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Biomaterials Based on Organic Polymers and Layered Double Hydroxides Nanocomposites: Drug Delivery and Tissue Engineering

PHARMACEUTICS (2023)

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3D additive manufactured composite scaffolds with antibiotic-loaded lamellar fillers for bone infection prevention and tissue regeneration

Maria Camara-Torres et al.

Summary: This study demonstrates the fabrication of dual functionality 3D scaffolds via high temperature melt extrusion for bone regeneration and infection prevention. The scaffolds maintain the antibiotic activity at high temperatures and do not impair human mesenchymal stromal cells osteogenic differentiation.

BIOACTIVE MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Layered Double Hydroxide Modified Bone Cement Promoting Osseointegration via Multiple Osteogenic Signal Pathways

Yingjie Wang et al.

Summary: In this study, MgAl-layered double hydroxide (LDH) microsheets modified PMMA (PMMA&LDH) bone cement with superior osseointegration performance has been synthesized. The PMMA&LDH showed improved temperature and mechanical performance compared to conventional PMMA and PMMA&COL-I. In vivo experiments demonstrated the superior osteogenic ability of PMMA&LDH, suggesting its potential application in orthopedic surgeries to promote bone growth.

ACS NANO (2021)

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Article Biochemistry & Molecular Biology

Facile preparation of layered double hydroxide (LDH)-alginate beads as sustainable system for the triggered release of diclofenac: Effect of pH and temperature on release rate

Gianluca Viscusi et al.

Summary: This paper explores the facile preparation of alginate beads encapsulating layered double hydroxide (LDH) intercalated with diclofenac sodium for drug delivery systems. The study evaluates the effect of LDH carrier, release kinetics of diclofenac at different pH and temperatures, and the fabrication of a sustainable composite characterized by a triggered drug release rate. Empirical relationships correlating the drug diffusion as a function of temperature and pH were also extrapolated.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Chemistry, Multidisciplinary

Heat/pH-boosted release of 5-fluorouracil and albumin-bound paclitaxel from Cu-doped layered double hydroxide nanomedicine for synergistical chemo-photo-therapy of breast cancer

Jianping Liu et al.

Summary: A novel nanomedicine has been developed for combination breast cancer therapy, which shows high efficacy in nearly eliminating tumors with minimal side effects.

JOURNAL OF CONTROLLED RELEASE (2021)

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Review Materials Science, Multidisciplinary

Structure and Applications of Pectin in Food, Biomedical, and Pharmaceutical Industry: A Review

Cariny Maria Polesca Freitas et al.

Summary: Pectin is a biocompatible polysaccharide with intrinsic biological activity that can exhibit different structures depending on its source or extraction method. Its extraction from various industrial by-products offers a green option for valorizing agro-industrial residues, producing high commercial value products. Pectin is versatile and can be modified for numerous applications in food, agriculture, drugs, and biomedicine, showing enhanced functional properties and bioactivities in recent advances.

COATINGS (2021)

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Review Pharmacology & Pharmacy

Eudragit(R): A Versatile Family of Polymers for Hot Melt Extrusion and 3D Printing Processes in Pharmaceutics

Juliana dos Santos et al.

Summary: Eudragit polymers, widely used in pharmaceuticals, offer versatility in chemical composition and have been utilized in various drug delivery systems. Eudragit E is commonly used for immediate release systems, while Eudragit RS and Eudragit L100-55 are preferred for controlled and delayed release systems, respectively. Their use in processes like HME and 3D printing showcases the numerous possibilities for innovative drug release systems.

PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Preparation and application of layered double hydroxide nanosheets

Yaping Zhang et al.

Summary: Layered double hydroxides (LDH) with unique structure and excellent properties have been widely studied in catalysts, polymer/LDH nanocomposites, supercapacitors, and more. Recent developments in LDH exfoliation methods and direct synthesis of LDH single-layer nanosheets have opened up new opportunities in various applications.

RSC ADVANCES (2021)

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Review Cell & Tissue Engineering

On the road to smart biomaterials for bone research: definitions, concepts, advances, and outlook

Carolina Montoya et al.

Summary: The demand for biomaterials to promote repair, replacement, or restoration of hard and soft tissues is increasing due to population aging. This review redefines the concept of "Smart Biomaterial" and discusses recent advances in hard tissue repair and regeneration. It proposes four degrees of smartness and surveys the applications of smart biomaterials in hard tissues, along with discussing limitations in translation from basic research to clinical utilization.

BONE RESEARCH (2021)

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Article Nanoscience & Nanotechnology

Skin-Inspired Multifunctional Luminescent Hydrogel Containing Layered Rare-Earth Hydroxide with 3D Printability for Human Motion Sensing

Yuanyuan Ren et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Engineering, Biomedical

Multifunctional carboxymethyl chitosan derivatives-layered double hydroxide hybrid nanocomposites for efficient drug delivery to the posterior segment of the eye

Yanyan Wang et al.

