☆ 4.6 Review

Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health

CELLS (2023)

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Interleukin 10 and interleukin 10 receptor in paediatric inflammatory bowel disease: from bench to bedside lesson

Paulina Krawiec et al.

Summary: Inflammatory bowel disease (IBD) presents differently in children compared to adults, with early-onset IBD associated with single genetic mutations and older children and adolescents having polygenic interactions. Identifying defects in the Il-10 pathway can lead to early recognition and management of IBD in children.

JOURNAL OF INFLAMMATION-LONDON (2021)

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Review Biotechnology & Applied Microbiology

Pediococcus pentosaceus, a future additive or probiotic candidate

Shiman Jiang et al.

Summary: Pediococcus pentosaceus, a promising strain of lactic acid bacteria, has advantages such as improving taste and nutrition of food, as well as antimicrobial abilities. Further study of P. pentosaceus strains is needed to clarify their benefits and drawbacks for future applications.

MICROBIAL CELL FACTORIES (2021)

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Review Immunology

Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body

Fernanda Cristofori et al.

Summary: The digestive tract is a key site for microbial colonization, playing a vital role in maintaining host immune homeostasis. The interaction between gut microbiota/probiotics and the immune system can modulate inflammatory responses and prevent unnecessary activation of the immune system, offering potential therapeutic benefits.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Nutrition & Dietetics

Targeting Probiotics in Rheumatoid Arthritis

Simona Gabriela Bungau et al.

Summary: Rheumatoid arthritis (RA) is a progressive inflammatory disorder that can be caused by genetic, environmental, and gut microbiota imbalance factors. Probiotics, such as Lactobacillus, may help alleviate RA symptoms and could be a potential therapeutic option for treatment.

NUTRIENTS (2021)

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Article Microbiology

Eosinophils mediate SIgA production triggered by TLR2 and TLR4 to control Ascaris suum infection in mice

Denise Silva Nogueira et al.

Summary: The study found that TLR2 and TLR4 signaling induces eosinophils and promotes SIgA production during parasite infection, controlling parasite burden. Additionally, eosinophils participate in tissue remodeling after lung injury caused by larval migration.

PLOS PATHOGENS (2021)

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Review Microbiology

Current and Future Perspectives on the Role of Probiotics, Prebiotics, and Synbiotics in Controlling Pathogenic Cronobacter Spp. in Infants

Alfred Ke et al.

Summary: Cronobacter species, particularly C. sakazakii, pose a risk of severe illness in infants, with probiotics, prebiotics, and synbiotics showing potential efficacy in reducing invasive Cronobacter infections during early infancy.

FRONTIERS IN MICROBIOLOGY (2021)

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Review Microbiology

Pediococcus pentosaceus: Screening and Application as Probiotics in Food Processing

Yining Qi et al.

Summary: Pediococcus pentosaceus is a type of lactic acid bacteria with various probiotic effects such as antioxidant, cholesterol-lowering, and immune effects. It is important to screen P. pentosaceus with abundant functions from diverse sources for applications in probiotic-fermentation products.

FRONTIERS IN MICROBIOLOGY (2021)

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Review Microbiology

Lactiplantibacillus plantarum-Nomad and Ideal Probiotic

Mario Fidanza et al.

Summary: Probiotics are increasingly recognized for positively modulating human health, with ideal probiotics possessing numerous attributes. Lactiplantibacillus plantarum demonstrates ecological and metabolic flexibility, enabling it to thrive in various environments. This review highlights the genetic and functional characteristics of Lp as an ideal probiotic, and summarizes current knowledge on its potential applications as a prophylactic or therapeutic intervention.

FRONTIERS IN MICROBIOLOGY (2021)

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Article Microbiology

Significantly Low Levels of IgG Antibodies Against Oncogenic Merkel Cell Polyomavirus in Sera From Females Affected by Spontaneous Abortion

Chiara Mazziotta et al.

Summary: This study investigated the impact of MCPyV infection on females affected by spontaneous abortion (SA), showing a significantly reduced IgG antibody response to MCPyV in females with SA.

FRONTIERS IN MICROBIOLOGY (2021)

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Review Chemistry, Multidisciplinary

Nutritional and Health Potential of Probiotics: A Review

Muhammad Modassar Ali Nawaz Ranjha et al.

Summary: This passage explains the various benefits of probiotics, including promoting the health of gut microbiota, preventing a range of diseases, improving oral, nutritional, and intestinal health, and providing a robust defense mechanism.

APPLIED SCIENCES-BASEL (2021)

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Article Microbiology

Alterations in Gut Microbiome Composition and Function in Irritable Bowel Syndrome and Increased Probiotic Abundance with Daily Supplementation

Joann Phan et al.

Summary: Irritable bowel syndrome (IBS) is characterized by abdominal discomfort and irregular bowel movements, with the gut microbiome posited to play a significant role. This study analyzed stool samples from individuals with IBS and without IBS and found differences in microbial features, with synbiotic supplementation showing potential to impact these features. Further research is needed to determine the relationship between microbiome changes and improvement in IBS symptoms.

