Related references
Note: Only part of the references are listed.Enhanced phosphate absorption in intestinal epithelial cell-specific NHE3 knockout mice
Jianxiang Xue et al.
ACTA PHYSIOLOGICA (2022)
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Yongxiang Zhao et al.
NATURE COMMUNICATIONS (2022)
The Na+/H+ Exchanger 3 in the Intestines and the Proximal Tubule of the Kidney: Localization, Physiological Function, and Key Roles in Angiotensin II-Induced Hypertension
Sarah M. Nwia et al.
FRONTIERS IN PHYSIOLOGY (2022)
DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension
Ashley Pitzer et al.
CIRCULATION RESEARCH (2022)
Dapagliflozin Prevents Kidney Glycogen Accumulation and Improves Renal Proximal Tubule Cell Functions in a Mouse Model of Glycogen Storage Disease Type 1b
Mariavittoria D'Acierno et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2022)
Further delineation of SLC9A3-related congenital sodium diarrhea
Ema Bogdanic et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2022)
Inherited Tubulopathies of the Kidney Insights from Genetics
Mallory L. Downie et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)
A case series of adult patients affected by EAST/SeSAME syndrome suggests more severe disease in subjects bearing KCNJ10 truncating mutations
Yoko Suzumoto et al.
INTRACTABLE & RARE DISEASES RESEARCH (2021)
Urinary proteomics reveals key markers of salt sensitivity in hypertensive patients during saline infusion
Vittoria Matafora et al.
JOURNAL OF NEPHROLOGY (2021)
Pure Gitelman-like syndrome secondary to SLC26A4 (pendrin) mutation
Francesco Trepiccione et al.
KIDNEY INTERNATIONAL (2021)
Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT-Agtr1a-/- Mice
Xiao Chun Li et al.
HYPERTENSION (2021)
Empagliflozin Inhibits Proximal Tubule NHE3 Activity, Preserves GFR, and Restores Euvolemia in Nondiabetic Rats with Induced Heart Failure
Avio A. Borges-Junior et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)
New Insights into the Critical Importance of Intratubular Na+/H+ Exchanger 3 and Its Potential Therapeutic Implications in Hypertension
Jia Long Zhuo et al.
CURRENT HYPERTENSION REPORTS (2021)
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
Bin Zhou et al.
LANCET (2021)
High Blood Pressure and Cardiovascular Disease
Flavio D. Fuchs et al.
HYPERTENSION (2020)
The global epidemiology of hypertension
Katherine T. Mills et al.
NATURE REVIEWS NEPHROLOGY (2020)
Modulation of brain cation-Cl- cotransport via the SPAK kinase inhibitor ZT-1a
Jinwei Zhang et al.
NATURE COMMUNICATIONS (2020)
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea
Jianxiang Xue et al.
CLINICAL SCIENCE (2020)
Looking beyond Entecavir to discover Gitelman Syndrome in a 50 year-old man
M. Simeoni et al.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2020)
Hypokalemia and severe renal loss of sodium - Pendred syndrome mimicking Gitelman syndrome
Sandrine Lemoine et al.
KIDNEY INTERNATIONAL (2020)
ENaC in Salt-Sensitive Hypertension: Kidney and Beyond
Ashley L. Pitzer et al.
CURRENT HYPERTENSION REPORTS (2020)
Distal convoluted tubule Cl- concentration is modulated via K+ channels an transporters
Xiao-Tong Su et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2020)
Role of Pendrin in the Pathophysiology of Aldosterone-Induced Hypertension
Shigeru Shibata
AMERICAN JOURNAL OF HYPERTENSION (2019)
Proximal Tubule-Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) in the Kidney Attenuates Ang II (Angiotensin II)-Induced Hypertension in Mice
Xiao C. Li et al.
HYPERTENSION (2019)
ERK1,2 Signalling Pathway along the Nephron and Its Role in Acid-base and Electrolytes Balance
Giovanna Capolongo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
THE SLC9A-C MAMMALIAN Na+/H+ EXCHANGER FAMILY: MOLECULES, MECHANISMS, AND PHYSIOLOGY
S. F. Pedersen et al.
PHYSIOLOGICAL REVIEWS (2019)
The Molecular Genetics of Gordon Syndrome
Holly Mabillard et al.
GENES (2019)
Superoxide increases surface NKCC2 in the rat thick ascending limbs via PKC
Mohammed Ziaul Haque et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2019)
Role of Pendrin in the Pathophysiology of Aldosterone-Induced Hypertension
Shigeru Shibata
AMERICAN JOURNAL OF HYPERTENSION (2019)
Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin
Daigoro Hirohama et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)
Salt-Losing Tubulopathies in Children: What's New, What's Controversial?
