells

Won-Tae Kim et al.

BMB REPORTS (2017)

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Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15-CCR1 Chemokine Axis

Susumu Inamoto et al.

CLINICAL CANCER RESEARCH (2016)

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Tumor microenvironment for cancer stem cells

Kazuyoshi Kise et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

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Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling

Dongjun Peng et al.

CANCER RESEARCH (2016)

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Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease

Rona Yaeger et al.

GASTROENTEROLOGY (2016)

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Induction of protumoral CD11chigh macrophages by glioma cancer stem cells through GM-CSF

Yasuhiro Kokubu et al.

GENES TO CELLS (2016)

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Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells

Tze-Sian Chan et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

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Long non-coding RNA DILC regulates liver cancer stem cells via IL-6/STAT3 axis

Xue Wang et al.

JOURNAL OF HEPATOLOGY (2016)

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Cancer stem cells: understanding tumor hierarchy and heterogeneity

Jeremy N. Rich

MEDICINE (2016)

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ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

Ren-Hui Chen et al.

ONCOTARGET (2016)

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Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

Eunice Yuen Ting Lau et al.

CELL REPORTS (2016)

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Cancer-Associated Myeloid Regulatory Cells

Yannick De Vlaeminck et al.

FRONTIERS IN IMMUNOLOGY (2016)

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Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia

Saradhi Mallampati et al.

BLOOD (2015)

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Role of HLA-G and extracellular vesicles in renal cancer stem cell-induced inhibition of dendritic cell differentiation

Cristina Grange et al.

BMC CANCER (2015)

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Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche

Yoku Hayakawa et al.

CANCER CELL (2015)

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RORC1 Regulates Tumor-Promoting Emergency Granulo-Monocytopoiesis

Laura Strauss et al.

CANCER CELL (2015)

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Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer

Runbi Ji et al.

CELL CYCLE (2015)

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The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?

Vicki Plaks et al.

CELL STEM CELL (2015)

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Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms

Michele Cioffi et al.

CLINICAL CANCER RESEARCH (2015)

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Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity

Adriana Albini et al.

CONNECTIVE TISSUE RESEARCH (2015)

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Cancer Microenvironment: What Can We Learn from the Stem Cell Niche

Lukas Lacina et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

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Ovarian cancer stem-like cells elicit the polarization of M2 macrophages

Qing Zhang et al.

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Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

Wenchao Zhou et al.

NATURE CELL BIOLOGY (2015)

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Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

Alexandre Calon et al.

NATURE GENETICS (2015)

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Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis

Bin Shang et al.

SCIENTIFIC REPORTS (2015)

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Mir-152 inhibits cell proliferation and colony formation of CD133+ liver cancer stem cells by targeting KIT

Haili Huang et al.

TUMOR BIOLOGY (2015)

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MicroRNA-9 is associated with epithelial-mesenchymal transition, breast cancer stem cell phenotype, and tumor progression in breast cancer

Jae Moon Gwak et al.

BREAST CANCER RESEARCH AND TREATMENT (2014)

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Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

Brian Ruffell et al.

CANCER CELL (2014)

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Regulatory T cell subsets in human cancer: are they regulating for or against tumor progression?

Theresa L. Whiteside

CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)

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Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer

Roheena Z. Panni et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)

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Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma

Qing-Min Fan et al.

CANCER LETTERS (2014)

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Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells

Bin Wang et al.

CANCER RESEARCH (2014)

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MSC-Regulated MicroRNAs Converge on the Transcription Factor FOXP2 and Promote Breast Cancer Metastasis

Benjamin G. Cuiffo et al.

CELL STEM CELL (2014)

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Cancer Stem Cells in Prostate Cancer Chemoresistance

Jie Ni et al.

CURRENT CANCER DRUG TARGETS (2014)

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Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

Shanshan Wan et al.

GASTROENTEROLOGY (2014)

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Blockade of CD47-Mediated Cathepsin S/Protease-Activated Receptor 2 Signaling Provides a Therapeutic Target for Hepatocellular Carcinoma

Terence Kin-Wah Lee et al.

HEPATOLOGY (2014)

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Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell-Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4

Andrea Volonte et al.

JOURNAL OF IMMUNOLOGY (2014)

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A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

Haihui Lu et al.

NATURE CELL BIOLOGY (2014)

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Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling

Wan-Jiun Chen et al.

NATURE COMMUNICATIONS (2014)

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CD95 and CD95L promote and protect cancer stem cells

Paolo Ceppi et al.