MSYSTEMS (2021)

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Review Immunology

Human gut-associated lymphoid tissues (GALT); diversity, structure, and function

Urs M. Morbe et al.

Summary: Human GALT, including Peyer's patches, appendix, and ILF, plays a key role in antigen sampling and adaptive immune responses in the intestinal wall. Current understanding of human GALT is primarily based on studies in mice, and its relevance to human health remains unclear. Further research is needed to explore the structure, composition, and potential regulatory functions of human GALT in intestinal immune responses.

MUCOSAL IMMUNOLOGY (2021)

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Article Multidisciplinary Sciences

Serum cytokine patterns are modulated in infants fed formula with probiotics or milk fat globule membranes: A randomized controlled trial

Xiaonan Li et al.

Summary: The study found that adding F19 to formula milk resulted in higher IL-2 concentrations and lower IFN-γ concentrations compared to standard formula, while the MFGM group had slightly lower IL-2 and IL-17A concentrations. There were no significant differences in vaccine responses among the formula groups, and the cytokine concentrations in the MFGM group were closer to those of breastfed infants.

PLOS ONE (2021)

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Review Immunology

Modulatory Effects of Probiotics During Pathogenic Infections With Emphasis on Immune Regulation

Abdul Raheem et al.

Summary: The widespread use of antibiotics can lead to a range of adverse effects, prompting the search for probiotics as alternatives. Probiotics play an important role in regulating host immune responses, with a focus on their application in infectious disease treatments garnering significant research interest.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Biotechnology & Applied Microbiology

Probiotics Interactions and the Modulation of Major Signalling Pathways in Host Model Organism Caenorhabditis elegans

Ramatchandirane Mahesh et al.

Summary: The gut microbiome plays a crucial role in maintaining health by influencing digestion, nutrient absorption, and immune system regulation. Caenorhabditis elegans is a well-suited model organism for probiotic research due to its feeding behavior on bacteria, allowing for faster investigations. The study highlights the importance of understanding probiotics regulation mechanisms in conserved signaling pathways and explores the future contributions of C. elegans in synthetic biology and probiotics engineering.

INDIAN JOURNAL OF MICROBIOLOGY (2021)

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Review Biotechnology & Applied Microbiology

The efficacy of probiotics in experimental autoimmune encephalomyelitis (an animal model for MS): a systematic review and meta-analysis

S. Valizadeh et al.

Summary: This systematic review and meta-analysis revealed that probiotics had significant effects on the incidence of EAE, weight gain, and clinical symptoms, with varying effects on disease duration based on probiotic strains. Probiotics were associated with a significant reduction in the risk of mortality only in female animals and showed promising effects in the prevention and management of EAE.

LETTERS IN APPLIED MICROBIOLOGY (2021)

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Article Microbiology

Probiotics Modulate Mouse Gut Microbiota and Influence Intestinal Immune and Serotonergic Gene Expression in a Site-Specific Fashion

Valentina Taverniti et al.

Summary: This study compared the effects of three different probiotic bacterial strains on three distinct murine intestinal sites, showing that probiotics can modulate the intestinal microbiota and affect host gene expression in a strain-specific manner. The study provides a rationale for investigating the effects of probiotics on the serotonergic system.

FRONTIERS IN MICROBIOLOGY (2021)

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Article Microbiology

A probiotic has differential effects on allergic airway inflammation in A/J and C57BL/6 mice and is correlated with the gut microbiome

Mateus B. Casaro et al.

Summary: The study found that probiotics can affect the diversity of gut microbiota in mice, and the abundance of different bacterial genera is also influenced by probiotics. Probiotics have a certain regulatory effect on airway inflammation, with acetate-producing probiotics having a positive impact on allergic inflammation.

MICROBIOME (2021)

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Review Immunology

Probiotics as Adjuvants in Vaccine Strategy: Is There More Room for Improvement?

Diego Giampietro Peroni et al.

Summary: Probiotics as vaccine adjuvants show promise in animal models and human studies, but their use in clinical applications remains controversial, especially in specific settings like late pregnancy. Further research is needed to fully understand their potential benefits and limitations.

VACCINES (2021)

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Article Microbiology

Evaluation of Probiotic Properties of Pediococcus acidilactici M76 Producing Functional Exopolysaccharides and Its Lactic Acid Fermentation of Black Raspberry Extract

Young-Ran Song et al.

Summary: PA-M76 demonstrated strong probiotic properties with high tolerance in GIT environments, broad antimicrobial activity, and effective immune response elicitation. Lactic acid fermentation of BRE by PA-M76 resulted in increased antioxidant activity, while not significantly affecting total anthocyanin and flavonoid content.

MICROORGANISMS (2021)

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Article Agriculture, Dairy & Animal Science

Impact of Escherichia coli probiotic strains ED1a and Nissle 1917 on the excretion and gut carriage of extended-spectrum beta-lactamase-producing E. coli in pigs

Gwenaelle Mourand et al.

