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Inactivation of Vhl in Osteochondral Progenitor Cells Causes High Bone Mass Phenotype and Protects Against Age-Related Bone Loss in Adult Mice
Tujun Weng et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway
J-H. Chung et al.
JOURNAL OF PERIODONTAL RESEARCH (2014)
Laser-induced osteoblast proliferation is mediated by ROS production
Mario Migliario et al.
LASERS IN MEDICAL SCIENCE (2014)
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
Anjali P. Kusumbe et al.
NATURE (2014)
Endothelial Notch activity promotes angiogenesis and osteogenesis in bone
Saravana K. Ramasamy et al.
NATURE (2014)
Osteoblast-Secreted Factors Promote Proliferation and Osteogenic Differentiation of Bone Marrow Stromal Cells via VEGF/Heme-Oxygenase-1 Pathway
Lian-Fang Zhang et al.
PLOS ONE (2014)
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Prevents Steroid-Associated Osteonecrosis of the Femoral Head in Rabbits by Promoting Angiogenesis and Inhibiting Apoptosis
Lihong Fan et al.
PLOS ONE (2014)
Dimethyloxalylglycine Prevents Bone Loss in Ovariectomized C57BL/6J Mice through Enhanced Angiogenesis and Osteogenesis
Jia Peng et al.
PLOS ONE (2014)
Up-regulation of glycolytic metabolism is required for HIF1α-driven bone formation
Jenna N. Regan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potential
Hao Ding et al.
STEM CELLS AND DEVELOPMENT (2014)
Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells
Chengtie Wu et al.
ACTA BIOMATERIALIA (2013)
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) enhances osteoclast differentiation via the up-regulation of Notch1 protein stability
Yun-Hee Choi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Calvarial defect healing by recruitment of autogenous osteogenic stem cells using locally applied simvastatin
Cui Yueyi et al.
BIOMATERIALS (2013)
Localized deferoxamine injection augments vascularity and improves bony union in pathologic fracture healing after radiotherapy
Alexis Donneys et al.
BONE (2013)
Deferoxamine enhances neovascularization and accelerates wound healing in diabetic rats via the accumulation of hypoxia-inducible factor-1α
Zhanjiang Hou et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2013)
BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells
Ning Hu et al.
JOURNAL OF CELL SCIENCE (2013)
Src kinases mediate VEGFR2 transactivation by the osteostatin domain of PTHrP to modulate osteoblastic function
Adela Garcia-Martin et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
Advances in the Regulation of Osteoclasts and Osteoclast Functions
B. F. Boyce
JOURNAL OF DENTAL RESEARCH (2013)
Ocular neovascularization
Peter A. Campochiaro
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells
Girish Pattappa et al.
TISSUE ENGINEERING PART C-METHODS (2013)
Constitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state
In-Ho Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering
Chengtie Wu et al.
BIOMATERIALS (2012)
Blood vessel formation in the tissue-engineered bone with the constitutively active form of HIF-1α mediated BMSCs
Duohong Zou et al.
BIOMATERIALS (2012)
Mice with increased angiogenesis and osteogenesis due to conditional activation of HIF pathway in osteoblasts are protected from ovariectomy induced bone loss
Qiang Zhao et al.
BONE (2012)
Deferoxamine reverses radiation induced hypovascularity during bone regeneration and repair in the murine mandible
Aaron S. Farberg et al.
BONE (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing
Tomoaki Fukui et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study
Weibin Zhang et al.
JOURNAL OF ORTHOPAEDIC SCIENCE (2012)
Repairing critical-sized calvarial defects with BMSCs modified by a constitutively active form of hypoxia-inducible factor-1α and a phosphate cement scaffold
Duohong Zou et al.
BIOMATERIALS (2011)
In vitro study of enhanced osteogenesis induced by HIF-1α-transduced bone marrow stem cells
D. Zou et al.
CELL PROLIFERATION (2011)
Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth
Roselyne Castonguay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Hypoxia-inducible Factor-1α Protein Negatively Regulates Load-induced Bone Formation
Ryan C. Riddle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Evaluation of the osteoconductivity of α-tricalcium phosphate, β-tricalcium phosphate, and hydroxyapatite combined with or without simvastatin in rat calvarial defect
Hisham Rojbani et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2011)
Increasing Vascularity to Improve Healing of a Segmental Defect of the Rat Femur
Rena Stewart et al.
JOURNAL OF ORTHOPAEDIC TRAUMA (2011)
Hypoxia Inhibits Osteogenesis in Human Mesenchymal Stem Cells through Direct Regulation of RUNX2 by TWIST
Der-Chih Yang et al.
