Related references
Note: Only part of the references are listed.Tumor-derived exosomes elicit cancer-associated fibroblasts shaping inflammatory tumor microenvironment in head and neck squamous cell carcinoma
Ikko Mito et al.
ORAL ONCOLOGY (2023)
Tumor-Derived Exosomes in Tumor-Induced Immune Suppression
Qiongyu Hao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Neoantigen quality predicts immunoediting in survivors of pancreatic cancer
Marta Luksza et al.
NATURE (2022)
Breast tumor microenvironment structures are associated with genomic features and clinical outcome
Esther Danenberg et al.
NATURE GENETICS (2022)
IL-3 signalling in the tumour microenvironment shapes the immune response via tumour endothelial cell-derived extracellular vesicles
Tatiana Lopatina et al.
PHARMACOLOGICAL RESEARCH (2022)
The therapeutic potential of stem cell-derived exosomes in the ulcerative colitis and colorectal cancer
Gang Guo et al.
STEM CELL RESEARCH & THERAPY (2022)
Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics
Abhimanyu Thakur et al.
BIOACTIVE MATERIALS (2022)
In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
Yuxin Guo et al.
NATURE COMMUNICATIONS (2022)
NK cells-directed therapies target circulating tumor cells and metastasis
Hassan Dianat-Moghadam et al.
CANCER LETTERS (2021)
Mesenchymal Stem Cell-Secreted Extracellular Vesicles Instruct Stepwise Dedifferentiation of Breast Cancer Cells into Dormancy at the Bone Marrow Perivascular Region
Oleta A. Sandiford et al.
CANCER RESEARCH (2021)
Interferons in cancer immunoediting: sculpting metastasis and immunotherapy response
Michelle von Locquenghien et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis
Yu-feng Chen et al.
MOLECULAR MEDICINE (2021)
Tumor-derived exosomal microRNA-106b-5p activates EMT-cancer cell and M2-subtype TAM interaction to facilitate CRC metastasis
Chaogang Yang et al.
MOLECULAR THERAPY (2021)
A long way to go: caspase inhibitors in clinical use
Shanel Dhani et al.
CELL DEATH & DISEASE (2021)
Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation
Karthik Dhatchinamoorthy et al.
FRONTIERS IN IMMUNOLOGY (2021)
Interferon regulatory factor 1(IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC)
Yihe Yan et al.
CANCER LETTERS (2021)
LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis
Minghe Zhou et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)
Bone marrow cells are differentiated into MDSCs by BCC-Ex through down-regulating the expression of CXCR4 and activating STAT3 signalling pathway
Quan-Wen Liu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL
Gerardo Ferrer et al.
LEUKEMIA (2021)
Glycolysis reprogramming in cancer-associated fibroblasts promotes the growth of oral cancer through the lncRNA H19/miR-675-5p/PFKFB3 signaling pathway
Jin Yang et al.
INTERNATIONAL JOURNAL OF ORAL SCIENCE (2021)
Potential Use of Exosomes as Diagnostic Biomarkers and in Targeted Drug Delivery: Progress in Clinical and Preclinical Applications
Md Nurul Huda et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy
Mengshi Jiang et al.
ACS NANO (2021)
Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells
Wei Qiu et al.
MOLECULAR THERAPY (2021)
Graphene-Induced Hyperthermia (GIHT) Combined With Radiotherapy Fosters Immunogenic Cell Death
Malgorzata J. Podolska et al.
FRONTIERS IN ONCOLOGY (2021)
Tumor-Derived Extracellular Vesicles Promote Activation of Carcinoma-Associated Fibroblasts and Facilitate Invasion and Metastasis of Ovarian Cancer by Carrying miR-630
Yulan Cui et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Systemic immunity in cancer
Kamir J. Hiam-Galvez et al.
NATURE REVIEWS CANCER (2021)
OSCC cell-secreted exosomal CMTM6 induced M2-like macrophages polarization via ERK1/2 signaling pathway
Xin Pang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2021)
ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts
Jin Sol Sung et al.
ONCOGENE (2020)
The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction
Benjamin T. Himes et al.
NEURO-ONCOLOGY (2020)
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
Floriane Pelon et al.
NATURE COMMUNICATIONS (2020)
Inhibiting extracellular vesicles formation and release: a review of EV inhibitors
Mariadelva Catalano et al.
JOURNAL OF EXTRACELLULAR VESICLES (2020)
miR-210 transferred by lung cancer cell-derived exosomes may act as proangiogenic factor in cancer-associated fibroblasts by modulating JAK2/STAT3 pathway
Junqiang Fan et al.