Summary: The study evaluated the impact of administrating two Escherichia coli probiotic strains on the gut carriage or shedding of extended-spectrum beta-lactamase-producing E. coli in pigs, finding that the probiotics did not reduce the shedding of the challenge strain.

VETERINARY AND ANIMAL SCIENCE (2021)

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Article Biochemistry & Molecular Biology

Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1β pathway

Xina Dou et al.

Summary: L. casei ATCC 393 and its metabolites effectively alleviate DSS-induced UC in C57BL/6 mice by inhibiting immune cell infiltration, reducing pro-inflammatory factor production, increasing anti-inflammatory factor expression, and improving gut microbiota dysbiosis.

FOOD & FUNCTION (2021)

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Review Medicine, Research & Experimental

Novel Insights into the Role of Probiotics in Respiratory Infections, Allergies, Cancer, and Neurological Abnormalities

Igori Balta et al.

Summary: Probiotics have gained public attention in recent years, showcasing their immunomodulatory capabilities, anti-viral properties, anti-allergic effects, anticancer potential, and ability to improve neurological status. They offer therapeutic options for various diseases by regulating the immune system and microbiota.

DISEASES (2021)

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Review Gastroenterology & Hepatology

Probiotic and commensal gut microbial therapies in multiple sclerosis and its animal models: a comprehensive review

Lorrie L. Blais et al.

Summary: The need for alternative treatments for multiple sclerosis has led to extensive research on microbial therapies targeting the microbiota-gut-brain axis. This comprehensive review evaluates probiotic and commensal gut microbial therapies for MS based on clinical and preclinical evidence, ranking promising therapies and identifying areas needing further research for cheaper, safer, and more durable treatments.

GUT MICROBES (2021)

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Article Agriculture, Dairy & Animal Science

Optimizing the composition of the medium for the viable cells of Bifidobacterium animalis subsp. lactis JNU306 using response surface methodology

Thi Duyen Dang et al.

Summary: This research optimized the medium composition for Bifidobacterium animalis subsp lactis strain JNU306 using response surface methodology (RSM), resulting in a cost-effective solution for maximizing biomass production.

JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY (2021)

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Review Agriculture, Dairy & Animal Science

The impact of probiotics on gut health via alternation of immune status of monogastric animals

Sujuan Ding et al.

Summary: The development of the intestinal immune system is influenced by various factors, and probiotics play a positive role in regulating intestinal immunity. Probiotics participate in regulating host health in multiple ways and have a certain regulatory effect on intestinal diseases.

ANIMAL NUTRITION (2021)

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Review Biochemistry & Molecular Biology

Biological characteristics of IL-6 and related intestinal diseases

Yuexin Guo et al.

Summary: This article summarizes the functions of IL-6 in maintaining intestinal homeostasis, explores its relation with the nervous system, and highlights its potential role in Parkinson's disease. It also points out the dual-sided influence of IL-6 on intestinal tumors and inflammation, and how they are achieved through different processes.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2021)

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Review Biochemistry & Molecular Biology

Chemical Metabolism of Xenobiotics by Gut Microbiota

Radislav Nakov et al.

CURRENT DRUG METABOLISM (2020)

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Review Infectious Diseases

Probiotics to manage inflammation in HIV infection

Dag Henrik Reikvam et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2020)

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Article Agriculture, Dairy & Animal Science

Microbiome and pathogen interaction with the immune system

Michael H. Kogut et al.

POULTRY SCIENCE (2020)

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Review Cell Biology

Interaction between microbiota and immunity in health and disease

Danping Zheng et al.

CELL RESEARCH (2020)

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Review Hematology

Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review

Taylor Halsey et al.

SEMINARS IN HEMATOLOGY (2020)

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Review Nutrition & Dietetics

The Effect of Probiotics on the Production of Short-Chain Fatty Acids by Human Intestinal Microbiome

Paulina Markowiak-Kopec et al.

NUTRIENTS (2020)

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Article Microbiology

Probiotic Mixture of Lactobacillus plantarum Strains Improves Lipid Metabolism and Gut Microbiota Structure in High Fat Diet-Fed Mice

Huizhen Li et al.

FRONTIERS IN MICROBIOLOGY (2020)

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Review Immunology

Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract

Bolun Zhou et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Microbiology

High Human Papillomavirus DNA loads in Inflammatory Middle Ear Diseases

Nicola Malagutti et al.

PATHOGENS (2020)

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Review Allergy

Probiotics function and modulation of the immune system in allergic diseases

M. Eslami et al.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA (2020)

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Review Gastroenterology & Hepatology

AGA Technical Review on the Role of Probiotics in the Management of Gastrointestinal Disorders

Geoffrey A. Preidis et al.

GASTROENTEROLOGY (2020)

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Editorial Material Gastroenterology & Hepatology

AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders

Grace L. Su et al.

