Balance Rehabilitation through Robot-Assisted Gait Training in Post-Stroke Patients: A Systematic Review and Meta-Analysis

Article Engineering, Biomedical

Effects of Balance Exercise Assist Robot training for patients with hemiparetic stroke: a randomized controlled trial

Seigo Inoue et al.

Summary: The study found that adding balance exercises using the BEAR to conventional inpatient rehabilitation can improve balance in patients with subacute stroke.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2022)

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Article Rehabilitation

The minimal clinically important difference in Berg Balance Scale scores among patients with early subacute stroke: a multicenter, retrospective, observational study

Shuntaro Tamura et al.

Summary: This retrospective clinical analysis estimated the MCID for early subacute stroke patients who require walking assistance and those who do not, using BBS scores and FAC changes as anchors. The study found that a 5-point improvement in BBS scores is a useful indicator for reducing the amount of assistance in patients who require walking assistance.

TOPICS IN STROKE REHABILITATION (2022)

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Review Neurosciences

Efficacy of Overground Robotic Gait Training on Balance in Stroke Survivors: A Systematic Review and Meta-Analysis

Matteo Lorusso et al.

Summary: Stroke often leads to motor control deficits, which in turn affect balance function and severely limit the activities of daily living for stroke survivors. This systematic review and meta-analysis aimed to explore the efficacy of overground robot-assisted gait training (o-RAGT) in balance recovery for individuals with stroke and investigate its effects on activities of daily living. The results suggest that o-RAGT does not provide better balance and activities of daily living outcomes compared to conventional therapy. Further well-designed randomized controlled trials are needed to investigate the efficacy of o-RAGT in balance for individuals with stroke.

BRAIN SCIENCES (2022)

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Article Rehabilitation

Effect of combined home-based, overground robotic-assisted gait training and usual physiotherapy on clinical functional outcomes in people with chronic stroke: A randomized controlled trial

Amy Wright et al.

Summary: A home-based over-ground robotic-assisted gait training program using the AlterG Bionic Leg orthosis was found to significantly improve clinical functional outcomes and physical activity levels in chronic stroke patients, with these improvements being maintained 22 weeks post-intervention.

CLINICAL REHABILITATION (2021)

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Review Neurosciences

Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies

Surojit Paul et al.

Summary: Stroke is a major cause of disability and death globally, with an increasing incidence particularly in younger age groups and low to middle-income countries. While treatment options are limited, advancements in recanalization therapy have shown promise in helping patients recover from ischemic stroke. Development of neuroprotective agents for acute ischemic stroke is urgently needed to protect the brain, extend the therapeutic time window, and improve outcomes.

EXPERIMENTAL NEUROLOGY (2021)

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Article Clinical Neurology

Early post-stroke rehabilitation for upper limb motor function using virtual reality and exoskeleton: equally efficient in older patients

Tereza Gueye et al.

Summary: The study evaluated the effectiveness of virtual reality therapy using Armeo in early post-stroke rehabilitation, specifically focusing on the elderly. Results showed that adding virtual reality therapy to daily rehabilitation programs was more effective in improving upper extremity motor performance compared to conventional physiotherapy, and this effectiveness did not diminish with patient age, suggesting it could be a promising addition to traditional physiotherapy in both older and younger stroke patients.

NEUROLOGIA I NEUROCHIRURGIA POLSKA (2021)

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Article Rehabilitation

The effects of lower extremity cross-training on gait and balance in stroke patients: a double-blinded randomized controlled trial

Chanhyun Park et al.

Summary: The study found that cross-training can significantly improve gait and balance in stroke patients, regardless of whether it is applied to the affected or unaffected side. This suggests that indirect interventions can help improve patients' motor function.

EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE (2021)

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Article Medicine, General & Internal

Effects of robot (SUBAR)-assisted gait training in patients with chronic stroke Randomized controlled trial

Cheon Ji Kang et al.

Summary: The study investigated the effects of SUBAR-assisted gait training in chronic stroke patients. Results showed improvements in some gait parameters, but no significant differences compared to conventional physiotherapy.

MEDICINE (2021)

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Review Nursing

Virtual reality for limb motor function, balance, gait, cognition and daily function of stroke patients: A systematic review and meta-analysis

Bohan Zhang et al.

Summary: This study found that VR interventions can effectively improve upper- and lower-limb motor function, balance, gait, and daily function of stroke patients, but do not provide benefits for cognition. The duration of VR intervention was also found to impact certain health benefits. Further research through large-scale multicentre randomized controlled trials is needed to investigate the impact of VR on cognitive function.

JOURNAL OF ADVANCED NURSING (2021)

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Review Engineering, Biomedical

Systematic review on wearable lower-limb exoskeletons for gait training in neuromuscular impairments

Antonio Rodriguez-Fernandez et al.

