4.5 Article

Brain single cell transcriptomic profiles in episodic memory phenotypes associated with temporal lobe epilepsy

Related references

Note: Only part of the references are listed.
Review Neurosciences

Molecular mechanism of hippocampal long-term potentiation-Towards multiscale understanding of learning and memory

Yasunori Hayashi

Summary: Long-term potentiation (LTP) of synaptic transmission is considered as the cellular basis of learning and memory. Activation of NMDA-R triggers the movement of AMPA-R and other proteins, while dendritic spine expands with actin modulation. CaMKII sustains long-term signaling by forming a reciprocally-activating complex with its substrate proteins. Additionally, activated CaMKII can condense at the synapse through liquid-liquid phase separation, increasing binding capacity and capturing newly synthesized proteins.

NEUROSCIENCE RESEARCH (2022)

Review Behavioral Sciences

The Intriguing Contribution of Hippocampal Long-Term Depression to Spatial Learning and Long-Term Memory

Martin Stacho et al.

Summary: Long-term potentiation (LTP) and long-term depression (LTD) are cellular mechanisms related to learning and memory. LTD has a specific role in hippocampus-dependent associative learning and information encoding, reducing excitatory synapses and restricting the effects of LTP. It acts in conjunction with LTP to contribute to learning.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2022)

Article Multidisciplinary Sciences

Single-cell transcriptomic analysis of Alzheimer's disease

Hansruedi Mathys et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

Comprehensive Integration of Single-Cell Data

Tim Stuart et al.

Article Neurosciences

Synaptogenic pathways

Peri T. Kurshan et al.

CURRENT OPINION IN NEUROBIOLOGY (2019)

Article Biotechnology & Applied Microbiology

scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data

Jose Alquicira-Hernandez et al.

GENOME BIOLOGY (2019)

Article Behavioral Sciences

Sex differences in verbal and nonverbal learning before and after temporal lobe epilepsy surgery

Justus Berger et al.

EPILEPSY & BEHAVIOR (2017)

Article Clinical Neurology

Mechanisms of memory impairment in epilepsy depend on age at disease onset

Genevieve Rayner et al.

NEUROLOGY (2016)

Article Neurosciences

Molecular regulation of synaptogenesis during associative learning and memory

Thomas J. Nelson et al.

BRAIN RESEARCH (2015)

Article Cell Biology

Structural Components of Synaptic Plasticity and Memory Consolidation

Craig H. Bailey et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)

Review Behavioral Sciences

Genetics of cognition in epilepsy

Robyn M. Busch et al.

EPILEPSY & BEHAVIOR (2014)

Article Clinical Neurology

The influence of seizure frequency on anterograde and remote memory in mesial temporal lobe epilepsy

Virginie Voltzenlogel et al.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2014)

Article Behavioral Sciences

Comparing patients' and practitioners' views on epilepsy concerns: A call to address memory concerns

James W. McAuley et al.

EPILEPSY & BEHAVIOR (2010)

Review Clinical Neurology

Brain plasticity mechanisms and memory: A party of four

Elodie Bruel-Jungerman et al.

NEUROSCIENTIST (2007)

Article Clinical Neurology

Cognitive prognosis in chronic temporal lobe epilepsy

Bruce P. Hermann et al.

ANNALS OF NEUROLOGY (2006)

Article Biochemistry & Molecular Biology

KEGG: Kyoto Encyclopedia of Genes and Genomes

M Kanehisa et al.

NUCLEIC ACIDS RESEARCH (2000)