4.8 Article

Flexible brain-computer interfaces

Journal

NATURE ELECTRONICS
Volume 6, Issue 2, Pages 109-118

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41928-022-00913-9

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Flexible electronics have potential applications in the development of brain-computer interfaces, addressing the limitations of traditional rigid electronics. They offer unique advantages in terms of flexibility, stretchability, and softness, impacting neuroscience, neuroprosthetic control, bioelectronic medicine, and brain and machine intelligence integration. Challenges regarding materials, device fabrication, and system integration need to be addressed to develop flexible brain-computer interfaces with broad applicability.
Brain-computer interfaces-which allow direct communication between the brain and external computers-have potential applications in neuroscience, medicine and virtual reality. Current approaches are, however, based on conventional rigid electronics and are limited by their intrinsic mechanical and geometrical mismatch with brain tissue. Flexible electronics, which can have mechanical properties compatible with the brain, could address these limitations and be used to create the next generation of brain-computer interfaces. Here we explore the use of flexible electronics in the development of brain-computer interfaces. We examine the unique advantages of flexible, stretchable and soft electronics in such interfaces and consider the potential impact of the technology on neuroscience, neuroprosthetic control, bioelectronic medicine, and brain and machine intelligence integration. We also explore the challenges in materials, device fabrication and system integration that need to be addressed to develop flexible brain-computer interfaces of general applicability. This Perspective explores the use of flexible electronics in the development of brain-computer interfaces, considering their potential impact on neuroscience, neuroprosthetic control, bioelectronic medicine, and brain and machine intelligence integration.

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