Summary: Wearable lower-limb exoskeletons show potential for improving walking ability, promoting exercise, and enhancing daily living activities for individuals with neuromuscular impairments. However, current limitations such as bulky devices and limited evidence of benefits in short-term trials highlight the need for further research and clinical trials to demonstrate their efficacy.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2021)

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Article Engineering, Biomedical

Effect of assist-as-needed robotic gait training on the gait pattern post stroke: a randomized controlled trial

J. F. Alingh et al.

Summary: The study compared the effects of AAN(mDOF) robotic and conventional training on the gait pattern and functional gait tasks of post-stroke rehabilitation patients. The findings suggest that AAN(mDOF) robotic training is not superior to conventional training in improving gait pattern, but may be more effective in addressing specific post-stroke gait abnormalities.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2021)

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Article Engineering, Biomedical

Effects of wearable ankle robotics for stair and over-ground training on sub-acute stroke: a randomized controlled trial

Ling-Fung Yeung et al.

Summary: This study found that robot-assisted stair training can be more effective in improving gait recovery and promoting independence than conventional training. Patients using SCAR robot showed significant improvement in gait recovery, while patients using PAAR robot demonstrated greater increase in walking speed.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2021)

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Article Geriatrics & Gerontology

Effectiveness of Nintendo Wii and Physical Therapy in Functionality, Balance, and Daily Activities in Chronic Stroke Patients

Elena Marques-Sule et al.

Summary: The study showed promising results in functionality, balance, and activities of daily living when adding virtual reality with Nintendo Wii to conventional physical therapy in chronic stroke survivors.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2021)

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Article Clinical Neurology

Changes in muscle architecture on ultrasound in patients early after stroke

Jong Moon Kim et al.

Summary: This study investigated differences in ultrasound-derived muscle architecture parameters of the hemiplegic limbs in patients with subacute stroke, finding reduced muscle thickness and increased echo intensity compared to the normal side. There were no significant correlations between ultrasound findings and Motricity Index.

NEUROREHABILITATION (2021)

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Article Health Care Sciences & Services

Effects of a Brain-Computer Interface-Operated Lower Limb Rehabilitation Robot on Motor Function Recovery in Patients with Stroke

Chao Li et al.

Summary: The study aimed to investigate the impact of BCI-LLRR on functional recovery from stroke and explore the mechanisms. Results showed significant improvement in leg function and NIHSS scores in the treatment group compared to controls after 4 weeks, with further improvement at 3 months. The MEP amplitude and latency of the treatment group also significantly improved, while the effect on fractional anisotropy values was not significant.

JOURNAL OF HEALTHCARE ENGINEERING (2021)

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Article Engineering, Biomedical

Effects of an exoskeleton-assisted gait training on post-stroke lower-limb muscle coordination

Fangshi Zhu et al.

Summary: This study found that using a powered exoskeleton for gait training can alter neuromuscular coordination in stroke patients, especially on the paretic side. However, after training, the complexity, module composition, and activation timing of neuromuscular coordination remained unchanged.

JOURNAL OF NEURAL ENGINEERING (2021)

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Article Engineering, Biomedical

Evidence of neuroplasticity with robotic hand exoskeleton for post-stroke rehabilitation: a randomized controlled trial

Neha Singh et al.

Summary: The study demonstrates that robotic-exoskeleton training improves motor outcomes and cortical excitability in patients with stroke. Neurophysiological changes in the robotic group are likely a result of plastic reorganization and use-dependent plasticity.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2021)

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Review Environmental Sciences

Economic Burden of Stroke Disease: A Systematic Review

Thinni Nurul Rochmah et al.

Summary: The study analyzed the burden of stroke using a systematic review method. It found that the high economic burden of stroke is mainly due to hospitalization costs.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Biotechnology & Applied Microbiology

Robot-Assisted Gait Training Plan for Patients in Poststroke Recovery Period: A Single Blind Randomized Controlled Trial

Deng Yu et al.

Summary: This study investigated the effects of a short-term robot-assisted gait training plan for patients with stroke and found significant improvements in space parameters for the robot-assisted training group, while the conventional training group showed improvements in time parameters. Both groups showed progress in Fugl-Meyer Assessment and Timed Up and Go test scores, but there were no significant differences between the groups.

BIOMED RESEARCH INTERNATIONAL (2021)

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Article Rehabilitation

EFFECTIVENESS OF ROBOTIC BALANCE TRAINING ON POSTURAL INSTABILITY IN PATIENTS WITH MILD PARKINSON'S DISEASE: A PILOT, SINGLE-BLIND, RANDOMIZED CONTROLLED TRIAL

Stefania Spina et al.

