Journal
DIAGNOSTICS
Volume 12, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/diagnostics12112814
Keywords
autoimmune disease; IgG4-associated; IgG4-related disease; cardiac-gated imaging techniques; coronary artery disease; systemic vasculitis
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Coronary IgG4-RD, a rare fibro-inflammatory disorder, can present as tumor-like lesions. Early diagnosis is essential due to the vague clinical symptoms.
Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibro-inflammatory disorder. Coronary IgG4-RD has been scarcely reported and may present as tumor-like lesions. These pseudo-masses may be underdiagnosed mainly due to a vague clinical picture that can vary from complete lack of symptoms to acute coronary syndrome or sudden cardiac death. Early recognition of coronary IgG4-RD is essential to monitor disease activity and prevent life-threatening complications. We report a comprehensive non-invasive imaging evaluation of a patient affected by coronary IgG4-RD, which was diagnosed as an incidental finding during routine pre-laparoscopic cholecystectomy checkup. Non-invasive imaging revealed the presence of a peri-coronary soft-tissue mass that was stable at 12 months follow-up.
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