GASTROENTEROLOGY (2020)

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Review Immunology

Cell-Mediated Immune Responses to COVID-19 Infection

Amelie Guihot et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Review Medicine, Research & Experimental

Gut microbiota-derived short-chain fatty acids and hypertension: Mechanism and treatment

Fan Yang et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

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Article Multidisciplinary Sciences

Effects of probiotics on salivary cytokines and immunoglobulines: a systematic review and meta-analysis on clinical trials

Soraiya Ebrahimpour-Koujan et al.

SCIENTIFIC REPORTS (2020)

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Letter Dermatology

Tissue cytokine/chemokine profile in vulvar lichen sclerosus: An observational study on keratinocyte and fibroblast cultures

Monica Corazza et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2020)

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Review Medicine, General & Internal

Probiotics: Versatile Bioactive Components in Promoting Human Health

Javad Sharifi-Rad et al.

MEDICINA-LITHUANIA (2020)

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Review Immunology

Immune System Modulations by Products of the Gut Microbiota

Thierry Chenard et al.

VACCINES (2020)

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Article Multidisciplinary Sciences

Probiotic Lactobacillus fermentum strain JDFM216 improves cognitive behavior and modulates immune response with gut microbiota

Mi Ri Park et al.

SCIENTIFIC REPORTS (2020)

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Review Immunology

Microbial metabolites and immune regulation: New targets for major depressive disorder

Andrea Merchak et al.

BRAIN, BEHAVIOR, & IMMUNITY - HEALTH (2020)

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Review Multidisciplinary Sciences

Global analysis of clinical trials with probiotics

Theresia M. G. Dronkers et al.

HELIYON (2020)

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Article Ophthalmology

IRT5 Probiotics Changes Immune Modulatory Protein Expression in the Extraorbital Lacrimal Glands of an Autoimmune Dry Eye Mouse Model

Se Hyun Choi et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2020)

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Review Biochemistry & Molecular Biology

Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-Review

Emanuel Vamanu et al.

BIOMEDICINES (2020)

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Review Food Science & Technology

The effects of probiotics in lactose intolerance: A systematic review

Sophia J. Oak et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2019)

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Editorial Material Biochemistry & Molecular Biology

Could Probiotics Be Used to Mitigate Neuroinflammation?

Matthew G. Frank et al.

ACS CHEMICAL NEUROSCIENCE (2019)

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Article Immunology

Effects and immune responses of probiotic treatment in ruminants

Sarah Raabis et al.

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2019)

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Article Microbiology

Probiotic Properties of Enterococcus Isolated From Artisanal Dairy Products

Yousef Nami et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Review Microbiology

Probiotic Bacteria: A Promising Tool in Cancer Prevention and Therapy

Agata Gorska et al.

CURRENT MICROBIOLOGY (2019)

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Review Immunology

Microbes, metabolites, and the gut-lung axis

Anh Thu Dang et al.

MUCOSAL IMMUNOLOGY (2019)

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Article Microbiology

Probiotic Potential and Safety Evaluation of Enterococcus faecalis OB14 and OB15, Isolated From Traditional Tunisian Testouri Cheese and Rigouta, Using Physiological and Genomic Analysis

Olfa Baccouri et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Article Oncology

Classical Hodgkin lymphoma cells may promote an IL-17-enriched microenvironment

Isacco Ferrarini et al.

LEUKEMIA & LYMPHOMA (2019)

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Article Biotechnology & Applied Microbiology

Probiotics isolated from yaks improves the growth performance, antioxidant activity, and cytokines related to immunity and inflammation in mice

Aoyun Li et al.

MICROBIAL CELL FACTORIES (2019)

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Review Microbiology

Role of the Microbiota in the Modulation of Vaccine Immune Responses

Annalisa Ciabattini et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Review Immunology

Commensal Bacteria: An Emerging Player in Defense Against Respiratory Pathogens

Rabia Khan et al.

FRONTIERS IN IMMUNOLOGY (2019)

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Article Immunology

Probiotics Lactobacillus reuteri Abrogates Immune Checkpoint Blockade-Associated Colitis by Inhibiting Group 3 Innate Lymphoid Cells

Tingting Wang et al.

FRONTIERS IN IMMUNOLOGY (2019)

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Article Pediatrics

Lactobacillus reuteri DSM 17938 Probiotics May Increase CC-Chemokine Receptor 7 Expression in Infants Treated With for Colic

Francesco Savino et al.

FRONTIERS IN PEDIATRICS (2019)

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Article Gastroenterology & Hepatology

Lactobacillus reuteri DSM 17938 feeding of healthy newborn mice regulates immune responses while modulating gut microbiota and boosting beneficial metabolites

Yuying Liu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2019)

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Article Nutrition & Dietetics

Mechanisms of Action of Probiotics

Julio Plaza-Diaz et al.

ADVANCES IN NUTRITION (2019)

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Review Gastroenterology & Hepatology

Efficacy of Lactobacillus rhamnosus GG in treatment of acute pediatric diarrhea: A systematic review with meta-analysis

Ya-Ting Li et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2019)

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Article Biotechnology & Applied Microbiology

Development of omics-based protocols for the microbiological characterization of multi-strain formulations marketed as probiotics: the case of VSL#3

Diego Mora et al.