Summary: The study found that robot-assisted balance training can be more effective in improving postural stability in patients with mild Parkinson's disease compared to conventional balance treatment. The experimental group showed better results in primary outcome measures, while no significant differences between groups were found in secondary outcomes.

JOURNAL OF REHABILITATION MEDICINE (2021)

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Review Rehabilitation

Energy consumption and cost during walking with different modalities of assistance after stroke: a systematic review and meta-analysis

Nina Lefeber et al.

DISABILITY AND REHABILITATION (2020)

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Article Multidisciplinary Sciences

A randomized controlled study incorporating an electromechanical gait machine, the Hybrid Assistive Limb, in gait training of patients with severe limitations in walking in the subacute phase after stroke

Anneli Wall et al.

PLOS ONE (2020)

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Review Geriatrics & Gerontology

Muscle mass, strength, and physical performance predicting activities of daily living: a meta-analysis

Daniel X. M. Wang et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2020)

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Article Rehabilitation

Task-based mirror therapy enhances the upper limb motor function in subacute stroke patients: a randomized control trial

Hamza Y. Madhoun et al.

EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE (2020)

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Article Engineering, Biomedical

Biomedical Serious Game System for Lower Limb Motor Rehabilitation of Hemiparetic Stroke Patients

F. Noveletto et al.

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (2020)

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Article Clinical Neurology

Dynamic Stability and Trunk Control Improvements Following Robotic Balance and Core Stability Training in Chronic Stroke Survivors: A Pilot Study

Alice De Luca et al.

FRONTIERS IN NEUROLOGY (2020)

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Article Neurosciences

Effects of gait exercise assist robot (GEAR) on subjects with chronic stroke: A randomized controlled pilot trial

Tomoyuki Ogino et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2020)

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Article Rehabilitation

Effects of trunk stabilization training robot on postural control and gait in patients with chronic stroke: a randomized controlled trial

Ji Hong Min et al.

INTERNATIONAL JOURNAL OF REHABILITATION RESEARCH (2020)

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Article Multidisciplinary Sciences

Neuroplastic effects of end-effector robotic gait training for hemiparetic stroke: a randomised controlled trial

Hayeon Kim et al.

SCIENTIFIC REPORTS (2020)

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Review Orthopedics

Bobath therapy is inferior to task-specific training and not superior to other interventions in improving lower limb activities after stroke: a systematic review

Katharine Scrivener et al.

JOURNAL OF PHYSIOTHERAPY (2020)

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Article Clinical Neurology

Effectiveness of physiotherapy interventions in brain plasticity, balance and functional ability in stroke survivors: A randomized controlled trial

Umi Budi Rahayu et al.

NEUROREHABILITATION (2020)

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Review Nursing

Robot-assisted therapy for balance function rehabilitation after stroke: A systematic review and meta-analysis

Qing-Xiang Zheng et al.

INTERNATIONAL JOURNAL OF NURSING STUDIES (2019)

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Article Rehabilitation

Effectiveness of upper-limb robotic-assisted therapy in the early rehabilitation phase after stroke: A single-blind, randomised, controlled trial

Stephanie Dehem et al.

ANNALS OF PHYSICAL AND REHABILITATION MEDICINE (2019)

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Article Engineering, Biomedical

Robot-assisted gait training for balance and lower extremity function in patients with infratentorial stroke: a single-blinded randomized controlled trial

Ha Yeon Kim et al.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2019)

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Article Clinical Neurology

Efficacy of end-effector Robot-Assisted Gait Training in subacute stroke patients: Clinical and gait outcomes from a pilot bi-centre study

Irene Aprile et al.

NEUROREHABILITATION (2019)

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Article Neurosciences

Robot-Assisted Stair Climbing Training on Postural Control and Sensory Integration Processes in Chronic Post-stroke Patients: A Randomized Controlled Clinical Trial

Marialuisa Gandolfi et al.

FRONTIERS IN NEUROSCIENCE (2019)

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Article Rehabilitation

Effects of robot-(Morning Walk®) assisted gait training for patients after stroke: a randomized controlled trial

JaYoung Kim et al.

CLINICAL REHABILITATION (2019)

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Review Rehabilitation

Effectiveness of Neuromuscular Electrical Stimulation on Lower Limbs of Patients With Hemiplegia After Chronic Stroke: A Systematic Review

Zhongqiu Hong et al.

ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2018)

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Article Rehabilitation

Virtual Reality for Upper Limb Rehabilitation in Subacute and Chronic Stroke: A Randomized Controlled Trial

Pawel Kiper et al.

ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2018)

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Article Computer Science, Interdisciplinary Applications

Feasibility of a smartphone-based balance assessment system for subjects with chronic stroke

You-Ruei Hou et al.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2018)

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Review Neurosciences

Mirror therapy for improving lower limb motor function and mobility after stroke: A systematic review and meta-analysis

P. Broderick et al.

GAIT & POSTURE (2018)

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Review Clinical Neurology

Global Burden of Stroke

Mira Katan et al.