ACTA BIOMATERIALIA (2020)

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Review Polymer Science

Ionotropic gelation method in the synthesis of nanoparticles/microparticles for biomedical purposes

Seidy Pedroso-Santana et al.

POLYMER INTERNATIONAL (2020)

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Review Pharmacology & Pharmacy

Antibodies against polyethylene glycol in human blood: A literature review

Lu Hong et al.

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2020)

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Article Polymer Science

Multi-Fold Enhancement in Compressive Properties of Polystyrene Foam Using Pre-delaminated Stearate Functionalized Layer Double Hydroxides

Emmanuel O. Ogunsona et al.

POLYMERS (2020)

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Article Polymer Science

Design of 3D multi-layered electrospun membranes embedding iron-based layered double hydroxide for drug storage and control of sustained release

Mariana P. Figueiredo et al.

EUROPEAN POLYMER JOURNAL (2020)

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Review Polymer Science

An Insight into the Structural Diversity and Clinical Applicability of Polyurethanes in Biomedicine

Laura-Cristina Rusu et al.

POLYMERS (2020)

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Review Biochemistry & Molecular Biology

New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers

Cornelia Vasile et al.

MOLECULES (2020)

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Review Crystallography

Morphology, Thermal Stability, and Flammability Properties of Polymer-Layered Double Hydroxide (LDH) Nanocomposites: A Review

Mokgaotsa Jonas Mochane et al.

CRYSTALS (2020)

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Review Chemistry, Physical

Recent innovations in functionalized layered double hydroxides: Fabrication, characterization, and industrial applications

Shadpour Mallakpour et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2020)

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Article Polymer Science

Fabrication of functionalized layered double hydroxide/chitosan nanocomposite with dual responsive drug release for the targeted therapy of breast cancer

T. S. Anirudhan et al.

EUROPEAN POLYMER JOURNAL (2020)

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Review Chemistry, Multidisciplinary

A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering

Huong D. N. Tran et al.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2020)

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Review Polymer Science

Scaffolds for Wound Healing Applications

Irina Negut et al.

POLYMERS (2020)

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Review Crystallography

Effect of LDHs and Other Clays on Polymer Composite in Adsorptive Removal of Contaminants: A Review

Maleshoane Mohapi et al.

CRYSTALS (2020)

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Review Biotechnology & Applied Microbiology

Innovative Options for Bone Metastasis Treatment: An Extensive Analysis on Biomaterials-Based Strategies for Orthopedic Surgeons

Ania Naila Guerrieri et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Article Pharmacology & Pharmacy

Polymer/Iron-Based Layered Double Hydroxides as Multifunctional Wound Dressings

Mariana Pires Figueiredo et al.

PHARMACEUTICS (2020)

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Article Chemistry, Multidisciplinary

Hydrotalcite-PLGA composite nanoparticles for loading and delivery of danshensu

Lihui Pu et al.

RSC ADVANCES (2020)

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Article Chemistry, Physical

The peculiar dissolution behaviour of Piretanide hosted in layered double hydroxides

Marianna Guagliano et al.

APPLIED CLAY SCIENCE (2020)

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Article Chemistry, Multidisciplinary

Fabrication of bionanocomposite based on LDH using biopolymer of gum arabic and chitosan-coating for sustained drug-release

Milad Abniki et al.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY (2020)

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Review Chemistry, Physical

2D Layered Double Hydroxide Nanoparticles: Recent Progress toward Preclinical/Clinical Nanomedicine

Zhenbang Cao et al.

SMALL METHODS (2020)

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Article Chemistry, Inorganic & Nuclear

Surface modification of aqueous miscible organic layered double hydroxides (AMO-LDHs)

Chunping Chen et al.

DALTON TRANSACTIONS (2020)

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Review Engineering, Biomedical

3D printing of bone tissue engineering scaffolds

Chong Wang et al.

BIOACTIVE MATERIALS (2020)

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Article Chemistry, Physical

Determination of half maximal inhibitory concentration of CaAl layered double hydroxide on cancer cells and its role in the apoptotic pathway

Arnab Bhattacharjee et al.

APPLIED CLAY SCIENCE (2019)

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Article Chemistry, Physical

MODIFYING LAYERED DOUBLE HYDROXIDE NANOPARTICLES FOR TUMOR IMAGING AND THERAPY

Li Li et al.

CLAYS AND CLAY MINERALS (2019)

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Article Chemistry, Physical

Bionanocomposites based on cationic and anionic layered clays as controlled release devices of amoxicillin

Ediana P. Rebitski et al.

