Journal
BRAIN SCIENCES
Volume 12, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/brainsci12111531
Keywords
coronavirus; COVID-19; SARS-CoV-2; neurological impairment; viral encephalitis; coma
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The COVID-19 virus often leads to neurological complications such as headaches, seizures, coma, and encephalitis. Recent studies have shed light on the pathophysiology of viral involvement in nervous-system impairment. This research evaluated the relationship between COVID-19 infection and the central nervous system.
The COVID-19 virus frequently causes neurological complications. These have been described in various forms in adults and children. Headache, seizures, coma, and encephalitis are some of the manifestations of SARS-CoV-2-induced neurological impairment. Recent publications have revealed important aspects of viral pathophysiology and its involvement in nervous-system impairment in humans. We evaluated the latest literature describing the relationship between COVID-19 infection and the central nervous system. We searched three databases for observational and interventional studies in adults published between December 2019 and September 2022. We discussed in narrative form the neurological impairment associated with COVID-19, including clinical signs and symptoms, imaging abnormalities, and the pathophysiology of SARS-CoV2-induced neurological damage.
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