SEMINARS IN NEUROLOGY (2018)

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Article Clinical Neurology

The effects of robot-assisted gait training using virtual reality and auditory stimulation on balance and gait abilities in persons with stroke

Jaeho Park et al.

NEUROREHABILITATION (2018)

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Article Multidisciplinary Sciences

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

Yoon-Hee Choi et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2018)

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Article Rehabilitation

Robot-assisted gait training effectively improved lateropulsion in subacute stroke patients: a single-blinded randomized controlled trial

Nari Yun et al.

EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE (2018)

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Article Rehabilitation

The effects of body weight-supported treadmill training on static and dynamic balance in stroke patients: A pilot, single-blind, randomized trial

Rustem Mustafaoglu et al.

TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION (2018)

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Article Clinical Neurology

High-Intensity Interval Training After Stroke: An Opportunity to Promote Functional Recovery, Cardiovascular Health, and Neuroplasticity

Jennifer Crozier et al.

NEUROREHABILITATION AND NEURAL REPAIR (2018)

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Review Rehabilitation

Adding electrical stimulation during standard rehabilitation after stroke to improve motor function. A systematic review and meta-analysis

Sharareh Sharififar et al.

ANNALS OF PHYSICAL AND REHABILITATION MEDICINE (2018)

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Article Neurosciences

Transcutaneous Vagus Nerve Stimulation Combined with Robotic Rehabilitation Improves Upper Limb Function after Stroke

Fioravante Capone et al.

NEURAL PLASTICITY (2017)

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Review Clinical Neurology

Robotics in Lower-Limb Rehabilitation after Stroke

Xue Zhang et al.

BEHAVIOURAL NEUROLOGY (2017)

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Article Clinical Neurology

Effects of robot-assisted gait training on spatiotemporal gait parameters and balance in patients with chronic stroke: A randomized controlled pilot trial

Dae-Hyouk Bang et al.

NEUROREHABILITATION (2016)

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Review Biotechnology & Applied Microbiology

Effect of Virtual Reality on Postural and Balance Control in Patients with Stroke: A Systematic Literature Review

Ling Chen et al.

BIOMED RESEARCH INTERNATIONAL (2016)

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Article Engineering, Biomedical

Effects of Innovative WALKBOT Robotic-Assisted Locomotor Training on Balance and Gait Recovery in Hemiparetic Stroke: A Prospective, Randomized, Experimenter Blinded Case Control Study With a Four-Week Follow-Up

Soo-Yeon Kim et al.

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (2015)

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Article Rehabilitation

Feasibility and efficacy of high-speed gait training with a voluntary driven exoskeleton robot for gait and balance dysfunction in patients with chronic stroke: nonrandomized pilot study with concurrent control

Takahiko Yoshimoto et al.

INTERNATIONAL JOURNAL OF REHABILITATION RESEARCH (2015)

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Review Peripheral Vascular Disease

Secondary stroke prevention: challenges and solutions

Charles Esenwa et al.

VASCULAR HEALTH AND RISK MANAGEMENT (2015)

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Review Multidisciplinary Sciences

What Is the Evidence for Physical Therapy Poststroke? A Systematic Review and Meta-Analysis

Janne Marieke Veerbeek et al.

PLOS ONE (2014)

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Article Peripheral Vascular Disease

New Evidence for Therapies in Stroke Rehabilitation

Bruce H. Dobkin et al.

CURRENT ATHEROSCLEROSIS REPORTS (2013)

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Review Orthopedics

The Berg Balance Scale has high intra- and inter-rater reliability but absolute reliability varies across the scale: a systematic review

Stephen Downs et al.

JOURNAL OF PHYSIOTHERAPY (2013)

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Article Geriatrics & Gerontology

A best practice fall prevention exercise program to improve balance, strength/power, and psychosocial health in older adults: study protocol for a randomized controlled trial

Yves J. Gschwind et al.

BMC GERIATRICS (2013)

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Review Clinical Neurology

Robot-assisted Therapy in Stroke Rehabilitation

Won Hyuk Chang et al.

JOURNAL OF STROKE (2013)

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Article Engineering, Biomedical

Pilot study of Lokomat versus manual-assisted treadmill training for locomotor recovery post-stroke

Kelly P. Westlake et al.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2009)

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Article Clinical Neurology

Multicenter Randomized Clinical Trial Evaluating the Effectiveness of the Lokomat in Subacute Stroke

Joseph Hidler et al.

NEUROREHABILITATION AND NEURAL REPAIR (2009)

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Balance Rehabilitation through Robot-Assisted Gait Training in Post-Stroke Patients: A Systematic Review and Meta-Analysis

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