Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients

Toxoplasma gondii is a worldwide distributed protozoan parasite. This apicomplexan parasite infects one-third of the population worldwide, causing toxoplasmosis, considered one of the neglected parasitic infections. In healthy humans, most infections are asymptomatic. However, in immunocompromised patients, the course of the disease can be life-threatening. Human immunodeficiency virus (HIV)-infected patients have a very high burden of Toxoplasma gondii co-infection. Thus, it is essential to use modern, sensitive, and specific methods to properly monitor the course of toxoplasmosis in immunodeficient patients.

Automated summary

Toxoplasma gondii is a globally distributed protozoan parasite that infects a third of the world's population, causing toxoplasmosis which is considered a neglected parasitic infection. Most infections in healthy individuals are asymptomatic, but the disease can be life-threatening in immunocompromised patients. HIV-infected patients have a high burden of co-infection with Toxoplasma gondii, highlighting the need for modern, sensitive, and specific methods to monitor the course of toxoplasmosis in immunodeficient patients.