☆ 4.6 Article

Antibiotic-Loaded Coatings to Reduce Fracture-Related Infections: Retrospective Case Series of Patients with Increased Infectious Risk

ANTIBIOTICS-BASEL (2023)

Related references

Note: Only part of the references are listed.

Article Orthopedics

A major trauma centre experience with gentamicin-coated tibial intramedullary nails (ETN PROtect™) in acute primary open fracture fixation and complex revision surgery

Kavi H. Patel et al.

Summary: The use of ETN PROtect(R) nail in high-risk patients and those with aseptic non-unions shows promising outcomes in preventing implant-related infection. However, caution should be exercised in using them for previously established FRI/osteomyelitis cases, as no benefit over uncoated nails was observed in our limited study.

EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY (2023)

Add to Collection

Article Infectious Diseases

What Is the Most Effective Empirical Antibiotic Treatment for Early, Delayed, and Late Fracture-Related Infections?

Susanne Baertl et al.

Summary: This study aimed to investigate antibiotic susceptibility profiles for fracture-related infections (FRI) and identified the most effective empiric antibiotic treatments for early, delayed, and late-onset FRI. The results showed that meropenem + vancomycin, gentamicin + vancomycin, and co-amoxiclav + glycopeptide were the best therapeutic options for FRI, regardless of the onset of infection.

ANTIBIOTICS-BASEL (2022)

Add to Collection

Article Infectious Diseases

Causative Pathogens Do Not Differ between Early, Delayed or Late Fracture-Related Infections

Ruth A. Corrigan et al.

Summary: This study investigated pathogens isolated from fracture-related infections (FRIs) over different time periods and found that early or delayed infections are likely to be polymicrobial, while late infections are more likely to be culture-negative or monomicrobial. Staphylococcus aureus was the most commonly isolated pathogen, but there was no evidence of differences in pathogens isolated at different stages of infection.

ANTIBIOTICS-BASEL (2022)

Add to Collection

Article Critical Care Medicine

The influence of biomechanical stability on bone healing and fracture-related infection: the legacy of Stephan Perren

Andrew L. Foster et al.

Summary: Bone healing is a complex process influenced by various biological and biomechanical factors. Construct stability is crucial for preventing and treating fracture-related infections. Stephan Perren's theories have had a profound impact on surgical techniques and implant development for the past 50 years.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2021)

Add to Collection

Article Critical Care Medicine

Reconstruction of infected post-traumatic bone defects of the distal femur with the Compress® implant. Preliminary results of a staged non-biological strategy

Pablo S. Corona et al.

Summary: This study retrospectively reviewed 10 patients who underwent non-biological reconstruction with Compress (R) implants for massive infected defects of the distal femur with joint involvement. Limb salvage was achieved in all cases, with high survivorship and functional outcomes. However, aseptic loosening occurred in two patients, highlighting the importance of careful monitoring in the early postoperative period.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

Uncoated vs. Antibiotic-Coated Tibia Nail in Open Diaphyseal Tibial Fracture (42 according to AO Classification): A Single Center Experience

Tommaso Greco et al.

Summary: Antibiotic-coated nails are crucial in the treatment of open tibia fractures, improving fracture healing rate and reducing infection rate. This study found no deep wound infections when using antibiotic-coated nails, and good fracture healing outcomes.

BIOMED RESEARCH INTERNATIONAL (2021)

Add to Collection

Article Critical Care Medicine

Use of antibiotic coated intramedullary nails in open tibia fractures: A European medical resource use and cost-effectiveness analysis

D. Franz et al.

Summary: The study found that using gentamicin-coated intramedullary tibial nails in high risk patients with open tibial fractures can significantly reduce infection rates and lead to cost savings.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2021)

Add to Collection

Review Materials Science, Multidisciplinary

Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review

Gang Tan et al.

Summary: Orthopedic implant failure is a common complication of orthopedic surgery, often caused by peri-implant infection and aseptic loosening. There are various methods to treat these complications, such as revision surgery, but preventing peri-implant infection could bring significant social benefits.

COATINGS (2021)

Add to Collection

Article Multidisciplinary Sciences

The epidemiology of fracture-related infections in Germany

Nike Walter et al.

Summary: The prevalence of FRI in Germany increased from 2008 to 2018, especially in older patients, with about 1% of fracture patients developing FRI. Patients aged 60-79 accounted for a large proportion, with increasing prevalence with age.

SCIENTIFIC REPORTS (2021)

Add to Collection

Article Orthopedics

Treatment of severely open tibial fractures, non-unions, and fracture-related infections with a gentamicin-coated tibial nail-clinical outcomes including quality of life analysis and psychological ICD-10-based symptom rating

Nike Walter et al.

