4.5 Review

Strategies to Prevent Early and Late-Onset Group B Streptococcal Infection via Interventions in Pregnancy

Related references

Note: Only part of the references are listed.
Review Medicine, General & Internal

The 20-valent pneumococcal conjugate vaccine (PCV20): expected added value

Esther Janssens et al.

Summary: This review assesses the potential impact of implementing the investigational 20-valent pneumococcal conjugate vaccine (PCV20) in the vaccination programs of Belgium and Europe. The study finds that PCV20 has the potential to prevent more pneumococcal disease than existing vaccines, but further research is needed to confirm its effectiveness and safety.

ACTA CLINICA BELGICA (2023)

Review Psychology, Developmental

Early Life Antibiotic Exposure and the Subsequent Risk of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis

Hai-ying Yu et al.

Summary: Early life antibiotic exposure is associated with an increased risk of ASD and ADHD, but this association disappears when data from sibling-matched studies are pooled. The statistically significant association between early life antibiotic exposure and ASD or ADHD in later life can be partially explained by unmeasured genetic and familial confounding factors.

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2022)

Editorial Material Immunology

Immunization in pregnancy to protect pregnant people and their newborns against COVID-19

Mahin Delara et al.

EXPERT REVIEW OF VACCINES (2022)

Editorial Material Immunology

Methodology for a correlate of protection for group B Streptococcus: Report from the Bill & Melinda Gates Foundation workshop held on 10 and 11 February 2021

Peter B. Gilbert et al.

Summary: While childhood mortality has decreased globally, newborn mortality remains high. Group B Streptococcus (GBS) disease is a leading cause of newborn mortality, and research has shown the potential for maternal vaccination to protect infants. Several vaccine candidates are currently undergoing clinical trials. Experts discussed considerations and statistical methodologies for establishing a correlate of protection (CoP) for GBS disease.

VACCINE (2022)

Editorial Material Infectious Diseases

The urgent need to recognize and properly address prenatal-onset group B Streptococcus disease

Natalia Silva Costa et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

Article Obstetrics & Gynecology

Effectiveness of oral intake of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on Group B Streptococcus colonization during pregnancy: a midwifery-led double-blind randomized controlled pilot trial

Mary Sharpe et al.

Summary: This study aimed to investigate the effectiveness of oral probiotics in reducing GBS colonization during pregnancy, but the results did not show a significant difference compared to placebo. Further research with a larger, randomized controlled trial is needed to evaluate the efficacy of these two probiotic strains.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE (2021)

Article Infectious Diseases

Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy, non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded, dose-escalation trial

Judith Absalon et al.

Summary: This study evaluated the safety and immunogenicity of a novel hexavalent GBS conjugate vaccine in healthy adults. The vaccine elicited robust and persistent immune responses for all dose levels and formulations, with good tolerability, supporting further evaluation in pregnant women.

LANCET INFECTIOUS DISEASES (2021)

Editorial Material Infectious Diseases

Group B streptococcus vaccines: one step further

Reinhard Berner

LANCET INFECTIOUS DISEASES (2021)

Article Infectious Diseases

Serotype distribution and incidence of invasive early onset and late onset group B streptococcal disease amongst infants in Singapore

Kai-Qian Kam et al.

Summary: The study found that the incidence of LOD remained higher than EOD in the cohort. A GBS vaccine targeting the major causative serotypes identified in the study could potentially reduce the overall burden of GBS disease in the country.

BMC INFECTIOUS DISEASES (2021)

Article Psychiatry

Early life exposure to antibiotics and the risk of mood and anxiety disorders in children and adolescents: A population-based cohort study

Mahin Delara et al.

Summary: This study on 221,139 children born in Manitoba, Canada between 1996 and 2012 found that maternal antibiotic use in pregnancy was significantly associated with an increased risk of mood and anxiety disorders (MADs) in children. However, overall antibiotic exposure in the first three years of life and specific postnatal antibiotic exposures showed varying effects on the risk of MADs, with some even having a protective effect. The associations observed may have been confounded by indication and may not have clinical significance.

JOURNAL OF PSYCHIATRIC RESEARCH (2021)

Article Allergy

Evidence for causal associations between prenatal and postnatal antibiotic exposure and asthma in children, England

Sergio Souza da Cunha et al.

Summary: The study of 12,476 children showed an association between prenatal exposure to antibiotics and postnatal exposure to antibiotics with an increased risk of asthma in children, especially in those exposed postnatally where the risk of asthma increased with the number of prescriptions. The effect was lower among children with mothers of Pakistani ethnicity, and the interaction between prenatal and postnatal exposures was inconclusive. The population attributable risk of postnatal exposure for asthma was 4.6%.

CLINICAL AND EXPERIMENTAL ALLERGY (2021)

Review Immunology

Bacterial and Host Determinants of Group B Streptococcal Vaginal Colonization and Ascending Infection in Pregnancy

Alyssa Brokaw et al.