APPLIED CLAY SCIENCE (2019)

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Review Chemistry, Physical

Layered double hydroxide based bionanocomposites

Aniruddha Chatterjee et al.

APPLIED CLAY SCIENCE (2019)

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Article Materials Science, Biomaterials

Highly porous polycaprolactone scaffolds doped with calcium silicate and dicalcium phosphate dihydrate designed for bone regeneration

Maria Giovanna Gandolfi et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

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Article Biochemistry & Molecular Biology

Green encapsulation of LDH(Zn/Al)-5-Fu with carboxymethyl cellulose biopolymer; new nanovehicle for oral colorectal cancer treatment

Malihe Pooresmaeil et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

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Article Chemistry, Physical

Alginate-chitosan coated layered double hydroxide nanocomposites for enhanced oral vaccine delivery

Xinying Yu et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

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Article Engineering, Biomedical

Construction of a biodegradable, versatile nanocarrier for optional combination cancer therapy

Jia Wen et al.

ACTA BIOMATERIALIA (2019)

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Article Chemistry, Physical

Sol-Gel Synthesis and Characterization of Coatings of Mg-Al Layered Double Hydroxides

A. Smalenskaite et al.

MATERIALS (2019)

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Review Chemistry, Multidisciplinary

Degradability and Clearance of Inorganic Nanoparticles for Biomedical Applications

Guangbao Yang et al.

ADVANCED MATERIALS (2019)

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Article Biochemistry & Molecular Biology

Tissue Concentrations of Zinc, Iron, Copper, and Magnesium During the Phases of Full Thickness Wound Healing in a Rodent Model

Vincent Coger et al.

BIOLOGICAL TRACE ELEMENT RESEARCH (2019)

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Article Materials Science, Composites

Preparation, Performance, and Kinetics of Poly(Lactic-Acid)/Amidated Benzoic Acid Intercalated Layered Double Hydroxides Nanocomposites by Reactive Extrusion Process

Zhongxing Geng et al.

POLYMER COMPOSITES (2019)

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Article Multidisciplinary Sciences

A general aerosol-assisted biosynthesis of functional bulk nanocomposites

Qing-Fang Guan et al.

NATIONAL SCIENCE REVIEW (2019)

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Article Nanoscience & Nanotechnology

Some basic aspects of polymer nanocomposites: A critical review

Shaoyun Fu et al.

NANO MATERIALS SCIENCE (2019)

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Review Materials Science, Biomaterials

Layered double hydroxide nanostructures and nanocomposites for biomedical applications

Li Yan et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Review Engineering, Biomedical

Key terminology in biomaterials and biocompatibility

Laleh Ghasemi-Mobarakeh et al.

CURRENT OPINION IN BIOMEDICAL ENGINEERING (2019)

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Article Nanoscience & Nanotechnology

Mannose-conjugated layered double hydroxide nanocomposite for targeted siRNA delivery to enhance cancer therapy

Li Li et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

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Article Engineering, Chemical

Quaternized polysulfone-based nanocomposite membranes and improved properties by intercalated layered double hydroxide

Na Liang et al.

POLYMER ENGINEERING AND SCIENCE (2018)

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Article Engineering, Biomedical

Mg-Al and Zn-Al Layered Double Hydroxides Promote Dynamic Expression of Marker Genes in Osteogenic Differentiation by Modulating Mitogen-Activated Protein Kinases

Ha Ram Kang et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Nanoscience & Nanotechnology

Brain Targeting Delivery Facilitated by Ligand-Functionalized Layered Double Hydroxide Nanoparticles

Weiyu Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Review Pharmacology & Pharmacy

Engineering nanomaterials to overcome the mucosal barrier by modulating surface properties

Lei Wu et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

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Article Chemistry, Multidisciplinary

Monolayer Nanosheets with an Extremely High Drug Loading toward Controlled Delivery and Cancer Theranostics

Liuqi Peng et al.

ADVANCED MATERIALS (2018)

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Review Chemistry, Physical

Layered double hydroxides: A brief review from fundamentals to application as evolving biomaterials

Geetanjali Mishra et al.

APPLIED CLAY SCIENCE (2018)

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Article Engineering, Biomedical

Novel theranostic nanoplatform for complete mice tumor elimination via MR imaging-guided acid-enhanced photothermo-/chemo-therapy

Bei Li et al.

BIOMATERIALS (2018)

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Article Engineering, Biomedical

Hydrotalcite monolayer toward high performance synergistic dual-modal imaging and cancer therapy

Xuan Mei et al.

BIOMATERIALS (2018)

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Article Chemistry, Multidisciplinary

Interactions between Biological Cells and Layered Double Hydroxides: Towards Functional Materials

Claude Forano et al.