Robert Kleta et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)
Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors
Thomas R. Kleyman et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)
Type 2 Diabetes and Thiazide Diuretics
Andre J. Scheen
CURRENT DIABETES REPORTS (2018)
Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel
Ming-Xiao Wang et al.
KIDNEY INTERNATIONAL (2018)
Proximal Tubule-Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) Promotes the Pressure-Natriuresis Response and Lowers Blood Pressure in Mice
Xiao C. Li et al.
HYPERTENSION (2018)
Double Knockout of the Na+-Driven Cl-/HCO3--Exchanger and Na+/Cl- Cotransporter Induces Hypokalemia and Volume Depletion
Anne Sinning et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation
Hong Soon Kang et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
A Missense Mutation in the Extracellular Domain of αENaC Causes Liddle Syndrome
Mahdi Salih et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis
Robert A. Fenton et al.
KIDNEY INTERNATIONAL (2017)
Pendred syndrome
Jean-Louis Wemeau et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Calcineurin inhibitor cyclosporine A activates renal Na-K-Cl cotransporters via local and systemic mechanisms
K. I. Blankenstein et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases
Israel Hanukoglu et al.
GENE (2016)
Potassium Modulates Electrolyte Balance and Blood Pressure through Effects on Distal Cell Voltage and Chloride
Andrew S. Terker et al.
CELL METABOLISM (2015)
Relative Roles of Principal and Intercalated Cells in the Regulation of Sodium Balance and Blood Pressure
Regine Chambrey et al.
CURRENT HYPERTENSION REPORTS (2015)
Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea
Andreas R. Janecke et al.
HUMAN MOLECULAR GENETICS (2015)
Collecting Duct Principal Cell Transport Processes and Their Regulation
David Pearce et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)
Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines
Xiao C. Li et al.
PHYSIOLOGICAL REPORTS (2015)
Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3
Robert A. Fenton et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2015)
WNK4 is the major WNK positively regulating NCC in the mouse kidney
Daiei Takahashi et al.
BIOSCIENCE REPORTS (2014)
Electroneutral absorption of NaCl by the aldosterone-sensitive distal nephron: implication for normal electrolytes homeostasis and blood pressure regulation
Dominique Eladari et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Health effects of sodium and potassium in humans
Paul K. Whelton et al.
CURRENT OPINION IN LIPIDOLOGY (2014)
Physiology and pathophysiology of SLC12A1/2 transporters
Nicolas Markadieu et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
The WNK-SPAK/OSR1 pathway: Master regulator of cation-chloride cotransporters
Dario R. Alessi et al.
SCIENCE SIGNALING (2014)
Intestinal Inhibition of the Na+/H+ Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na+ Uptake in Humans
Andrew G. Spencer et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Physiology and pathophysiology of the renal Na-K-2Cl cotransporter (NKCC2)
Hayo Castrop et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2014)
Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy
Takayasu Mori et al.
BIOCHEMICAL JOURNAL (2013)
The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
Akihito Ohta et al.
BIOCHEMICAL JOURNAL (2013)
Mineralocorticoid Receptor Phosphorylation Regulates Ligand Binding and Renal Response to Volume Depletion and Hyperkalemia
Shigeru Shibata et al.
CELL METABOLISM (2013)
Overexpression of Pendrin in Intercalated Cells Produces Chloride-Sensitive Hypertension
Thibaut Jacques et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)
Renal intercalated cells are rather energized by a proton than a sodium pump
Regine Chambrey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Hyperphosphorylation of Na-K-2Cl Cotransporter in Thick Ascending Limbs of Dahl Salt-Sensitive Rats
Gustavo R. Ares et al.
HYPERTENSION (2012)
Antihypertensive and Laxative Effects by Pharmacological Inhibition of Sodium-Proton-Exchanger Subtype 3-Mediated Sodium Absorption in the Gut
Dominik Linz et al.
HYPERTENSION (2012)
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities
Lynn M. Boyden et al.
NATURE (2012)
Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure
Manoocher Soleimani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Molecular Mechanisms of Experimental Salt-Sensitive Hypertension
Bina Joe et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2012)
The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base Homeostasis
Carsten A. Wagner et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)
Neural Precursor Cell-expressed Developmentally Down-regulated Protein 4-2 (Nedd4-2) Regulation by 14-3-3 Protein Binding at Canonical Serum and Glucocorticoid Kinase 1 (SGK1) Phosphorylation Sites
Sindhu Chandran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways
Ciaran Richardson et al.
JOURNAL OF CELL SCIENCE (2011)
Phosphoproteomic analysis of AT1 receptor-mediated signaling responses in proximal tubules of angiotensin II-induced hypertensive rats
Xiao C. Li et al.