CLINICAL SCIENCE (2020)
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK-mediated endoplasmic reticulum stress
Tao Shen et al.
FASEB JOURNAL (2020)
Tumor-associated macrophages promote prostate cancer progression via exosome-mediated miR-95 transfer
Han Guan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Antitumor efficacy of interferon-γ-modified exosomal vaccine in prostate cancer
Xiaojun Shi et al.
PROSTATE (2020)
Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice
Bingfeng Zuo et al.
NATURE COMMUNICATIONS (2020)
LPS Induces Active HMGB1 Release From Hepatocytes Into Exosomes Through the Coordinated Activities of TLR4 and Caspase-11/GSDMD Signaling
Wenbo Li et al.
FRONTIERS IN IMMUNOLOGY (2020)
Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization
Alexandra Pritchard et al.
CELLS (2020)
Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer
Mengmeng Jiang et al.
ONCOGENE (2020)
Renal cancer-derived exosomes induce tumor immune tolerance by MDSCs-mediated antigen-specific immunosuppression
Yingying Gao et al.
CELL COMMUNICATION AND SIGNALING (2020)
Arginase-1+Exosomes from Reprogrammed Macrophages Promote Glioblastoma Progression
Juliana H. Azambuja et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Survivin in breast cancer-derived exosomes activates fibroblasts by up-regulating SOD1, whose feedback promotes cancer proliferation and metastasis
Kangdi Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer
Inga J. Beccard et al.
CANCERS (2020)
Mechanical strain induces phenotypic changes in breast cancer cells and promotes immunosuppression in the tumor microenvironment
Yong Wang et al.
LABORATORY INVESTIGATION (2020)
LncRNA-zinc finger protein 281 downregulates rho-associated coiled-coil containing protein kinase 1 by upregulating miR-144 in osteosarcoma
Yuxiong Shao et al.
ONCOLOGY LETTERS (2020)
Enhanced immunogenicity of leukemia-derived exosomes via transfection with lentiviral vectors encoding costimulatory molecules
Weiwei Hu et al.
CELLULAR ONCOLOGY (2020)
Mouse 4T1 Breast Cancer Cell-Derived Exosomes Induce Proinflammatory Cytokine Production in Macrophages via miR-183
Jian Guo et al.
JOURNAL OF IMMUNOLOGY (2020)
Evolutionary dynamics of neoantigens in growing tumors
Eszter Lakatos et al.
NATURE GENETICS (2020)
miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells
Xingju Zhang et al.
ONCOGENE (2020)
Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway
Yanyan Liu et al.
ONCOTARGETS AND THERAPY (2020)
Exosomal LGALS9 in the cerebrospinal fluid of glioblastoma patients suppressed dendritic cell antigen presentation and cytotoxic T-cell immunity
Ming Wang et al.
CELL DEATH & DISEASE (2020)
Immune suppressed tumor microenvironment by exosomes derived from gastric cancer cells via modulating immune functions
Juan Liu et al.
SCIENTIFIC REPORTS (2020)
PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
Xiaozhe Yin et al.
CELL REPORTS (2020)
Tumor-derived HMGB1 induces CD62Ldimneutrophil polarization and promotes lung metastasis in triple-negative breast cancer
Zhen Wang et al.
ONCOGENESIS (2020)
Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies
Kaijian Zhou et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer
Senlin Zhao et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Extracellular Vesicles-Mediated Transfer of miRNA Let-7b from PC3 Cells to Macrophages
Egidia Costanzi et al.
GENES (2020)
Melanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway
Chenmeiyi Wang et al.
CANCER MANAGEMENT AND RESEARCH (2020)
Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs
Li Qiao et al.
THERANOSTICS (2020)
Biology, Pathophysiological Role, and Clinical Implications of Exosomes: A Critical Appraisal
Arif Tasleem Jan et al.
CELLS (2019)
被撤回的出版物: Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma (Retracted article. See DEC, 2022)
Xiang-Guang Wu et al.
ANGIOGENESIS (2019)
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
Laura M. McLane et al.
Annual Review of Immunology (2019)
Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
Mauro Poggio et al.
CELL (2019)
SALL4-mediated upregulation of exosomal miR-146a-5p drives T-cell exhaustion by M2 tumor-associated macrophages in HCC
Chunlai Yin et al.
ONCOIMMUNOLOGY (2019)
Metabolic Control of Dendritic Cell Functions: Digesting Information
Stefanie K. Wculek et al.