CHEMICAL RECORD (2018)

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Article Chemistry, Multidisciplinary

Building Up Functional Bionanocomposites from the Assembly of Clays and Biopolymers

Ana C. S. Alcantara et al.

CHEMICAL RECORD (2018)

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Review Chemistry, Multidisciplinary

2D Nanostructured Metal Hydroxides with Gene Delivery and Theranostic Functions; A Comprehensive Review

Goeun Choi et al.

CHEMICAL RECORD (2018)

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Article Chemistry, Inorganic & Nuclear

Ni-Co layered double hydroxide on carbon nanorods and graphene nanoribbons derived from MOFs for supercapacitors

Hongxing Jin et al.

DALTON TRANSACTIONS (2018)

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Review Pharmacology & Pharmacy

Recent advance of nanoparticle-based topical drug delivery to the posterior segment of the eye

Yanyan Wang et al.

EXPERT OPINION ON DRUG DELIVERY (2018)

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Review Engineering, Chemical

Electrospraying an enabling technology for pharmaceutical and biomedical applications: A review

Sunil Kumar Boda et al.

JOURNAL OF AEROSOL SCIENCE (2018)

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Article Chemistry, Physical

Enhanced colloidal stability and protein resistance of layered double hydroxide nanoparticles with phosphonic acid-terminated PEG coating for drug delivery

Zhenbang Cao et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2018)

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Review Polymer Science

Recent advances and remaining challenges for polymeric nanocomposites in healthcare applications

Sandeep Kumar et al.

PROGRESS IN POLYMER SCIENCE (2018)

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Review Chemistry, Multidisciplinary

Materials Nanoarchitectonics Using 2D Layered Materials: Recent Developments in the Intercalation Process

Danial Sangian et al.

SMALL (2018)

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Article Chemistry, Analytical

Confinement of carbon dots localizing to the ultrathin layered double hydroxides toward simultaneous triple-mode bioimaging and photothermal therapy

Yangziwan Weng et al.

TALANTA (2018)

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Article Chemistry, Multidisciplinary

A bottom-up synthesis of rare-earth-hydrotalcite monolayer nanosheets toward multimode imaging and synergetic therapy

Xuan Mei et al.

CHEMICAL SCIENCE (2018)

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Article Multidisciplinary Sciences

Nano-photosensitizer based on layered double hydroxide and isophthalic acid for singlet oxygenation and photodynamic therapy

Rui Gao et al.

NATURE COMMUNICATIONS (2018)

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Review Chemistry, Physical

Nanocomposites Based on Biodegradable Polymers

Ilaria Armentano et al.

MATERIALS (2018)

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Article Engineering, Biomedical

Excitation-Dependent Theranostic Nanosheet for Cancer Treatment

Shanyue Guan et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Materials Science, Biomaterials

Facile synthesis of pH-responsive doxorubicin-loaded layered double hydroxide for efficient cancer therapy

Abdul Hakeem et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Article Materials Science, Biomaterials

Smart Biomaterials: Recent Advances and Future Directions

Piotr S. Kowalski et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

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Review Polymer Science

Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review

Salima T. Minzanova et al.

POLYMERS (2018)

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Article Chemistry, Multidisciplinary

Biodegradable 2D Fe-Al Hydroxide for Nanocatalytic Tumor-Dynamic Therapy with Tumor Specificity

Zhenbang Cao et al.

ADVANCED SCIENCE (2018)

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Article Dermatology

Immunology of Wound Healing

Samantha Ellis et al.

CURRENT DERMATOLOGY REPORTS (2018)

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Article Chemistry, Multidisciplinary

Iron-Based Layered Double Hydroxide Implants: Potential Drug Delivery Carriers with Tissue Biointegration Promotion and Blood Microcirculation Preservation

Mariana P. Figueireclo et al.

ACS OMEGA (2018)

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Review Biochemistry & Molecular Biology

Engineering liposomal nanoparticles for targeted gene therapy

C. Zylberberg et al.

GENE THERAPY (2017)

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Review Nanoscience & Nanotechnology

High drug-loading nanomedicines: progress, current status, and prospects

Shihong Shen et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

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Article Nanoscience & Nanotechnology

Multifunctional organic-inorganic hybrid nanoparticles and nanosheets based on chitosan derivative and layered double hydroxide: cellular uptake mechanism and application for topical ocular drug delivery

Huibo Chi et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

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Review Materials Science, Multidisciplinary

Electrospun porous nanofibers for electrochemical energy storage

Zhi Li et al.