KIDNEY INTERNATIONAL (2011)
NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension
Monica Carmosino et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2011)
Molecular regulation of NKCC2 in the thick ascending limb
Gustavo R. Ares et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl-/HCO3- exchanger activity and impairs bicarbonate secretion in kidney collecting duct
Hassane Amlal et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice
Francoise Leviel et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
SPAK-Knockout Mice Manifest Gitelman Syndrome and Impaired Vasoconstriction
Sung-Sen Yang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells
Ruwan Gunaratne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule
Daniel Ackermann et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Posttranslational mechanisms associated with reduced NHE3 activity in adult vs. young prehypertensive SHR
Renato O. Crajoinas et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli
Anne D. M. Riquier-Brison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
The regulation of proximal tubular salt transport in hypertension: an update
Xiaoyan Wang et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2009)
Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure
Akihito Ohta et al.
HUMAN MOLECULAR GENETICS (2009)
Epilepsy, Ataxia, Sensorineural Deafness, Tubulopathy, and KCNJ10 Mutations.
Detlef Bockenhauer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10
Ute I. Scholl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
CGMP decreases surface NKCC2 levels in the thick ascending limb: role of phosphodiesterase 2 (PDE2)
Gustavo R. Ares et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension
Giovambattista Capasso et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Open probability of the epithelial sodium channel is regulated by intracellular sodium
Arun Anantharam et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage
KK Knight et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Familial hyperkalemic hypertension
Juliette Hadchouel et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Channels, carriers, and pumps in the pathogenesis of sodium-sensitive hypertension
G Capasso et al.
SEMINARS IN NEPHROLOGY (2005)
Altered expression of renal apical plasma membrane Na+ transporters in the early phase of genetic hypertension
G Capasso et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Novel mutations in epithelial sodium channel (ENaC) subunit genes and phenotypic expression of multisystem pseudohypoaldosteronism
O Edelheit et al.
CLINICAL ENDOCRINOLOGY (2005)
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters
G Gamba
PHYSIOLOGICAL REVIEWS (2005)
Adducin polymorphism - Detection and impact on hypertension and related disorders
G Bianchi et al.
HYPERTENSION (2005)
Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine
WT Noonan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
Liddle's syndrome caused by a novel mutation in the proline-rich PY motif of the epithelial sodium channel beta-subunit
M Furuhashi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Urinary potassium excretion and sodium sensitivity in blacks
A Aviv et al.
HYPERTENSION (2004)
Mechanism of iodide/chloride exchange by pendrin
A Yoshida et al.
ENDOCRINOLOGY (2004)
Altered renal distal tubule structure and renal Na+ and Ca2+ handling in a mouse model for Gitelman's syndrome
J Loffing et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)
NaCl restriction upregulates renal Slc26a4 through subcellular redistribution -: Role in Cl- conservation
SM Wall et al.
HYPERTENSION (2004)
Plasma sodium and hypertension
HE de Wardener et al.
KIDNEY INTERNATIONAL (2004)
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
BP Zambrowicz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney -: Role of pendrin in mineralocorticoid-induced hypertension
JW Verlander et al.
HYPERTENSION (2003)
Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein
I Giménez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect
AL Woo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)
Mutations in the human Na-K-2Cl cotransporter (NKCC2) identified in Bartter syndrome type I consistently result in nonfunctional transporters
PGJF Starremans et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Cation chloride cotransporters interact with the stress-related kinases Ste20-kelated proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
K Piechotta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Liddle's syndrome associated with a point mutation in the extracellular domain of the epithelial sodium channel γ subunit
TP Hiltunen et al.
JOURNAL OF HYPERTENSION (2002)
Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension
PKK Leong et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Primary prevention of hypertension - Clinical and public health advisory from the National High Blood Pressure Education Program
PK Whelton et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)
Renal Na-K-Cl cotransporter NKCC2 in Dahl salt-sensitive rats
M Alvarez-Guerra et al.
JOURNAL OF HYPERTENSION (2002)
Blood pressure responses to small doses of amiloride and spironolactone in normotensive subjects
JH Pratt et al.
HYPERTENSION (2001)
Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics
HL Brooks et al.
JOURNAL OF PHYSIOLOGY-LONDON (2001)
Salt sensitivity, pulse pressure, and death in normal and hypertensive humans
MH Weinberger et al.
HYPERTENSION (2001)
Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome
LA Everett et al.
HUMAN MOLECULAR GENETICS (2001)
Uncompensated polyuria in a mouse model of Bartter's syndrome
N Takahashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Dysfunction of epithelial sodium transport: From human to mouse
O Bonny et al.
KIDNEY INTERNATIONAL (2000)