Oxidative Drugs and microRNA: New Opportunities for Cancer Prevention

Article Oncology

Efficacy of High-Ozonide Oil in Prevention of Cancer Relapses Mechanisms and Clinical Evidence

Alberto Izzotti et al.

Summary: Ozonized oils can effectively decrease the risk of cancer relapses by damaging cancer cells and triggering apoptosis. Administering ozonized oil orally can significantly decrease blood antioxidants in cancer patients, resulting in improved survival rate and decreased relapses.

CANCERS (2022)

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Article Health Care Sciences & Services

Relationship between the miRNA Profiles and Oncogene Mutations in Non-Smoker Lung Cancer. Relevance for Lung Cancer Personalized Screenings and Treatments

Alberto Izzotti et al.

Summary: The study analyzed the interplay between miRNA expression and oncogene mutation, finding that miRNA analysis was more informative for predicting patient survival compared to mutation analysis.

JOURNAL OF PERSONALIZED MEDICINE (2021)

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Article Health Care Sciences & Services

Prevention of Covid-19 Infection and Related Complications by Ozonized Oils

Alberto Izzotti et al.

Summary: A new chemoprophylactic/therapeutic strategy using HOO/HOOws was developed to effectively prevent and treat COVID-19 infection. In vitro and in vivo studies demonstrated the efficacy and safety of this treatment, showing promising results in preventing infection and accelerating recovery in COVID-19 patients.

JOURNAL OF PERSONALIZED MEDICINE (2021)

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Article Chemistry, Multidisciplinary

Pulmonary Aerosol Delivery of Let-7b microRNA Confers a Striking Inhibitory Effect on Lung Carcinogenesis through Targeting the Tumor Immune Microenvironment

Qi Zhang et al.

Summary: MicroRNAs, such as let-7b, show promise for lung cancer prevention and therapy, with the potential to inhibit tumor growth by modulating immune responses through downregulation of PD-L1 and PD-1 in the tumor microenvironment. Aerosolized let-7b treatment demonstrates significant antitumor effects without detectable side effects, suggesting it as a promising approach for lung cancer prevention.

ADVANCED SCIENCE (2021)

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Article Cell Biology