JOURNAL OF MATERIALS SCIENCE (2017)

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Review Materials Science, Biomaterials

A review of drug release mechanisms from nanocarrier systems

Chizhu Ding et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Review Materials Science, Biomaterials

Electrospun nanofibers for wound healing

Minghuan Liu et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Article Chemistry, Multidisciplinary

An NIR-sensitive layered supramolecular nanovehicle for combined dual-modal imaging and synergistic therapy

Shanyue Guan et al.

NANOSCALE (2017)

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Article Chemistry, Multidisciplinary

MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration

Yi-Xuan Chen et al.

NANOSCALE (2017)

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Article Chemistry, Multidisciplinary

Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications

Suzana Hamdan et al.

ACS CENTRAL SCIENCE (2017)

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Review Nanoscience & Nanotechnology

Rotary jet spinning review - a potential high yield future for polymer nanofibers

James J. Rogalski et al.

NANOCOMPOSITES (2017)

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Article Engineering, Biomedical

Nanolayered hybrid mediates synergistic co-delivery of ligand and ligation activator for inducing stem cell differentiation and tissue healing

Heemin Kang et al.

BIOMATERIALS (2017)

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Review Chemistry, Multidisciplinary

Preparation of two dimensional layered double hydroxide nanosheets and their applications

Jingfang Yu et al.

CHEMICAL SOCIETY REVIEWS (2017)

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Article Nanoscience & Nanotechnology

A Novel Type of Aqueous Dispersible Ultrathin-Layered Double Hydroxide Nanosheets for in Vivo Bioimaging and Drug Delivery

Li Yan et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Article Chemistry, Multidisciplinary

Manganese-Based Layered Double Hydroxide Nanoparticles as a T1-MRI Contrast Agent with Ultrasensitive pH Response and High Relaxivity

Bei Li et al.

ADVANCED MATERIALS (2017)

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Review Chemistry, Physical

Exfoliation of layered double hydroxide solids into functional nanosheets

Ning Mao et al.

APPLIED CLAY SCIENCE (2017)

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Review Chemistry, Physical

Hybrid nanocomposites of layered double hydroxides: an update of their biological applications and future prospects

N'guadi Blaise Allou et al.

COLLOID AND POLYMER SCIENCE (2017)

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Article Nanoscience & Nanotechnology

Sustained Release of Brimonidine from a New Composite Drug Delivery System for Treatment of Glaucoma

Jianguo Sun et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Review Nanoscience & Nanotechnology

What is the role of curvature on the properties of nanomaterials for biomedical applications?

Estefania Gonzalez Solveyra et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2016)

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Article Engineering, Biomedical

Multifunctional properties of organic-inorganic hybrid nanocomposites based on chitosan derivatives and layered double hydroxides for ocular drug delivery

Tingting Xu et al.

ACTA BIOMATERIALIA (2016)

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Review Dermatology

Wound healing - A literature review

Ana Cristina de Oliveira Gonzalez et al.

ANAIS BRASILEIROS DE DERMATOLOGIA (2016)

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Article Chemistry, Multidisciplinary

Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation

Dae-Hwan Park et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

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Article Chemistry, Physical

Carboxymethyl cellulose capsulated layered double hydroxides/drug nanohybrids for Cephalexin oral delivery

Soroush Barkhordari et al.

APPLIED CLAY SCIENCE (2016)

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Review Chemistry, Physical

Mechanochemical approaches to synthesize layered double hydroxides: a review

Jun Qu et al.

APPLIED CLAY SCIENCE (2016)

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Review Pharmacology & Pharmacy

Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications

Anisha A. D'souza et al.

EXPERT OPINION ON DRUG DELIVERY (2016)

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Article Polymer Science

Hydrolytic degradation of nanocomposites based on poly(l-lactic acid) and layered double hydroxides modified with a model drug

Andrea Oyarzabal et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2016)

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Review Agriculture, Multidisciplinary

Electrospun nanofibres in agriculture and the food industry: a review

Masumeh Noruzi

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2016)

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Article Multidisciplinary Sciences

Accessing the biocompatibility of layered double hydroxide by intramuscular implantation: histological and microcirculation evaluation

Vanessa Roberta Rodrigues Cunha et al.

SCIENTIFIC REPORTS (2016)

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Article Materials Science, Biomaterials

Effect of the protein corona on the colloidal stability and reactivity of LDH-based nanocarriers

Cecilia Vasti et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

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Article Chemistry, Multidisciplinary

Layered double hydroxide and sulindac coiled and scrolled nanoassemblies for storage and drug release

Michele A. Rocha et al.

RSC ADVANCES (2016)

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Article Chemistry, Multidisciplinary

Radioisotope Co-57 incorporated layered double hydroxide nanoparticles as a cancer imaging agent

Tae-Hyun Kim et al.

