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Cartilage Repair in a Rat Model of Osteoarthritis Through Intraarticular Transplantation of Muscle-Derived Stem Cells Expressing Bone Morphogenetic Protein 4 and Soluble Flt-1
Tomoyuki Matsumoto et al.
ARTHRITIS AND RHEUMATISM (2009)
Migratory Chondrogenic Progenitor Cells from Repair Tissue during the Later Stages of Human Osteoarthritis
Sebastian Koelling et al.
CELL STEM CELL (2009)
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
Bryan T. MacDonald et al.
DEVELOPMENTAL CELL (2009)
Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes
Timoklia Orfanidou et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Periodic Knee Injections of BMP-7 Delay Cartilage Degeneration Induced by Excessive Running in Rats
Ichiro Sekiya et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2009)
Comparative chondrogenesis of human cell sources in 3D scaffolds
R. Seda Tigli et al.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2009)
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
Shuibing Chen et al.
NATURE CHEMICAL BIOLOGY (2009)
Unravelling the relationship between age, nociception and joint destruction in naturally occurring osteoarthritis of Dunkin Hartley guinea pigs
Jason J. McDougall et al.
PAIN (2009)
Chondrogenic Differentiation of Adipose-Derived Adult Stem Cells by a Porous Scaffold Derived from Native Articular Cartilage Extracellular Matrix
Nai-Chen Cheng et al.
TISSUE ENGINEERING PART A (2009)
Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials - The cross trial safety analysis
Scott D. Solomon et al.
CIRCULATION (2008)
Mitogen-activated protein kinases as therapeutic targets in osteoarthritis
Richard F. Loeser et al.
CURRENT OPINION IN RHEUMATOLOGY (2008)
Smad7 inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways
Takao Iwai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Wnt/β-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes:: its possible role in joint degeneration
Takahito Yuasa et al.
LABORATORY INVESTIGATION (2008)
Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis
S. M. Botter et al.
OSTEOARTHRITIS AND CARTILAGE (2008)
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
W. Zhang et al.
OSTEOARTHRITIS AND CARTILAGE (2008)
Endochondral bone tissue engineering using embryonic stem cells
Jojanneke M. Jukes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
COX-2 Selective Inhibitors in the Treatment of Osteoarthritis
Loren Laine et al.
SEMINARS IN ARTHRITIS AND RHEUMATISM (2008)
Concise review:: Isolation and characterization of cells from human term placenta:: Outcome of the first international workshop on placenta derived stem cells
Ornella Parolini et al.
STEM CELLS (2008)
Molecular Trafficking Mechanisms of Multipotent Mesenchymal Stem Cells Derived from Human Bone Marrow and Placenta
Gary Brooke et al.
STEM CELLS AND DEVELOPMENT (2008)
Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease
Melina Daans et al.
ARTHRITIS RESEARCH & THERAPY (2008)
Engineered cartilage generated by nasal chondrocytes is responsive to physical forces resembling joint loading
C. Candrian et al.
ARTHRITIS AND RHEUMATISM (2008)
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Paul B. Yui et al.
NATURE CHEMICAL BIOLOGY (2008)
OP-1/BMP-7 in cartilage repair
Susan Chubinskaya et al.
INTERNATIONAL ORTHOPAEDICS (2007)
Chondrogenic differentiation of human bone marrow stem cells in transwell cultures: Generation of Scaffold-free cartilage
Alan D. Murdoch et al.
STEM CELLS (2007)
Concise review: Human umbilical cord stroma with regard to the source of fetus-derived stem cells
Alp Can et al.
STEM CELLS (2007)
The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse
S. S. Glasson et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Different response of articular chondrocyte subpopulations to surface motion
Z. Li et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow
Dolores Baksh et al.
STEM CELLS (2007)
Gradients in bone morphogenetic protein-related gene expression across the growth plate
Ola Nilsson et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Synovial stem cells are regionally specified according to local microenvironments after implantation for cartilage regeneration
Hideyuki Koga et al.