NATURE COMMUNICATIONS (2014)

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Concise Review: Breast Cancer Stem Cells: Regulatory Networks, Stem Cell Niches, and Disease Relevance

Wenjun Guo

STEM CELLS TRANSLATIONAL MEDICINE (2014)

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Cancer stem cell immunology: key to understanding tumorigenesis and tumor immune escape?

Valentin S. Bruttel et al.

FRONTIERS IN IMMUNOLOGY (2014)

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The ID proteins: master regulators of cancer stem cells and tumour aggressiveness

Anna Lasorella et al.

NATURE REVIEWS CANCER (2014)

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Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming

Neha Tiwari et al.

CANCER CELL (2013)

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Gastric cancer stem cells: A novel therapeutic target

Shree Ram Singh

CANCER LETTERS (2013)

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Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Jonathan B. Mitchem et al.

CANCER RESEARCH (2013)

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Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

Lin Cheng et al.

CELL (2013)

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Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer

Kenneth J. Pienta et al.

INVESTIGATIONAL NEW DRUGS (2013)

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Mechanisms underlying helper T-cell plasticity: Implications for immune-mediated disease

Kiyoshi Hirahara et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

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Hepatic stem cell niches

Claus Kordes et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

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Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells

Lei Sun et al.

STEM CELLS (2013)

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The biological implication of cancer stem cells in hepatocellular carcinoma: a possible target for future therapy

Caecilia H. C. Sukowati et al.

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2013)

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Mechanisms of chemoresistance in cancer stem cells

Lissa Nurrul Abdullah et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2013)

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Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability

Liran I. Shlush et al.

BLOOD (2012)

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Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

Anne-Katrine Bonde et al.

BMC CANCER (2012)

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Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression

Zhao-Qiu Wu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

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Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

Arnout G. Schepers et al.

SCIENCE (2012)

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CD133+, CD166+CD44+, and CD24+CD44+Phenotypes Fail to Reliably Identify Cell Populations with Cancer Stem Cell Functional Features in Established Human Colorectal Cancer Cell Lines

Manuele Giuseppe Muraro et al.

STEM CELLS TRANSLATIONAL MEDICINE (2012)

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Coordinated regulation of myeloid cells by tumours

Dmitry I. Gabrilovich et al.

NATURE REVIEWS IMMUNOLOGY (2012)

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EZH2 Promotes Expansion of Breast Tumor Initiating Cells through Activation of RAF1-β-Catenin Signaling

Chun-Ju Chang et al.

CANCER CELL (2011)

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Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids

Jeanine M. L. Roodhart et al.

CANCER CELL (2011)

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Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

Cristina Grange et al.

CANCER RESEARCH (2011)

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Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

Theresa A. Proia et al.

CELL STEM CELL (2011)

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DNA-Damage Response in Tissue-Specific and Cancer Stem Cells

Cedric Blanpain et al.

CELL STEM CELL (2011)

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Myeloid cell population dynamics in healthy and tumor-bearing mice

Satoshi Ueha et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2011)

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Hepatocyte growth factor twenty years on: Much more than a growth factor

Takahiro Nakamura et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2011)

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Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

Masahisa Jinushi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Article Multidisciplinary Sciences

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

Christine L. Chaffer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Article Oncology

Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells

Tobias Schatton et al.

CANCER RESEARCH (2010)

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Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients

Tiziano Di Tomaso et al.

CLINICAL CANCER RESEARCH (2010)

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Plasticity of T-cell phenotype and function: the T helper type 17 example

Ariana Peck et al.

IMMUNOLOGY (2010)

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Glioma cancer stem cells induce immunosuppressive macrophages/microglia

Adam Wu et al.

NEURO-ONCOLOGY (2010)

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Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: N1 versus N2 TAN

Zvi G. Fridlender et al.

CANCER CELL (2009)

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Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

Francesco Colotta et al.

CARCINOGENESIS (2009)

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An Akt/Hypoxia-Inducible Factor-1α/Platelet-Derived Growth Factor-BB Autocrine Loop Mediates Hypoxia-Induced Chemoresistance in Liver Cancer Cells and Tumorigenic Hepatic Progenitor Cells

Chi Keung Lau et al.

CLINICAL CANCER RESEARCH (2009)

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Genomic advances and their impact on clinical trial design

Sumithra J. Mandrekar et al.

GENOME MEDICINE (2009)

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Altered macrophage differentiation and immune dysfunction in tumor development

Antonio Sica et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao et al.

NATURE (2006)

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Characterization of the expression of MHC proteins in human embryonic stem cells

M Drukker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

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Review Biochemistry & Molecular Biology

The hallmarks of cancer

D Hanahan et al.

CELL (2000)

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