Related references
Note: Only part of the references are listed.Candidates for Repurposing as Anti-Virulence Agents Based on the Structural Profile Analysis of Microbial Collagenase Inhibitors
Georgiana Nitulescu et al.
PHARMACEUTICS (2022)
Identifying FAAH Inhibitors as New Therapeutic Options for the Treatment of Chronic Pain through Drug Repurposing
Anca Zanfirescu et al.
PHARMACEUTICALS (2022)
A new era for the design of TRPV1 antagonists and agonists with the use of structural information and molecular docking of capsaicin-like compounds
Julio Caballero
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2022)
Agomelatine attenuates calcium signaling and apoptosis via the inhibition of TRPV1 channel in the hippocampal neurons of rats with chronic mild stress depression model
Gulin Ozdamar Unal et al.
BEHAVIOURAL BRAIN RESEARCH (2022)
Identification of a Partial and Selective TRPV1 Agonist CPIPC for Alleviation of Inflammatory Pain
Liying Dong et al.
MOLECULES (2022)
Melatonin and Selenium Suppress Docetaxel-Induced TRPV1 Activation, Neuropathic Pain and Oxidative Neurotoxicity in Mice
Kemal Ertilav et al.
BIOLOGICAL TRACE ELEMENT RESEARCH (2021)
A practical guide to large-scale docking
Brian J. Bender et al.
NATURE PROTOCOLS (2021)
Dual regulation of TRPV1 channels by phosphatidylinositol via functionally distinct binding sites
Aysenur Torun Yazici et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
Kaihua Zhang et al.
CELL (2021)
Effects of Venlafaxine, Risperidone and Febuxostat on Cuprizone-Induced Demyelination, Behavioral Deficits and Oxidative Stress
Dragos Paul Mihai et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
TRPV1-Targeted Drugs in Development for Human Pain Conditions
Mircea Iftinca et al.
DRUGS (2021)
Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel
Wentong Long et al.
JOURNAL OF PHYSIOLOGY-LONDON (2020)
Drug discovery with explainable artificial intelligence
Jose Jimenez-Luna et al.
NATURE MACHINE INTELLIGENCE (2020)
The silent epidemic of chronic pain in older adults
Anthony F. Domenichiello et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2019)
Optimizing Pain Control During the Opioid Epidemic
Calista M. Harbaugh et al.
SURGICAL CLINICS OF NORTH AMERICA (2019)
Computational Drug Repurposing Algorithm Targeting TRPA1 Calcium Channel as a Potential Therapeutic Solution for Multiple Sclerosis
Dragos Paul Mihai et al.
PHARMACEUTICS (2019)
Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications
Guillem Jubete et al.
MOLECULES (2019)
DrugBank 5.0: a major update to the DrugBank database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
Detection and modulation of capsaicin perception in the human oral cavity
Gregory Smutzer et al.
PHYSIOLOGY & BEHAVIOR (2018)
Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type-2 diabetes mellitus
Liang-Chen Wang et al.
MEDICINE (2018)
Agomelatine: a new opportunity to reduce neuropathic pain-preclinical evidence
Chouki Chenaf et al.
PAIN (2017)
Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms
Taliha H. Aydin et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2016)
The effects of intra-articular resiniferatoxin on monosodium iodoacetate-induced osteoarthritic pain in rats
Youngkyung Kim et al.
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY (2016)
Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses
Victor Fattori et al.
MOLECULES (2016)
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
Yuan Gao et al.
NATURE (2016)
Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain
Marco Sisignano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Data Warrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis
Thomas Sander et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)
Telmisartan inhibits hyperalgesia and inflammatory progression in a diabetic neuropathic pain model of Wistar rats
Salim S. Al-Rejaie et al.
NEUROSCIENCES (2015)
Serotonergic modulation in neuropathy induced by oxaliplatin: Effect on the 5HT2C receptor
Daniela Baptista-de-Souza et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Synthesis and Pharmacological Evaluation of a series of the Agomelatine Analogues as Melatonin MT1/MT2 Agonist and 5-HT2C Antagonist
Mohamed Ettaoussi et al.
CHEMMEDCHEM (2013)
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
Maofu Liao et al.
