Comprehensive personalized ankle joint shape analysis of children with cerebral palsy from pediatric MRI

Cerebral palsy, a common physical disability in childhood, often causes abnormal patterns of movement and posture. To better understand the pathology and improve rehabilitation of patients, a comprehensive bone shape analysis approach is proposed in this article. First, a group analysis is performed on a clinical MRI dataset using two state-of-the-art shape analysis methods: ShapeWorks and a voxel-based method relying on Advanced Normalization Tools (ANTs) registration. Second, an analysis of three bones of the ankle is done to provide a complete view of the ankle joint. Third, a bone shape analysis is carried out at subject level to highlight variability patterns for personnalized understanding of deformities.

Automated summary

This article proposes a comprehensive bone shape analysis approach to better understand the abnormal movement and posture issues in patients with cerebral palsy. By performing group analysis and individual analysis on a clinical MRI dataset, as well as analyzing three bones of the ankle, the authors aim to provide personalized understanding of bone deformities.