4.6 Article

Dosimetric Benefit of Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy of Liver Metastases

Related references

Note: Only part of the references are listed.
Article Oncology

Online adaptive MR-guided stereotactic radiotherapy for unresectable malignancies in the upper abdomen using a 1.5T MR-linac

Lois A. Daamen et al.

Summary: This study evaluated the feasibility of MR-guided SBRT on a 1.5 T MR-linac for patients with unresectable upper abdominal malignancies. The results indicated that the treatment was effectively completed in the majority of cases and well-tolerated by the patients.

ACTA ONCOLOGICA (2022)

Article Oncology

MRI-Guided Online Adaptive Stereotactic Body Radiation Therapy of Liver and Pancreas Tumors on an MR-Linac System

Teo Stanescu et al.

Summary: This article describes a comprehensive workflow for MRI-guided online adaptive stereotactic body radiation therapy (SBRT) specific to upper gastrointestinal cancer patients with abdominal compression on a 1.5T MR-Linac system. The study shows that the workflow is feasible for these patients and significantly reduces treatment session time.

CANCERS (2022)

Article Oncology

MR-guided adaptive versus ITV-based stereotactic body radiotherapy for hepatic metastases (MAESTRO): a randomized controlled phase II trial

P. Hoegen et al.

Summary: The MAESTRO trial aims to evaluate the potential advantages of adaptive, gated MR-guided SBRT compared to conventional SBRT in the treatment of liver metastases, offering superior soft-tissue contrast for enhanced target identification and the benefit of daily real-time adaptive treatment.

RADIATION ONCOLOGY (2022)

Article Oncology

Dosimetric benefit of MR-guided online adaptive radiotherapy in different tumor entities: liver, lung, abdominal lymph nodes, pancreas and prostate

Lukas Nierer et al.

Summary: This study evaluated the dosimetric benefits of online adaptive MR-guided radiotherapy (oMRgRT) across different tumor entities and found significant improvements in target volume coverage and organ at risk (OAR) sparing. Different tumor subgroups showed varying degrees of improvement, with the liver, lung, and abdominal lymph nodes subgroups benefiting the most.

RADIATION ONCOLOGY (2022)

Article Oncology

Local Control After Stereotactic Body Radiation for Liver Tumors

Pelvis Nitin Ohri et al.

Summary: The study evaluated local control rates after SBRT for primary and metastatic liver tumors. Results showed high rates of durable local control for primary liver tumors with no clear dose-response relationship, while better outcomes were observed for liver metastases treated with higher BEDs.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

Article Oncology

Radiation Dose-Volume Effects for Liver SBRT

Moyed Miften et al.

Summary: SBRT is an effective, noninvasive treatment option for primary liver cancer and metastatic disease in the liver, although there is a tradeoff between tumor control and normal tissue complications. This study aimed to review the dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and develop normal tissue complication probability models.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

Article Oncology

Benefit of replanning in MR-guided online adaptive radiation therapy in the treatment of liver metastasis

Michael Mayinger et al.

Summary: Daily adaptive MR-guided replanning in SBRT for liver metastases improved target coverage and organs at risk sparing for metastases close to luminal OARs < 2 cm. Marginal improvements were observed for distant targets to critical OARs, indicating limited benefit from daily adaptive replanning for these patients.

RADIATION ONCOLOGY (2021)

Article Oncology

Feasibility and Early Clinical Experience of Online Adaptive MR-Guided Radiotherapy of Liver Tumors

Paul Rogowski et al.

Summary: This study retrospectively assessed the feasibility and early results of online adaptive MR-guided radiotherapy for liver tumors using a 0.35T hybrid MR-Linac. The treatment was successfully completed in all cases, with no local failure or ≥ grade two toxicity observed after a median follow-up of five months. Early results show promising outcomes for MR-linac based oMRgRT in the treatment of primary and secondary liver tumors.

CANCERS (2021)

Article Oncology

Magnetic Resonance-Guided Stereotactic Body Radiotherapy of Liver Tumors: Initial Clinical Experience and Patient-Reported Outcomes

Fabian Weykamp et al.

