Journal
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
Volume 309, Issue 2, Pages 517-523Publisher
SPRINGER
DOI: 10.1007/s10967-015-4671-7
Keywords
Quinazoline derivatives; Biodistribution; F-18; PET
Funding
- National Natural Science Foundation of China [21071022]
- Fundamental Research Funds for the Central Universities
Ask authors/readers for more resources
In this study, three F-18-labeled crown ether fused anilinoquinazoline derivatives ([F-18]11a-c) were synthesized and evaluated as potential tumor imaging probes. The biodistribution results of [F-18]11b were good. Compared with [F-18]-fludeoxyglucose and l-[F-18]-fluoroethyltyrosine in the same animal model, [F-18]11b had better tumor/brain, tumor/muscle, and tumor/blood uptake ratios. Overall, these results suggest that [F-18]11b is promising as a tumor imaging agent for positron emission tomography.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
