Novel resorbable bone wax containing β-TCP and starch microspheres for accelerating bone hemostasis and promoting regeneration

Traditional non-resorbable bone wax has been used in clinical surgery for more than 100 years. However, residual bone wax has been proven to cause numerous complications. In this study, a novel resorbable bone wax was designed to overcome the disadvantages of traditional non-resorbable bone wax. Alkylene oxide copolymers were used as the main component of resorbable bone wax; additionally, beta-tricalcium phosphate and starch microspheres were added to enhance bone regeneration and hemostatic ability. This novel resorbable bone wax has a high potential for clinical translation and is expected to be developed as a substitute for traditional bone wax.

Automated summary

Traditional non-resorbable bone wax has been used for over 100 years in clinical surgery, but it can lead to various complications. To address this issue, a novel resorbable bone wax composed of alkylene oxide copolymers, beta-tricalcium phosphate, and starch microspheres was developed. This new material has the potential to be a substitute for traditional bone wax and can enhance bone regeneration and hemostatic ability.