STEM CELLS (2007)
MMP and non-MMP-mediated release of aggrecan and its fragments from articular cartilage: a comparative study of three different aggrecan and glycosaminoglycan assays
E. U. Sumer et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
The role of TGFβs and Sox9 during limb chondrogenesis
Yasuhiko Kawakami et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification
Makoto Hirao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice
Karohina Pelttari et al.
ARTHRITIS AND RHEUMATISM (2006)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor
Yu-Feng Dong et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Hydrogels in biology and medicine: From molecular principles to bionanotechnology
Nicholas A. Peppas et al.
ADVANCED MATERIALS (2006)
Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation
S Provot et al.
DEVELOPMENT (2006)
Cartilage repair using bone morphogenetic protein 4 and muscle-derived stem cells
R Kuroda et al.
ARTHRITIS AND RHEUMATISM (2006)
Transforming growth factor-beta 2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E-2 production
EV Tchetina et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Osteoarthritis cartilage histopathology: grading and staging
KPH Pritzker et al.
OSTEOARTHRITIS AND CARTILAGE (2006)
TGF-β regulates the mechanical properties and composition of bone matrix
G Balooch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products
DL Cecil et al.
JOURNAL OF IMMUNOLOGY (2005)
Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes
C Sanchez et al.
OSTEOARTHRITIS AND CARTILAGE (2005)
Osteoarthritis development in novel experimental mouse models induced by knee joint instability
S Kamekura et al.
OSTEOARTHRITIS AND CARTILAGE (2005)
Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis
GY Wang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2005)
Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression
DW Burton et al.
OSTEOARTHRITIS AND CARTILAGE (2005)
Retaining zonal chondrocyte phenotype by means of novel growth environments
EM Darling et al.
TISSUE ENGINEERING (2005)
Effect of inhibition of matrix metalloproteinases on cartilage loss in vitro and in a guinea pig model of osteoarthritis
M Sabatini et al.
ARTHRITIS AND RHEUMATISM (2005)
Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method
CM Flahiff et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation
GY Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The surface of articular cartilage contains a progenitor cell population
GP Dowthwaite et al.
JOURNAL OF CELL SCIENCE (2004)
Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway
TF Li et al.
EXPERIMENTAL CELL RESEARCH (2004)
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression
AE Zuniga et al.
GENES & DEVELOPMENT (2004)
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
RB Vega et al.
CELL (2004)
A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage
N Nakayama et al.
DEVELOPMENT (2004)
Effects of Ca2+ sensing receptor activation in the growth plate
SF Wu et al.
FASEB JOURNAL (2004)
Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta
PS in't Anker et al.
STEM CELLS (2004)
Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood
K Bieback et al.
STEM CELLS (2004)
NF-κB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro
JQ Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels
WH Liu et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2003)
Partial characterization of cell-type X collagen interactions
SP Luckman et al.
BIOCHEMICAL JOURNAL (2003)
Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes
A Barbero et al.
ARTHRITIS AND RHEUMATISM (2003)
Localization of bone morphogenetic protein-2 in human osteoarthritic cartilage and osteophyte
T Nakase et al.
OSTEOARTHRITIS AND CARTILAGE (2003)
Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage
H Enomoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading
RL Mauck et al.
OSTEOARTHRITIS AND CARTILAGE (2003)
Inhibition of endogenous TGF-β during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair
A Scharstuhl et al.
JOURNAL OF IMMUNOLOGY (2002)
Human knee and ankle cartilage explants: catabolic differences
W Eger et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2002)
Mechanical and architectural bone adaptation in early stage experimental osteoarthritis
SK Boyd et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2002)
The canine 'groove' model, compared with the ACLT model of osteoarthritis
ACA Marijnissen et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
LA Neuhold et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants
AJ Fosang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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