RSC ADVANCES (2016)

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Review Chemistry, Physical

Layered double hydroxide nanoparticles for biomedical applications: Current status and recent prospects

Yaswanth Kuthati et al.

APPLIED CLAY SCIENCE (2015)

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Article Engineering, Chemical

Controlled drug release from pharmaceutical nanocarriers

Jinhyun Hannah Lee et al.

CHEMICAL ENGINEERING SCIENCE (2015)

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Review Chemistry, Multidisciplinary

Clinical Translation of Nanomedicine

Yuanzeng Min et al.

CHEMICAL REVIEWS (2015)

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Review Chemistry, Multidisciplinary

Mechanisms of Drug Release in Nanotherapeutic Delivery Systems

Pamela T. Wong et al.

CHEMICAL REVIEWS (2015)

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Review Chemistry, Multidisciplinary

Nanoparticle colloidal stability in cell culture media and impact on cellular interactions

Thomas L. Moore et al.

CHEMICAL SOCIETY REVIEWS (2015)

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Article Pharmacology & Pharmacy

Thermoplastic polyurethanes for the manufacturing of highly dosed oral sustained release matrices via hot melt extrusion and injection molding

Bart Claeys et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

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Article Chemistry, Physical

Cross linking to enhance colloidal stability and redispersity of layered double hydroxide nanoparticles

Huali Zuo et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2015)

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Article Chemistry, Physical

Multi-laminated metal hydroxide nanocontainers for oral-specific delivery for bioavailability improvement and treatment of inflammatory paw edema in mice

Ranjith Kumar Kankala et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2015)

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Article Chemistry, Multidisciplinary

Controlled Drug Delivery: Historical perspective for the next generation

Yeon Hee Yun et al.

JOURNAL OF CONTROLLED RELEASE (2015)

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Article Chemistry, Multidisciplinary

Organic-inorganic hybrid nanocomposites based on chitosan derivatives and layered double hydroxides with intercalated phacolysin as ocular delivery system

Zhiguo Qin et al.

JOURNAL OF NANOPARTICLE RESEARCH (2015)

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Article Engineering, Chemical

Preparation and characterization of cetirizine intercalated layered double hydroxide and chitosan nanocomposites

Kamellia Nejati et al.

JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS (2015)

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Article Materials Science, Multidisciplinary

Synthesis and characterization of new membranes based on sulfonated polysulfone/Zn,Al-heptamolibdate LDH

A. M. Martos et al.

MATERIALS LETTERS (2015)

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Review Chemistry, Multidisciplinary

Pharmacokinetics, pharmacodynamics and toxicology of theranostic nanoparticles

Homan Kang et al.

NANOSCALE (2015)

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Article Multidisciplinary Sciences

Chelator-Free Labeling of Layered Double Hydroxide Nanoparticles for in Vivo PET Imaging

Sixiang Shi et al.

SCIENTIFIC REPORTS (2015)

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Review Engineering, Biomedical

Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment

Nuria Oliva et al.

ADVANCED HEALTHCARE MATERIALS (2015)

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Article Materials Science, Biomaterials

Pre-coating layered double hydroxide nanoparticles with albumin to improve colloidal stability and cellular uptake

Zi Gu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

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Article Materials Science, Biomaterials

Size-tunable LDH-protein hybrids toward the optimization of drug nanocarriers

R. Rojas et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

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Review Chemistry, Multidisciplinary

Nanomaterials for Theranostics: Recent Advances and Future Challenges

Eun-Kyung Lim et al.

CHEMICAL REVIEWS (2015)

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Review Nanoscience & Nanotechnology

Utility of models of the gastrointestinal tract for assessment of the digestion and absorption of engineered nanomaterials released from food matrices

David E. Lefebvre et al.

NANOTOXICOLOGY (2015)

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Article Materials Science, Composites

Bionanocomposites Based on Alginate and Chitosan/Layered Double Hydroxide With Ciprofloxacin Drug: Investigation of Structure and Controlled Release Properties

Zolfaghar Rezvani et al.

POLYMER COMPOSITES (2015)

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Article Chemistry, Multidisciplinary

Exfoliation and dispersion of LDH modified with N-tetrabromophthaloyl-glutamic in poly(vinyl alcohol): Morphological and thermal studies

Shadpour Mallakpour et al.

JOURNAL OF CHEMICAL SCIENCES (2015)

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Article Chemistry, Multidisciplinary

A Supermolecular Photosensitizer with Excellent Anticancer Performance in Photodynamic Therapy

Ruizheng Liang et al.

ADVANCED FUNCTIONAL MATERIALS (2014)

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Article Chemistry, Multidisciplinary

Novel Nanocomposite Hydrogels Consisting of Layered Double Hydroxide with Ultrahigh Tensibility and Hierarchical Porous Structure at Low Inorganic Content

Ziqiao Hu et al.