FRONTIERS IN IMMUNOLOGY (2019)
Melanoma-derived exosomes induce reprogramming fibroblasts into cancer-associated fibroblasts via Gm26809 delivery
Tairan Hu et al.
CELL CYCLE (2019)
Identification of novel, immune-mediating extracellular vesicles in human lymphatic effluent draining primary cutaneous melanoma
Rachel L. G. Maus et al.
ONCOIMMUNOLOGY (2019)
Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
Tuying Yong et al.
NATURE COMMUNICATIONS (2019)
Simvastatin mediates inhibition of exosome synthesis, localization and secretion via multicomponent interventions
Ankur Kulshreshtha et al.
SCIENTIFIC REPORTS (2019)
Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples
Eleanor M. Scott et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression
Christopher Groth et al.
BRITISH JOURNAL OF CANCER (2019)
Glioma exosomes mediate the expansion and function of myeloid-derived suppressor cells through microRNA-29a/Hbp1 and microRNA-92a/Prkar1a pathways
Xiaofan Guo et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity
Mariantonia Logozzi et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2019)
Mechanisms of Metastatic Tumor Dormancy and Implications for Cancer Therapy
Christiana M. Neophytou et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Cancer immunoediting and resistance to T cell-based immunotherapy
Jake S. O'Donnell et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment
Takeshi Motohara et al.
ONCOGENE (2019)
Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral γδ T cell equilibrium via tumor-derived exosomes
Ling Li et al.
ONCOGENE (2019)
Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome
Alin Rai et al.
PROTEOMICS (2019)
Oral squamous cell carcinoma-derived exosomes promote M2 subtype macrophage polarization mediated by exosome-enclosed miR-29a-3p
Jinghua Cai et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)
Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine
Victoria D. Turubanova et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Cancer Immunosurveillance by T Cells
Samhita Rao et al.
BIOLOGY OF T CELLS - PT B (2019)
Necroptosis: a crucial pathogenic mediator of human disease
Mary E. Choi et al.
JCI INSIGHT (2019)
Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy
Hongyu Liu et al.
ONCOTARGET (2018)
Cancer-derived exosomes trigger endothelial to mesenchymal transition followed by the induction of cancer-associated fibroblasts
Ju Hun Yeon et al.
ACTA BIOMATERIALIA (2018)
Expression profiles and clinical value of plasma exosomal Tim-3 and Galectin-9 in non-small cell lung cancer
Jianwei Gao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth
Yi Yang et al.
CELL RESEARCH (2018)
Paracrine Wnt5a-beta-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
Fei Zhao et al.
IMMUNITY (2018)
Exosomes from heat-stressed tumour cells inhibit tumour growth by converting regulatory T cells to Th17 cells via IL-6
Danfeng Guo et al.
IMMUNOLOGY (2018)
Tumor exosomes block dendritic cells maturation to decrease the T cell immune response
Yongling Ning et al.
IMMUNOLOGY LETTERS (2018)
NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass
Lei Hou et al.
LABORATORY INVESTIGATION (2018)
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling
Cassandra Ringuette Goulet et al.
MOLECULAR CANCER RESEARCH (2018)
Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN
Ya-Ling Hsu et al.
MOLECULAR THERAPY (2018)
Chromosomal instability drives metastasis through a cytosolic DNA response
Samuel F. Bakhoum et al.
NATURE (2018)
Tumor-derived exosomes antagonize innate antiviral immunity
Liang Gao et al.
NATURE IMMUNOLOGY (2018)
Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins
Kalpana Deepa Priya Dorayappan et al.
ONCOGENE (2018)
Dendritic Cells Pulsed with Exosomes in Combination with PD-1 Antibody Increase the Efficacy of Sorafenib in Hepatocellular Carcinoma Model
Shengbin Shi et al.
TRANSLATIONAL ONCOLOGY (2018)
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
Tomer Cooks et al.
NATURE COMMUNICATIONS (2018)
CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs
Sukhbir Kaur et al.
SCIENTIFIC REPORTS (2018)
Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs
Julie M. Diamond et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Breast Cancer-Derived Exosomes Alter Macrophage Polarization via gp130/STAT3 Signaling
Sunyoung Ham et al.
FRONTIERS IN IMMUNOLOGY (2018)
LPS-Challenged Macrophages Release Microvesicles Coated With Histones
Rohini Ravindran Nair et al.
FRONTIERS IN IMMUNOLOGY (2018)
Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
Konrad Gabrusiewicz et al.
ONCOIMMUNOLOGY (2018)
Notch Signaling in the Tumor Microenvironment
Olivier Meurette et al.
