4.7 Article

Antileishmanial Activity of Clinanthus milagroanthus S. Leiva & Meerow (Amaryllidaceae) Collected in Peru

Related references

Note: Only part of the references are listed.
Article Plant Sciences

Alkaloid Composition and Biological Activities of the Amaryllidaceae Species Ismene amancaes (Ker Gawl.) Herb.

Marilu Roxana Soto-Vasquez et al.

Summary: This study identified the alkaloid composition and bioactive potential of an extract from the endemic Peruvian plant species Ismene amancaes. The extract contained lycoramine and exhibited inhibitory activity against enzymes and the Plasmodium falciparum strain FCR-3.

PLANTS-BASEL (2022)

Article Plant Sciences

Alkaloid profile in Pyrolirion albicans Herb. (Amaryllidaceae), a Peruvian endemic species

Hibert Huaylla et al.

Summary: The Amaryllidaceae family is widely distributed globally, with species of the subfamily Amaryllidoideae known for producing the alkaloid galanthamine used in Alzheimer's disease treatment. In Peru, a diverse range of Amaryllidoideae plants have been reported, some of which contain important bioactive alkaloids like galanthamine and montanine.

SOUTH AFRICAN JOURNAL OF BOTANY (2021)

Review Parasitology

Prevalence and associated factors of asymptomatic leishmaniasis: a systematic review and meta-analysis

Shahnewaj Bin Mannan et al.

Summary: Asymptomatic leishmaniasis is believed to be crucial in maintaining the transmission of Leishmania spp., and efforts to eliminate leishmaniasis depend on effectively managing asymptomatic cases. A meta-analysis of 111 original articles showed a high prevalence of asymptomatic leishmaniasis in endemic areas, with males being more susceptible to developing symptoms. Despite a lack of significant change over the past 40 years, asymptomatic cases remain a significant concern in the global fight against leishmaniasis.

PARASITOLOGY INTERNATIONAL (2021)

Article Parasitology

Antileishmanial activity evaluation of a natural amide and its synthetic analogs against Leishmania (V.) braziliensis: an integrated approach in vitro and in silico

Minelly A. da Silva et al.

Summary: Leishmaniasis is considered a neglected disease, leading to a lack of financial motivation for research efforts in finding biologically active substances. This study identified compounds with promising leishmanicidal activity, such as piplartine, and investigated their possible mechanisms of action.

PARASITOLOGY RESEARCH (2021)

Article Dermatology

Identification of Leishmania species by high-resolution DNA dissociation in cases of American cutaneous leishmaniasis

John Verrinder Veasey et al.

ANAIS BRASILEIROS DE DERMATOLOGIA (2020)

Review Plant Sciences

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

David J. Newman et al.

JOURNAL OF NATURAL PRODUCTS (2020)

Editorial Material Chemistry, Medicinal

Challenges and Opportunities for Drug Discovery in Developing Countries: The Example of Cutaneous Leishmaniasis

Abdrrahman S. Surur et al.

ACS MEDICINAL CHEMISTRY LETTERS (2020)

Article Infectious Diseases

In vitro activity and mode of action of phenolic compounds on Leishmania donovani

Christine Achiaa Antwi et al.

PLOS NEGLECTED TROPICAL DISEASES (2019)

Review Chemistry, Medicinal

Antiprotozoal alkaloid principles of the plant family Amaryllidaceae

Jerald J. Nair et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)

Article Biochemistry & Molecular Biology

N-oxide alkaloids from Crinum amabile (Amaryllidaceae)

Luciana R. Tallini et al.

MOLECULES (2018)

Review Medicine, Research & Experimental

Lycorine: A prospective natural lead for anticancer drug discovery

Mridul Roy et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Biochemistry & Molecular Biology

Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives

Francesco Saccoliti et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Alkaloid Constituents of the Amaryllidaceae Plant Amaryllis belladonna L.

Luciana R. Tallini et al.

MOLECULES (2017)

Review Chemistry, Medicinal

Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs

Gianni Colotti et al.

FUTURE MEDICINAL CHEMISTRY (2013)

Article Infectious Diseases

In Vitro and In Vivo Efficacy of Ether Lipid Edelfosine against Leishmania spp. and SbV-Resistant Parasites

Ruben E. Varela-M et al.

PLOS NEGLECTED TROPICAL DISEASES (2012)

Article Plant Sciences

Antiprotozoal alkaloids from Galanthus trojanus

Gulen Irem Kaya et al.

PHYTOCHEMISTRY LETTERS (2011)

Article Biochemistry & Molecular Biology

Homology modeling and docking study of xanthine oxidase of Arthrobacter sp XL26

R. G. Bodade et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2010)

Article Plant Sciences

In vitro antiprotozoal activity of alkaloids from Phaedranassa dubia (Amaryllidaceae)

Edison J. Osorio et al.

PHYTOCHEMISTRY LETTERS (2010)

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Molecular Basis of Antimony Treatment in Leishmaniasis

Paola Baiocco et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Microbiology

Activities of naphthylisoquinoline alkaloids and synthetic analogs against Leishmania major

Alicia Ponte-Sucre et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)

Article Microbiology

Aziridine-2,3-dicarboxylates, peptidomimetic cysteine protease inhibitors with antileishmanial activity

Alicia Ponte-Sucre et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

Article Plant Sciences

Crinane and lycorane type alkaloids from Zephyranthes citrina

MR Herrera et al.

PLANTA MEDICA (2001)

Article Biochemistry & Molecular Biology

South African Amaryllidaceae part VIII -: Alkaloids from Crinum macowanii

JJ Nair et al.

PHYTOCHEMISTRY (2000)