ADVANCED MATERIALS (2014)

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Review Chemistry, Physical

Intercalation of drugs in layered double hydroxides and their controlled release: A review

Vicente Rives et al.

APPLIED CLAY SCIENCE (2014)

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There is no such thing as a biocompatible material

David F. Williams

BIOMATERIALS (2014)

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PEGylated PAMAM dendrimer-doxorubicin conjugate-hybridized gold nanorod for combined photothermal-chemotherapy

Xiaojie Li et al.

BIOMATERIALS (2014)

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Article Biotechnology & Applied Microbiology

Kinome Profiling of Osteoblasts on Hydroxyapatite Opens New Avenues on Biomaterial Cell Signaling

Sara Gemini-Piperni et al.

BIOTECHNOLOGY AND BIOENGINEERING (2014)

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Preparation and properties of carboxymethyl cellulose/layered double hydroxide bionanocomposite films

Mehdi Yadollahi et al.

CARBOHYDRATE POLYMERS (2014)

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Inorganic nanomaterials for bioimaging, targeted drug delivery and therapeutics

Ruizheng Liang et al.

CHEMICAL COMMUNICATIONS (2014)

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Hot-melt extrusion - basic principles and pharmaceutical applications

Bo Lang et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2014)

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Bionanocomposites containing magnetic graphite as potential systems for drug delivery

Ligia N. M. Ribeiro et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)

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ZIP2 Protein, a Zinc Transporter, Is Associated with Keratinocyte Differentiation

Yu Inoue et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

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Theranostic nanoparticles for future personalized medicine

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JOURNAL OF CONTROLLED RELEASE (2014)

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Controlled drug delivery systems: Past forward and future back

Kinam Park

JOURNAL OF CONTROLLED RELEASE (2014)

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pH sensitive nanocomposite hydrogel beads based on carboxymethyl cellulose/layered double hydroxide as drug delivery systems

Soroush Barkhordari et al.

JOURNAL OF POLYMER RESEARCH (2014)

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Nanocomposite-Strengthened Dissolving Microneedles for Improved Transdermal Delivery to Human Skin

Li Yan et al.

ADVANCED HEALTHCARE MATERIALS (2014)

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The role of iron in the skin and cutaneous wound healing

Josephine A. Wright et al.

FRONTIERS IN PHARMACOLOGY (2014)

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Layered Double Hydroxide-Based Nanocarriers for Drug Delivery

Xue Bi et al.

Pharmaceutics (2014)

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Fabrication and sustained release properties of poly(ε-caprolactone) electrospun fibers loaded with layered double hydroxide nanoparticles intercalated with amoxicillin

Eduardo Valarezo et al.

APPLIED CLAY SCIENCE (2013)

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Drug-inorganic-polymer nanohybrid for transdermal delivery

Myung Hun Kim et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

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Preparation of pH-Sensitive Polymers/Layered Double Hydroxide Hybrid Beads for Controlled Release of Insulin

Mehrdad Mahkam et al.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2013)

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Layered double hydroxides as drug carriers and for controlled release of non-steroidal antiinflammatory drugs (NSAIDs): A review

Vicente Rives et al.

JOURNAL OF CONTROLLED RELEASE (2013)

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Layered double hydroxide induced advancement in joint prosthesis using bone cement: the effect of metal substitution

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JOURNAL OF MATERIALS CHEMISTRY B (2013)

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Cellular uptake and gene delivery using layered double hydroxide nanoparticles

Shuangde Li et al.

JOURNAL OF MATERIALS CHEMISTRY B (2013)

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Polymethylmethacrylate bone cements and additives: A review of the literature

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WORLD JOURNAL OF ORTHOPEDICS (2013)

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Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

S. M. Moghimi et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)

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Drug release from layered double hydroxides and from their polylactic acid (PLA) nanocomposites

María S. San Román et al.

APPLIED CLAY SCIENCE (2012)

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Structural, Spectroscopic (NMR, IR, and Raman), and DFT Investigation of the Self-Assembled Nanostructure of Pravastatin-LDH (Layered Double Hydroxides) Systems

Vanessa R. R. Cunha et al.

CHEMISTRY OF MATERIALS (2012)

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Synthesis of polymer-inorganic filler nanocomposites in supercritical CO2

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JOURNAL OF SUPERCRITICAL FLUIDS (2012)

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Nomenclature of the hydrotalcite supergroup: natural layered double hydroxides

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MINERALOGICAL MAGAZINE (2012)

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LDH Nanocontainers as Bio-Reservoirs and Drug Delivery Carriers

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RECENT PATENTS ON NANOTECHNOLOGY (2012)

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Progress in developing spray-drying methods for the production of controlled morphology particles: From the nanometer to submicrometer size ranges

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ADVANCED POWDER TECHNOLOGY (2011)

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Theranostics: Combining Imaging and Therapy

Sneha S. Kelkar et al.