MICROBIAL BIOTECHNOLOGY (2019)

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Article Biotechnology & Applied Microbiology

Novel Probiotic Mechanisms of the Oral Bacterium Streptococcus sp. A12 as Explored with Functional Genomics

K. Lee et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2019)

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Editorial Material Oncology

Death and the Miser: microbiota regulate the outcome of checkpoint inhibition immunotherapy

Ger T. Rijkers et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2019)

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Review Biochemistry & Molecular Biology

Cytokines in Inflammatory Disease

Shinwan Kany et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Cell Biology

BID and the α-bisabolol-triggered cell death program: converging on mitochondria and lysosomes

Antonella Rigo et al.

CELL DEATH & DISEASE (2019)

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Review Biochemistry & Molecular Biology

The inflammatory function of human IgA

Ivo S. Hansen et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

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Review Cell Biology

Probiotics importance and their immunomodulatory properties

Bahman Yousefi et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

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Article Microbiology

Elucidating the Immune-Related Mechanisms by Which Probiotic Strain Lactobacillus casei BL23 Displays Anti-tumoral Properties

Elsa Jacouton et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Article Food Science & Technology

Screening of Phosphate-accumulating Probiotics for Potential Use in Chronic Kidney Disorder

Ajeeta Anand et al.

FOOD SCIENCE AND TECHNOLOGY RESEARCH (2019)

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Review Microbiology

The Production and Delivery of Probiotics: A Review of a Practical Approach

Kurt Fenster et al.

MICROORGANISMS (2019)

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Review Biotechnology & Applied Microbiology

Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health

Andrea Monteagudo-Mera et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

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Review Endocrinology & Metabolism

Beneficial Effects of Probiotic Consumption on the Immune System

Carolina Maldonado Galdeano et al.

ANNALS OF NUTRITION AND METABOLISM (2019)

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Article Biotechnology & Applied Microbiology

Probiotics and the Gut Immune System: Indirect Regulation

Giorgio La Fata et al.

PROBIOTICS AND ANTIMICROBIAL PROTEINS (2018)

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Article Critical Care Medicine

Evaluation of Effect of Probiotics on Cytokine Levels in Critically Ill Children With Severe Sepsis: A Double-Blind, Placebo-Controlled Trial

Suresh K. Angurana et al.

CRITICAL CARE MEDICINE (2018)

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Review Neurosciences

The Microbiota-Gut-Brain Axis in Neuropsychiatric Disorders: Patho-physiological Mechanisms and Novel Treatments

Yong-Ku Kim et al.

CURRENT NEUROPHARMACOLOGY (2018)

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Review Immunology

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

Kumar Vijay

INTERNATIONAL IMMUNOPHARMACOLOGY (2018)

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Article Agriculture, Dairy & Animal Science

Enhanced phagocytosis of Aggregatibacter actinomycetemcomitans cells by macrophages activated by a probiotic Lactobacillus strain

N. Jaffar et al.

JOURNAL OF DAIRY SCIENCE (2018)

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Review Food Science & Technology

Benefaction of probiotics for human health: A review

Rout George Kerry et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2018)

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Article Nutrition & Dietetics

Anti-inflammatory effect of multistrain probiotic formulation (L. rhamnosus, B. lactis, and B. longum)

Marzia Sichetti et al.

NUTRITION (2018)

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Article Multidisciplinary Sciences

The molecular mechanism for activating IgA production by Pediococcus acidilactici K15 and the clinical impact in a randomized trial

Tadaomi Kawashima et al.

SCIENTIFIC REPORTS (2018)

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Article Immunology

The Potential for Topical Probiotic Treatment of Chronic Rhinosinusitis, a Personal Perspective

Anders U. Cervin

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)

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Article Biotechnology & Applied Microbiology

Cross-Feeding among Probiotic Bacterial Strains on Prebiotic Inulin Involves the Extracellular exo-Inulinase of Lactobacillus paracasei Strain W20

Markus C. L. Boger et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2018)

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Article Pharmacology & Pharmacy

Pre- and probiotic overview

Cesare Cremonl et al.

CURRENT OPINION IN PHARMACOLOGY (2018)

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Review Microbiology

The Genus Enterococcus: Between Probiotic Potential and Safety Concerns-An Update

Hasna Hanchi et al.

FRONTIERS IN MICROBIOLOGY (2018)

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Article Infectious Diseases

Probiotics Streptococcus salivarius 24SMB and Streptococcus oralis 89a interfere with biofilm formation of pathogens of the upper respiratory tract

Alessandro Bidossi et al.

BMC INFECTIOUS DISEASES (2018)

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Review Biotechnology & Applied Microbiology

Immunomodulatory Effects of Probiotics on Cytokine Profiles

Md. Abul Kalam Azad et al.