Summary: The use of a gentamicin-coated intramedullary nail can effectively promote bone consolidation, reduce the occurrence of infections, and improve quality of life in patients with high infection risks. However, significantly reduced quality of life after treatment highlights the need for further efforts to enhance surgical treatment strategies and psychological support.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2021)

Add to Collection

Article Polymer Science

Clinical Application of Antibacterial Hydrogel and Coating in Orthopaedic and Traumatology Surgery

Daniele De Meo et al.

Summary: Implant related infection is a common complication in orthopaedic and trauma surgery, with local antibiotic treatment strategies becoming increasingly important. While there are two available coatings on the market, their therapeutic use is less explored, though current evidence indicates their efficacy in prophylaxis against infections. This article aims to summarize recent evidence on the clinical application of antibacterial hydrogels and coatings, as well as suggest potential future applications.

GELS (2021)

Add to Collection

Article Microbiology

Antibiotic-Loaded Hydrogel Coating to Reduce Early Postsurgical Infections in Aseptic Hip Revision Surgery: A Retrospective, Matched Case-Control Study

Daniele De Meo et al.

MICROORGANISMS (2020)

Add to Collection

Review Chemistry, Physical

Bacterial adhesion on orthopedic implants

Urska Filipovic et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2020)

Add to Collection

Article Orthopedics

Definition and diagnosis of fracture-related infection

Martin McNally et al.

EFORT OPEN REVIEWS (2020)

Add to Collection

Review Biochemistry & Molecular Biology

Gentamicin-Coated Tibia Nail in Fractures and Nonunion to Reduce Fracture-Related Infections: A Systematic Review

Daniele De Meo et al.

MOLECULES (2020)

Add to Collection

Article Orthopedics

A Predictive Score for Determining Risk of Surgical Site Infection After Orthopaedic Trauma Surgery

Brent T. Wise et al.

JOURNAL OF ORTHOPAEDIC TRAUMA (2019)

Add to Collection

Article Orthopedics

Economic Evaluation of Antibacterial Coatings on Healthcare Costs in First Year Following Total Joint Arthroplasty

Maria Teresa Trentinaglia et al.

JOURNAL OF ARTHROPLASTY (2018)

Add to Collection

Article Orthopedics

Complications After Revision Total Hip Arthroplasty in the Medicare Population

Sameer Badarudeen et al.

JOURNAL OF ARTHROPLASTY (2017)

Add to Collection

Article Orthopedics

Fast-resorbable antibiotic-loaded hydrogel coating to reduce post-surgical infection after internal osteosynthesis: a multicenter randomized controlled trial

Kostantinos Malizos et al.

JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY (2017)

Add to Collection

Review Emergency Medicine

The role of biofilm on orthopaedic implants: the Holy Grail of post-traumatic infection management?

C. Mauffrey et al.

EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY (2016)

Add to Collection

Review Critical Care Medicine

The use of gentamicin-coated nails in complex open tibia fracture and revision cases: A retrospective analysis of a single centre case series and review of the literature

W. J. Metsemakers et al.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2015)

Add to Collection

Article Infectious Diseases

Evidence of MRSE on a gentamicin and vancomycin impregnated polymethyl-methacrylate (PMMA) bone cement spacer after two-stage exchange arthroplasty due to periprosthetic joint infection of the knee

Jan Schmolders et al.

BMC INFECTIOUS DISEASES (2014)

Add to Collection

Article Orthopedics

Does Implant Coating With Antibacterial-Loaded Hydrogel Reduce Bacterial Colonization and Biofilm Formation in Vitro?

Lorenzo Drago et al.

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2014)

Add to Collection

Article Orthopedics

Efficacy of antibacterial-loaded coating in an in vivo model of acutely highly contaminated implant

Gianluca Giavaresi et al.

INTERNATIONAL ORTHOPAEDICS (2014)

Add to Collection

Review Orthopedics

Systematic review and meta-analysis of the additional benefit of local prophylactic antibiotic therapy for infection rates in open tibia fractures treated with intramedullary nailing

Joyce Craig et al.

INTERNATIONAL ORTHOPAEDICS (2014)

Add to Collection

Article Critical Care Medicine

Predictors of poor outcomes following deep infection after internal fixation of ankle fractures

Mikko T. Ovaska et al.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2013)

Add to Collection

Article Critical Care Medicine

Prophylaxis and treatment of implant-related infections by antibiotic-coated implants: a review

Gerhard Schmidmaier et al.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2006)

Add to Collection

© Peeref 2019-2024. All rights reserved.