BIOCONJUGATE CHEMISTRY (2011)

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Poly(ethylene glycol) haired layered double hydroxides as biocompatible nanovehicles: Morphology and dispersity study

Dongxiang Li et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2011)

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Drug release characteristics from nanoclay hybrids and their dispersions in organic polymers

Jin Uk Ha et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)

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Controlled freezing and freeze drying: a versatile route for porous and micro-/nano-structured materials

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JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2011)

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Bacterial cellulose-laponite clay nanocomposites

Gustavo F. Perotti et al.

POLYMER (2011)

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New nanocomposite hydrogels containing layered double hydroxide

Toshiyuki Hibino

APPLIED CLAY SCIENCE (2010)

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Signalling pathways involved in the activation of dendritic cells by layered double hydroxide nanoparticles

Ang Li et al.

BIOMATERIALS (2010)

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Electrospinning: A fascinating fiber fabrication technique

Nandana Bhardwaj et al.

BIOTECHNOLOGY ADVANCES (2010)

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Preparation and Swelling Properties of pH-Sensitive Sodium Alginate/Layered Double Hydroxides Hybrid Beads for Controlled Release of Diclofenac Sodium

Jun-Ping Zhang et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2010)

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Factors Affecting Wound Healing

S. Guo et al.

JOURNAL OF DENTAL RESEARCH (2010)

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Bionanocomposites based on alginate-zein/layered double hydroxide materials as drug delivery systems

A. C. S. Alcantara et al.

JOURNAL OF MATERIALS CHEMISTRY (2010)

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Twenty-first century challenges for biomaterials

Larry L. Hench et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2010)

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Nanopharmacy: Inorganic nanoscale devices as vectors and active compounds

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PHARMACOLOGICAL RESEARCH (2010)

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LAYERED DOUBLE HYDROXIDES: INORGANIC NANOPARTICLES FOR STORAGE AND RELEASE OF SPECIES OF BIOLOGICAL AND THERAPEUTIC INTEREST

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QUIMICA NOVA (2010)

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New Polymeric Composites Based on Poly(ε-caprolactone) and Layered Double Hydroxides Containing Antimicrobial Species

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ACS APPLIED MATERIALS & INTERFACES (2009)

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Investigation of alginate beads for gastro-intestinal functionality, Part 1: In vitro characterisation

Phillippa Rayment et al.

FOOD HYDROCOLLOIDS (2009)

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Nanocomposites coated with xyloglucan for drug delivery: In vitro studies

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INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)

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Polymer nanocomposites using zinc aluminum and magnesium aluminum oleate layered double hydroxides: Effects of the polymeric compatibilizer and of composition on the thermal and fire properties of PP/LDH nanocomposites

Charles Manzi-Nshuti et al.

POLYMER DEGRADATION AND STABILITY (2009)

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Layered particle-based polymer composites for coatings: Part I. Evaluation of layered double hydroxides

Anne-Lise Troutier-Thuilliez et al.

PROGRESS IN ORGANIC COATINGS (2009)

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Preparation of layered double hydroxide microspheres by spray drying

Yanchang Wang et al.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2008)

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Subcellular compartment targeting of layered double hydroxide nanoparticles

Zhi Ping Xu et al.

JOURNAL OF CONTROLLED RELEASE (2008)

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Hydrotalcite-like compounds: Versatile layered hosts of molecular anions with biological activity

Umberto Costantino et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2008)

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Preparation of dual crosslinked alginate-chitosan blend gel beads and in vitro controlled release in oral site-specific drug delivery system

Yongmei Xu et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

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Intercalation behavior of L-ascorbic acid into layered double hydroxides

Sumio Aisawa et al.

APPLIED CLAY SCIENCE (2007)

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Layered double hydroxides and human health: An overview

C. Del Hoyo

APPLIED CLAY SCIENCE (2007)

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Cellular uptake mechanism of an inorganic nanovehicle and its drug conjugates: Enhanced efficacy due to clathrin-mediated endocytosis

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BIOCONJUGATE CHEMISTRY (2006)

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Spectroscopic characterization of polyaniline formed in the presence of montmorillonite clay

Gustavo M. do Nascimento et al.

POLYMER (2006)

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Stable suspension of layered double hydroxide nanoparticles in aqueous solution

ZP Xu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

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Enteric-coated layered double hydroxides as a controlled release drug delivery system

BX Li et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2004)

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Layered double hydroxide as an efficient drug reservoir for folate derivatives

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BIOMATERIALS (2004)

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