BIOMED RESEARCH INTERNATIONAL (2018)

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Article Biotechnology & Applied Microbiology

Nisin-induced expression of recombinant T cell epitopes of major Japanese cedar pollen allergens in Lactococcus lactis

Vinh Van Hoang et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2018)

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Review Genetics & Heredity

Interaction between gut microbiota and toll-like receptor: from immunity to metabolism

Jensen H. C. Yiu et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2017)

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Review Food Science & Technology

Probiotics, gut microbiota, and their influence on host health and disease

Borja Sanchez et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2017)

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Review Immunology

The respiratory tract microbiome and lung inflammation: a two-way street

G. B. Huffnagle et al.

MUCOSAL IMMUNOLOGY (2017)

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Article Biotechnology & Applied Microbiology

Effect of Potential Probiotic Lactococcus lactis Subsp lactis on Growth Performance, Intestinal Microbiota, Digestive Enzyme Activities, and Disease Resistance of Litopenaeus vannamei

Milad Adel et al.

PROBIOTICS AND ANTIMICROBIAL PROTEINS (2017)

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Article Gastroenterology & Hepatology

Commercial Probiotic Products: A Call for Improved Quality Control. A Position Paper by the ESPGHAN Working Group for Probiotics and Prebiotics

Sanja Kolacek et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2017)

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Article Oncology

Effects of probiotics on Toll-like receptor expression in ulcerative colitis rats induced by 2,4,6-trinitro-benzene sulfonic acid

Ping Yao et al.

MOLECULAR MEDICINE REPORTS (2017)

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Review Food Science & Technology

Is there a relationship between intestinal microbiota, dietary compounds, and obesity?

Joanna Kaluzna-Czaplinska et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2017)

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Review Nutrition & Dietetics

Microbiota and Probiotics in Health and HIV Infection

Chiara D'Angelo et al.

NUTRIENTS (2017)

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Review Nutrition & Dietetics

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health

Paulina Markowiak et al.

NUTRIENTS (2017)

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Article Immunology

2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea

Andi L. Shane et al.

CLINICAL INFECTIOUS DISEASES (2017)

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Review Cell Biology

Understanding the Holobiont: How Microbial Metabolites Affect Human Health and Shape the Immune System

Thomas Siegmund Postler et al.

CELL METABOLISM (2017)

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Review Biochemistry & Molecular Biology

Introduction to the human gut microbiota

Elizabeth Thursby et al.

BIOCHEMICAL JOURNAL (2017)

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Review Immunology

Role of intestinal microbiota and metabolites on gut homeostasis and human diseases

Lan Lin et al.

BMC IMMUNOLOGY (2017)

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Review Oncology

Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy

Vita Golubovskaya et al.

CANCERS (2016)

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Review Microbiology

INSIGHTS FROM 100 YEARS OF RESEARCH WITH PROBIOTIC E. COLI

Trudy M. Wassenaar

EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY (2016)

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Article Nutrition & Dietetics

Probiotic fermented milk consumption modulates the allergic process induced by ovoalbumin in mice

Eva M. M. Velez et al.

BRITISH JOURNAL OF NUTRITION (2015)

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Review Immunology

Regulatory categories of probiotics across the globe: A review representing existing and recommended categorization

M. Arora et al.

INDIAN JOURNAL OF MEDICAL MICROBIOLOGY (2015)

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Review Food Science & Technology

Microencapsulation of bacteria: A review of different technologies and their impact on the probiotic effects

Maria Jose Martin et al.

INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2015)

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Review Food Science & Technology

Probiotics, prebiotics and synbiotics- a review

Kavita R. Pandey et al.

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2015)

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Article Neurosciences

Probiotics Improve Inflammation-Associated Sickness Behavior by Altering Communication between the Peripheral Immune System and the Brain

Charlotte D'Mello et al.

JOURNAL OF NEUROSCIENCE (2015)

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Article Virology

The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

David S. Donaldson et al.

JOURNAL OF VIROLOGY (2015)

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Article Biochemistry & Molecular Biology

The toll-like receptor family protein RP105/MD1 complex is involved in the immunoregulatory effect of exopolysaccharides from Lactobacillus plantarum N14

Yo Murofushi et al.

MOLECULAR IMMUNOLOGY (2015)

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Article Nutrition & Dietetics

Lactobacillus casei CRL 431 administration decreases inflammatory cytokines in a diet-induced obese mouse model

Ivanna Novotny Nunez et al.

NUTRITION (2015)

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Article Physiology

NOD-Like Receptors: Guardians of Intestinal Mucosal Barriers

Anne-Kathrin Claes et al.

PHYSIOLOGY (2015)

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Article Gastroenterology & Hepatology

Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis

Tina Didari et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

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Review Food Science & Technology

Probiotics in valorization of innate immunity across various animal models

Seema Patel et al.

JOURNAL OF FUNCTIONAL FOODS (2015)

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Review Pediatrics

The Use of Probiotics in Pediatric Gastroenterology: A Review of the Literature and Recommendations by Latin-American Experts

Sylvia Cruchet et al.