PLOS ONE (2011)
Repair of Critical-Sized Rat Calvarial Defects Using Genetically Engineered Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor-1α
Duohong Zou et al.
STEM CELLS (2011)
The Influence of Hypoxia and Fibrinogen Variants on the Expansion and Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells
Ester M. Weijers et al.
TISSUE ENGINEERING PART A (2011)
Hypoxia Induces Osteogenesis-Related Activities and Expression of Core Binding Factor α1 in Mesenchymal Stem Cells
Jiao Huang et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Hypoxia-inducible factors and the prevention of acute organ injury
Samuel N. Heyman et al.
CRITICAL CARE (2011)
Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload
Gillian C. Smith et al.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (2011)
Enhancing in vivo vascularized bone formation by cobalt chloride-treated bone marrow stromal cells in a tissue engineered periosteum model
Wei Fan et al.
BIOMATERIALS (2010)
Iron chelator deferoxamine alters iron-regulatory genes and proteins and suppresses osteoblast phenotype in fetal rat calvaria cells
Jonathan G. Messer et al.
BONE (2010)
Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1α
Damian C. Genetos et al.
CELL AND TISSUE RESEARCH (2010)
Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells
Antonina Lavrentieva et al.
CELL COMMUNICATION AND SIGNALING (2010)
Hypoxia-Inducible Factor-1 as Regulator of Angiogenesis in Rheumatoid Arthritis - Therapeutic Implications
J. Westra et al.
CURRENT MEDICINAL CHEMISTRY (2010)
The Regulation of Differentiation in Mesenchymal Stem Cells
Andrea Augello et al.
HUMAN GENE THERAPY (2010)
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice
Emma C. Walker et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis
Sara I. Cunha et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Synthesis and characterization of hypoxia-mimicking bioactive glasses for skeletal regeneration
M. M. Azevedo et al.
JOURNAL OF MATERIALS CHEMISTRY (2010)
Melatonin suppresses tumor angiogenesis by inhibiting HIF-1α stabilization under hypoxia
Shi-Young Park et al.
JOURNAL OF PINEAL RESEARCH (2010)
Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands
Xiaoxia Z. West et al.
NATURE (2010)
The Essential Toxin: Impact of Zinc on Human Health
Laura M. Plum et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2010)
Simvastatin locally applied from a biodegradable coating of osteosynthetic implants improves fracture healing comparable to BMP-2 application
S. Pauly et al.
BONE (2009)
Reduced Adipose Tissue Oxygenation in Human Obesity Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
Magdalena Pasarica et al.
DIABETES (2009)
DEFEROXAMINE MIMICS THE PATTERN OF HYPOXIA-RELATED INJURY AT THE MICROVASCULATURE
Sonja Bartolome et al.
SHOCK (2009)
TWIST Family of Basic Helix-Loop-Helix Transcription Factors Mediate Human Mesenchymal Stem Cell Growth and Commitment
Sandra Isenmann et al.
STEM CELLS (2009)
Cardiotrophin-1 Is an Osteoclast-Derived Stimulus of Bone Formation Required for Normal Bone Remodeling
Emma C. Walker et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
The hypoxia-inducible factor a pathway couples angiogenesis to osteogenesis during skeletal development
Ying Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Synergistic effects of CoCl2 and ROCK inhibition on mesenchymal stem cell differentiation into neuron-like cells
Emilie Pacary et al.
JOURNAL OF CELL SCIENCE (2006)
EGF-ERBB signalling: towards the systems level
Ami Citri et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Cbfa1 couples chondrocytes maturation and endochondral ossification in rat mandibular condylar cartilage
ABM Rabie et al.
ARCHIVES OF ORAL BIOLOGY (2004)
Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development
D Pfander et al.
DEVELOPMENT (2004)
Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)
HW Cheng et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2003)
Hypoxia is a major stimulator of osteoclast formation and bone resorption
TR Arnett et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage
M Hill et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Cobalt inhibits the interaction between hypoxia-inducible factor-α and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-α
Y Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
KS Hewitson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation
K Nakashima et al.
CELL (2002)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
HIF-1 and mechanisms of hypoxia sensing
GL Semenza
CURRENT OPINION IN CELL BIOLOGY (2001)
Effects of deferoxamine, a chelator of free iron, on Na+, K+-ATPase activity of cortical brain cell membrane during early reperfusion after hypoxia-ischemia in newborn lambs
F Groenendaal et al.
PEDIATRIC RESEARCH (2000)
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
M Ohh et al.
NATURE CELL BIOLOGY (2000)
Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: Synergy with dexamethasone
CD Richards et al.
CYTOKINE (2000)