Journal
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Volume 10, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fcell.2022.1051306
Keywords
hepatocellular carcinoma; long noncoding RNA; gene expression regulation; biomarker; diagnosis and therapy
Categories
Funding
- Medicine and Health Care Science and Technology Development Plan Projects Foundation of Shandong Province
- [202003100622]
Ask authors/readers for more resources
lncRNAs may play key roles in hepatocellular carcinoma (HCC) and have the potential to serve as diagnostic and therapeutic biomarkers.
Hepatocellular carcinoma (HCC) is the most frequent and deadly type of liver cancer. While the underlying molecular mechanisms are poorly understood, it is documented that lncRNAs may play key roles. Many HCC-associated lncRNAs have been linked to HBV and HCV infection, mediating gene expression, cell growth, development, and death. Studying the regulatory mechanisms and biological functions of HCC-related lncRNAs will assist our understanding of HCC pathogenesis as well as its diagnosis and management. Here, we address the potential of dysregulated lncRNAs in HCC as diagnostic and therapeutic biomarkers, and we evaluate the oncogenic or tumor-suppressive properties of these lncRNAs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