PEDIATRIC DRUGS (2015)

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Article Microbiology

The effect of probiotics on serum levels of cytokine and endotoxin in peritoneal dialysis patients: a randomised, double-blind, placebo-controlled trial

I-K. Wang et al.

BENEFICIAL MICROBES (2015)

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Review Biotechnology & Applied Microbiology

Genomic Overview and Biological Functions of Exopolysaccharide Biosynthesis in Bifidobacterium spp.

Claudio Hidalgo-Cantabrana et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2014)

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Article Nutrition & Dietetics

Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study

Caroline E. Childs et al.

BRITISH JOURNAL OF NUTRITION (2014)

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Review Biochemistry & Molecular Biology

Role of the Microbiota in Immunity and Inflammation

Yasmine Belkaid et al.

CELL (2014)

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Review Food Science & Technology

Immune System Stimulation by Probiotic Microorganisms

Rabia Ashraf et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2014)

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Article Immunology

TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal Influenza Vaccination

Jason Z. Oh et al.

IMMUNITY (2014)

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Article Immunology

The administration of milk fermented by the probiotic Lactobacillus casei CRL 431 exerts an immunomodulatory effect against a breast tumour in a mouse model

Felix Aragon et al.

IMMUNOBIOLOGY (2014)

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Review Immunology

Intestinal IgA production and its role in host-microbe interaction

Cindy Gutzeit et al.

IMMUNOLOGICAL REVIEWS (2014)

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Article Gastroenterology & Hepatology

Use of Probiotics for Management of Acute Gastroenteritis: A Position Paper by the ESPGHAN Working Group for Probiotics and Prebiotics

Hania Szajewska et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2014)

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Article Gastroenterology & Hepatology

European Society for Pediatric Gastroenterology, Hepatology, and Nutrition/European Society for Pediatric Infectious Diseases Evidence-Based Guidelines for the Management of Acute Gastroenteritis in Children in Europe: Update 2014

Alfredo Guarino et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2014)

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Article Food Science & Technology

Altered human gut dendritic cell properties in ulcerative colitis are reversed by Lactobacillus plantarum extracellular encrypted peptide STp

Hafid O. Al-Hassi et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2014)

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Article Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

Colin Hill et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)

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Article Multidisciplinary Sciences

Lactobacillus gasseri SBT2055 Induces TGF-β Expression in Dendritic Cells and Activates TLR2 Signal to Produce IgA in the Small Intestine

Fumihiko Sakai et al.

PLOS ONE (2014)

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Article Biochemistry & Molecular Biology

GROWTH MEDIUM OPTIMIZATION FOR BIOMASS PRODUCTION OF A PROBIOTIC BACTERIUM, LACTOBACILLUS RHAMNOSUS ATCC 7469

C. P. Chang et al.

JOURNAL OF FOOD BIOCHEMISTRY (2013)

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Article Multidisciplinary Sciences

Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions

Francesca Turroni et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Article Gastroenterology & Hepatology

Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut

David Groeger et al.

GUT MICROBES (2013)

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Article Biotechnology & Applied Microbiology

Characterization of the SpaCBA Pilus Fibers in the Probiotic Lactobacillus rhamnosus GG

Justus Reunanen et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2012)

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Article Biotechnology & Applied Microbiology

Interaction of Bifidobacterium bifidum LMG13195 with HT29 Cells Influences Regulatory-T-Cell-Associated Chemokine Receptor Expression

Patricia Lopez et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2012)

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Article Microbiology

Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines

Marie-Anne von Schillde et al.

CELL HOST & MICROBE (2012)

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Review Immunology

CD4(+)T Cells: Differentiation and Functions

Rishi Vishal Luckheeram et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)

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Review Food Science & Technology

Microencapsulation of Probiotic Cells for Food Applications

Thomas Heidebach et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2012)

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Article Gastroenterology & Hepatology

Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells

Patrycja Konieczna et al.

GUT (2012)

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Editorial Material Gastroenterology & Hepatology

FAO/WHO Guidelines on Probiotics 10 Years Later FOREWORD

Lorenzo Morelli et al.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2012)

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Article Multidisciplinary Sciences

Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection

Saranna Fanning et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

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Review Gastroenterology & Hepatology

The intestinal microbiota, gastrointestinal environment and colorectal cancer: a putative role for probiotics in prevention of colorectal cancer?

M. Andrea Azcarate-Peril et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)

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Article Gastroenterology & Hepatology

Probiotics and immune health

Fang Yan et al.

CURRENT OPINION IN GASTROENTEROLOGY (2011)

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Review Microbiology

Microbiota restoration: natural and supplemented recovery of human microbial communities

Gregor Reid et al.

NATURE REVIEWS MICROBIOLOGY (2011)

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Article Gastroenterology & Hepatology

Intestinal microbiota in inflammatory bowel disease: Friend of foe?