Summary: Group B streptococcus colonization during pregnancy can lead to adverse outcomes, but there is currently no approved vaccine to prevent GBS infections. Understanding the pathogenesis of GBS disease may help in finding targeted therapeutic strategies to reduce the global burden of GBS infections.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Review Infectious Diseases

Understanding Factors in Group B Streptococcus Late-Onset Disease

Alberto Berardi et al.

Summary: Group B streptococcus (GBS) infection remains a leading cause of sepsis, pneumonia, and meningitis in infants, with early onset cases decreasing due to widespread use of intrapartum antibiotics, leading to late-onset infections as common presentation. The pathogenesis, mode of transmission, and risk factors for LOGBS are unclear, hindering effective prevention efforts.

INFECTION AND DRUG RESISTANCE (2021)

Article Pediatrics

Mortality, neurodevelopmental impairments, and economic outcomes after invasive group B streptococcal disease in early infancy in Denmark and the Netherlands: a national matched cohort study

Erzsebet Horvath-Puho et al.

Summary: This study evaluated the long-term effects of infant invasive Group B Streptococcus (GBS) disease on mortality, neurodevelopmental impairments, and economic outcomes up to adolescence in Denmark and the Netherlands. The findings showed that meningitis was associated with increased mortality at age 5, any iGBS disease increased the risk of NDI at age 10, and children with a history of iGBS disease required more frequent outpatient clinic visits and hospital admissions by age 5.

LANCET CHILD & ADOLESCENT HEALTH (2021)

Review Pediatrics

Vaccination during pregnancy: current and possible future recommendations

Kirsten Maertens et al.

EUROPEAN JOURNAL OF PEDIATRICS (2020)

Article Infectious Diseases

A Vaccine Against Group B Streptococcus: Recent Advances

Clara Carreras-Abad et al.

INFECTION AND DRUG RESISTANCE (2020)

Article Multidisciplinary Sciences

Oral probiotics to reduce vaginal group B streptococcal colonization in late pregnancy

Alex Farr et al.

SCIENTIFIC REPORTS (2020)

Article Immunology

Group B Streptococcus: Trials and Tribulations

Hannah G. Davies et al.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2019)

Article Infectious Diseases

Characterisation of bone and joint infections due to Group B Streptococcus serotype III sequence type 283

Sean W. Ong et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2018)

Article Microbiology

Genetic evidence for a novel variant of the pilus island 1 backbone protein in group B Streptococcus

Sarah Teatero et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2017)

Review Biochemistry & Molecular Biology

Perinatal Group B Streptococcal Infections: Virulence Factors, Immunity, and Prevention Strategies

Jay Vornhagen et al.

TRENDS IN MICROBIOLOGY (2017)

Review Biotechnology & Applied Microbiology

Vaccine development and trials in low and lower-middle income countries: Key issues, advances and future opportunities

Amy Grenham et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2017)

Article Obstetrics & Gynecology

Maternal Immunization With an Investigational Trivalent Group B Streptococcal Vaccine A Randomized Controlled Trial

Gilbert G. G. Donders et al.

OBSTETRICS AND GYNECOLOGY (2016)

Article Multidisciplinary Sciences

Structure and Assembly of Group B Streptococcus Pilus 2b Backbone Protein

Roberta Cozzi et al.

PLOS ONE (2015)

Review Microbiology

Early-Onset Neonatal Sepsis

Kari A. Simonsen et al.

CLINICAL MICROBIOLOGY REVIEWS (2014)

Article Nursing

Feasibility of Oral Prenatal Probiotics against Maternal Group B Streptococcus Vaginal and Rectal Colonization

Lisa Hanson et al.

JOGNN-JOURNAL OF OBSTETRIC GYNECOLOGIC AND NEONATAL NURSING (2014)

Article Immunology

Maternal Antibody at Delivery Protects Neonates From Early Onset Group B Streptococcal Disease

Carol J. Baker et al.

JOURNAL OF INFECTIOUS DISEASES (2014)

Article Obstetrics & Gynecology

The Prevention of Early-Onset Neonatal Group B Streptococcal Disease

Deborah Money et al.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA (2013)

Review Immunology

T cell-independent B cell memory

Thierry Defrance et al.

CURRENT OPINION IN IMMUNOLOGY (2011)

Review Medicine, General & Internal

Serotype replacement in disease after pneumococcal vaccination

Daniel M. Weinberger et al.

LANCET (2011)

Article Pediatrics

Horizontal transmission of group B streptococcus in a neonatal intensive care unit

Julia Morinis et al.

PAEDIATRICS & CHILD HEALTH (2011)

Review Immunology

How Bacterial Carbohydrates Influence the Adaptive Immune System

Fikri Y. Avci et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 28 (2010)

Article Biochemistry & Molecular Biology

Recent advances in understanding the molecular basis of group B Streptococcus virulence

Heather C. Maisey et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2008)

Article Medicine, General & Internal

Probiotics: sorting the evidence from the myths

Mimi Pham et al.

MEDICAL JOURNAL OF AUSTRALIA (2008)

Review Obstetrics & Gynecology

Consequences of prophylaxis for group B streptococcal infections of the neonate

Robert S. Baltimore

SEMINARS IN PERINATOLOGY (2007)