Summary: SBRT is an effective treatment option for non-resectable liver metastases or HCC, with MR-guided SBRT showing promise in improving treatment quality. This study analyzed the outcomes of MR-guided SBRT for liver tumors, showing high local control and overall survival rates with minimal toxicity. Prospective studies are needed to fully evaluate the potential of this technology.

FRONTIERS IN ONCOLOGY (2021)

Article Oncology

Toward Personalized Radiation Therapy of Liver Metastasis: Importance of Serial Blood Biomarkers

Ali Ajdari et al.

Summary: The study found that blood biomarkers, including gene mutation status, complete blood count, and inflammatory cytokine concentration, play an important role in predicting response to liver metastasis stereotactic body radiation therapy.

JCO CLINICAL CANCER INFORMATICS (2021)

Article Oncology

Stereotactic MR-guided online adaptive radiation therapy (SMART) for the treatment of liver metastases in oligometastatic patients: initial clinical experience

Gamze Ugurluer et al.

Summary: This retrospective study presented initial clinical experience on the implementation of stereotactic MR-guided online adaptive radiation therapy (SMART) for liver metastases in oligometastatic disease. The results showed promising outcomes with high response rates and overall survival in patients treated with SMART.

RADIATION ONCOLOGY JOURNAL (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

Intrafractional fiducial marker position variations in stereotactic liver radiotherapy during voluntary deep inspiration breath-hold

Line Bjerregaard Stick et al.

BRITISH JOURNAL OF RADIOLOGY (2020)

Review Oncology

Recent advanced in Surface Guided Radiation Therapy

P. Freislederer et al.

RADIATION ONCOLOGY (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Assessment of online adaptive MR-guided stereotactic body radiotherapy of liver cancers

Kyle R. Padgett et al.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2020)

Article Oncology

High versus low dose Stereotactic Body Radiation Therapy for hepatic metastases

Esther N. D. Kok et al.

CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY (2020)

Review Oncology

Technical design and concept of a 0.35 T MR-Linac

Sebastian Klueter

CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY (2019)

Article Oncology

MR-guided Gated Stereotactic Radiation Therapy Delivery for Lung, Adrenal, and Pancreatic Tumors: A Geometric Analysis

John R. van Sornsen de Koste et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)

Article Oncology

Direct dose correlation of MRI morphologic alterations of healthy liver tissue after robotic liver SBRT

Judit Boda-Heggemann et al.

STRAHLENTHERAPIE UND ONKOLOGIE (2018)

Article Oncology

Local Control Outcomes Using Stereotactic Body Radiation Therapy for Liver Metastases From Colorectal Cancer

Ji Hyeon Joo et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2017)

Review Oncology

Deep Inspiration Breath Hold-Based Radiation Therapy: A Clinical Review

Judit Boda-Heggemann et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2016)

Article Oncology

MRI morphologic alterations after liver SBRT

Judit Boda-Heggemann et al.

STRAHLENTHERAPIE UND ONKOLOGIE (2016)

Article Oncology

Long-term safety and efficacy of stereotactic body radiation therapy for hepatic oligometastases

Benjamin D. Goodman et al.

PRACTICAL RADIATION ONCOLOGY (2016)

Article Oncology

Impact of inadequate respiratory motion management in SBRT for oligometastatic colorectal cancer

Robbe Van den Begin et al.

RADIOTHERAPY AND ONCOLOGY (2014)

Article Oncology

Predictor of Severe Gastroduodenal Toxicity After Stereotactic Body Radiotherapy for Abdominopelvic Malignancies

Sun Hyun Bae et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2012)

Article Oncology

RADIATION DOSE-VOLUME EFFECTS IN THE STOMACH AND SMALL BOWEL

Brian D. Kavanagh et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)

Article Oncology

Adaptive Management of Liver Cancer Radiotherapy

Kristy K. Brock et al.

SEMINARS IN RADIATION ONCOLOGY (2010)