Francesca Fava et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

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Article Biotechnology & Applied Microbiology

Characterization of Immunostimulatory CpG-Rich Sequences from Different Bifidobacterium Species

Odile Menard et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2010)

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Review Biochemical Research Methods

Application of probiotics in food products-challenges and new approaches

I. Jankovic et al.

CURRENT OPINION IN BIOTECHNOLOGY (2010)

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Review Immunology

Probiotics: multifarious oral vaccine against infectious traumas

Sarika Amdekar et al.

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2010)

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Article Immunology

Immune response of non-pathogenic Gram(+) and Gram(-) bacteria in inductive sites of the intestinal mucosa Study of the pathway of signaling involved

C. A. Dogi et al.

IMMUNOBIOLOGY (2010)

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Article Cell Biology

Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response

Megan Livingston et al.

IMMUNOLOGY AND CELL BIOLOGY (2010)

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Article Immunology

Regionalization of pIgR expression in the mucosa of mouse small intestine

Aldo A. Resendiz-Albor et al.

IMMUNOLOGY LETTERS (2010)

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Article Allergy

Oral Treatment with Probiotics Reduces Allergic Symptoms in Ovalbumin-Sensitized Mice: A Bacterial Strain Comparative Study

S. Hougee et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2010)

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Article Biotechnology & Applied Microbiology

Validation of the dorsal air pouch model to predict and examine immunostimulatory responses in the gut

A. Kourelis et al.

JOURNAL OF APPLIED MICROBIOLOGY (2010)

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Article Multidisciplinary Sciences

Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders

Ho-Keun Kwon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Article Gastroenterology & Hepatology

Yogurt Containing Probiotic Lactobacillus rhamnosus GR-1 and L. reuteri RC-14 Helps Resolve Moderate Diarrhea and Increases CD4 Count in HIV/AIDS Patients

Kingsley C. Anukam et al.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2009)

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Article Agriculture, Dairy & Animal Science

Mechanisms involved in the immunostimulation by probiotic fermented milk

Carolina Maldonado Galdeano et al.

JOURNAL OF DAIRY RESEARCH (2009)

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Article Gastroenterology & Hepatology

Therapeutic effects of four strains of probiotics on experimental colitis in mice

Lin-Lin Chen et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2009)

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Article Allergy

Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-γ and breast milk transforming growth factor-β and immunoglobin A detection

S. L. Prescott et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2008)

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Article Gastroenterology & Hepatology

Probiotics for children with diarrhea - An update

Stefano Guandalini

JOURNAL OF CLINICAL GASTROENTEROLOGY (2008)

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Article Food Science & Technology

Effect of cold storage on culture viability and some rheological properties of fermented milk prepared with yogurt and probiotic bacteria

Maria Regina Damin et al.

JOURNAL OF TEXTURE STUDIES (2008)

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Article Multidisciplinary Sciences

S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

Sergey R. Konstantinov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

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Article Nutrition & Dietetics

Lactobacillus acidophilus 74-2 and Bifidobacterium animalis subsp lactis DGCC 420 modulate unspecific cellular immune response in healthy adults

A. Klein et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2008)

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Article Allergy

Probiotic-induced suppression of allergic sensitization and airway inflammation is associated with an increase of T regulatory-dependent mechanisms in a murine model of asthma

W. Feleszko et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2007)

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Article Gastroenterology & Hepatology

The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells

C. Caballero-Franco et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)

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Article Pediatrics

Intestinal colonization, microbiota, and probiotics

Seppo Salminen et al.

JOURNAL OF PEDIATRICS (2006)

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Article Biochemistry & Molecular Biology

A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine proteases

Dmitri Ivanov et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

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Article Biotechnology & Applied Microbiology

pH-, lactic acid-, and non-lactic acid-dependent activities of probiotic lactobacilli against Salmonella enterica serovar typhimurium

D Fayol-Messaoudi et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)

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Article Multidisciplinary Sciences

Enhanced anti inflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids

C Grangette et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

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Article Immunology

Probiotic Lactobacillus spp. diminish Helicobacter hepaticus-induced inflammatory bowel disease in interleukin-10-deficient mice

JA Peña et al.

INFECTION AND IMMUNITY (2005)

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Article Biotechnology & Applied Microbiology

Role of viability of probiotic strains in their persistence in the gut and in mucosal immune stimulation

CM Galdeano et al.

JOURNAL OF APPLIED MICROBIOLOGY (2004)

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Article Gastroenterology & Hepatology

Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance

J McCarthy et al.

GUT (2003)

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Article Gastroenterology & Hepatology

Increased mucosal tumour necrosis factor α production in Crohn's disease can be downregulated ex vivo by probiotic bacteria

N Borruel et al.

GUT (2002)

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Article Nutrition & Dietetics

Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019):: optimization and definition of cellular immune responses

BL Chiang et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2000)

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Article Gastroenterology & Hepatology

Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures

D Haller et al.

GUT (2000)

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Article Nutrition & Dietetics

Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019)

K Arunachalam et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2000)

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