NATURE (2013)
EVIDENCE FOR THE PARTICIPATION OF PERIPHERAL 5-HT2A, 5-HT2B, AND 5HT2C RECEPTORS IN FORMALIN-INDUCED SECONDARY MECHANICAL ALLODYNIA AND HYPERALGESIA
C. Cervantes-Duran et al.
NEUROSCIENCE (2013)
Repaglinide A Review of Its Use in Type 2 Diabetes Mellitus
Lesley J. Scott
DRUGS (2012)
Targeting TRPV1 for pain relief: limits, losers and laurels
Arpad Szallasi et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)
ChEMBL: a large-scale bioactivity database for drug discovery
Anna Gaulton et al.
NUCLEIC ACIDS RESEARCH (2012)
Multisteric TRPV1 nocisensor: a target for analgesics
Janos Szolcsanyi et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch
P. Anand et al.
BRITISH JOURNAL OF ANAESTHESIA (2011)
Exploring the potential of telmisartan in chronic constriction injury-induced neuropathic pain in rats
Amteshwar Singh Jaggi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Scaffold Diversity of Exemplified Medicinal Chemistry Space
Sarah R. Langdon et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
PaDEL-Descriptor: An Open Source Software to Calculate Molecular Descriptors and Fingerprints
Chun Wei Yap
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
Open Babel: An open chemical toolbox
Noel M. O'Boyle et al.
JOURNAL OF CHEMINFORMATICS (2011)
Antinociceptive desensitizing actions of TRPV1 receptor agonists capsaicin, resiniferatoxin and N-oleoyldopamine as measured by determination of the noxious heat and cold thresholds in the rat
Kata Bolcskei et al.
EUROPEAN JOURNAL OF PAIN (2010)
Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate
Karel-Martijn Kalff et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Analgesic potential of TRPV1 antagonists
Philip R. Kym et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks
Gilbert Y. Wong et al.
BRAIN RESEARCH REVIEWS (2009)
Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway
Martin J. Gunthorpe et al.
DRUG DISCOVERY TODAY (2009)
Beyond the monoaminergic hypothesis: Agomelatine, a new antidepressant with an innovative mechanism of action
Siegfried Kasper et al.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2009)
TRPV1: A target for next generation analgesics
Louis S. Premkumar et al.
CURRENT NEUROPHARMACOLOGY (2008)
Agomelatine: A novel mechanism of antidepressant action involving the melatonergic and the serotonergic system
Luis San et al.
EUROPEAN PSYCHIATRY (2008)
Flexophore, a new versatile 3D pharmacophore descriptor that considers molecular flexibility
Modest von Korff et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)
Oral and spinal melatonin reduces tactile allodynia in rats via activation of MT2 and opioid receptors
Monica Ambriz-Tututi et al.
PAIN (2007)
TRPV1: a therapeutic target for novel analgesic drugs?
Arpad Szallasi et al.
TRENDS IN MOLECULAR MEDICINE (2006)
A review of telmisartan in the treatment of hypertension: blood pressure control in the early morning hours
Philippe Gosse
VASCULAR HEALTH AND RISK MANAGEMENT (2006)
Analgesic effects of capsazepine and resiniferatoxin on bone cancer pain in mice
L Menédez et al.
NEUROSCIENCE LETTERS (2006)
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats
P Honore et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain
JR Ghilardi et al.
JOURNAL OF NEUROSCIENCE (2005)
Biochemical pharmacology of the vanilloid receptor TRPV1 - An update
DN Cortright et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice
G Pethö et al.
PAIN (2004)
N-(4-tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl) tetrahydropyrazine-1(2H)-carbox-amide(BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties:: II.: In vivo characterization in rat models of inflammatory and neuropathic pain
JD Pomonis et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Selective and long-lasting neural blockade with resiniferatoxin prevents inflammatory pain hypersensitivity
I Kissin et al.
ANESTHESIA AND ANALGESIA (2002)
Interaction between vanilloid and glutamate receptors in the central modulation of nociception
E Palazzo et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
JB Davis et al.
NATURE (2000)
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
MJ Caterina et al.
SCIENCE (2000)
Selective MT2 melatonin receptor antagonist blocks melatonin-induced antinociception in rats
CX Yu et al.
NEUROSCIENCE LETTERS (2000)
Share Paper