CANCER CELL (2018)
Exosomes derived from hypoxic epithelial ovarian cancer cells deliver microRNAs to macrophages and elicit a tumor-promoted phenotype
Xin Chen et al.
CANCER LETTERS (2018)
Regulation of Macrophage Activation and Polarization by HCC-Derived Exosomal lncRNA TUC339
Xue Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Gang Chen et al.
NATURE (2018)
Post-Irradiated Tumor-Derived Exosomes Lead to Melanoma Tumor Growth Delay, Potentially Mediated by Death Associated Molecular Pattern (DAMPs) Proteins
K. K. Jella et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Thery et al.
JOURNAL OF EXTRACELLULAR VESICLES (2018)
Interferon regulatory factor 1 priming of tumour-derived exosomes enhances the antitumour immune response
Mu-qing Yang et al.
BRITISH JOURNAL OF CANCER (2018)
Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis
Sayantan Maji et al.
MOLECULAR CANCER RESEARCH (2017)
Regulated Polarization of Tumor-Associated Macrophages by miR-145 via Colorectal Cancer-Derived Extracellular Vesicles
Haruka Shinohara et al.
JOURNAL OF IMMUNOLOGY (2017)
Tumour-associated macrophages as treatment targets in oncology
Alberto Mantovani et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Breast cancer cell-derived exosomes and macrophage polarization are associated with lymph node metastasis
Yin Ji Piao et al.
Oncotarget (2017)
Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer
Yuki Takano et al.
ONCOTARGET (2017)
Human Melanoma-Derived Extracellular Vesicles Regulate Dendritic Cell Maturation
Rachel L. G. Maus et al.
FRONTIERS IN IMMUNOLOGY (2017)
Interlekukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Supressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer
Mengmeng Jiang et al.
FRONTIERS IN IMMUNOLOGY (2017)
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway
Yingying Shen et al.
ONCOIMMUNOLOGY (2017)
Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis
Elisabetta Vulpis et al.
ONCOIMMUNOLOGY (2017)
Tumor-derived exosomes induce CD8+ T cell suppressors
Brian T. Maybruck et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Systemic T Cells Immunosuppression of Glioma Stem Cell-Derived Exosomes Is Mediated by Monocytic Myeloid-Derived Suppressor Cells
Rossana Domenis et al.
PLOS ONE (2017)
Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells
Amrita Datta et al.
CANCER LETTERS (2017)
The immune response to secondary necrotic cells
Monika Sachet et al.
APOPTOSIS (2017)
Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes
Josephine Salimu et al.
JOURNAL OF EXTRACELLULAR VESICLES (2017)
Tumor-derived exosomes modulate PD-L1 expression in monocytes
Franziska Haderk et al.
SCIENCE IMMUNOLOGY (2017)
Glioma-derived extracellular vesicles selectively suppress immune responses
Justin E. Hellwinkel et al.
NEURO-ONCOLOGY (2016)
Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity
Alireza Labani-Motlagh et al.
TUMOR BIOLOGY (2016)
Immunosuppression of breast cancer cells mediated by transforming growth factor-beta in exosomes from cancer cells
Lei Rong et al.
ONCOLOGY LETTERS (2016)
The biology and function of exosomes in cancer
Raghu Kalluri
JOURNAL OF CLINICAL INVESTIGATION (2016)
Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma
Shu-Biao Ye et al.
JOURNAL OF PATHOLOGY (2016)
Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts
S. Baroni et al.
CELL DEATH & DISEASE (2016)
Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models
Alessia Bottos et al.
NATURE COMMUNICATIONS (2016)
Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression
Nami Yamada et al.
ONCOTARGET (2016)
Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages
Zhipeng Chen et al.
ONCOTARGET (2016)
Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages
Xiang Ying et al.
ONCOTARGET (2016)
Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling
Hua Shen et al.
PLOS GENETICS (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
Role of HLA-G and extracellular vesicles in renal cancer stem cell-induced inhibition of dendritic cell differentiation
Cristina Grange et al.
BMC CANCER (2015)
The paradoxical role of IL-10 in immunity and cancer
Mark H. Mannino et al.
CANCER LETTERS (2015)
Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock
Dahai Yang et al.
IMMUNITY (2015)
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Sonia A. Melo et al.
NATURE (2015)
Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio
Tianzhi Yang et al.
PHARMACEUTICAL RESEARCH (2015)
T-cell exhaustion in the tumor microenvironment
Y. Jiang et al.
CELL DEATH & DISEASE (2015)
Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p
Guoping Ding et al.
ONCOTARGET (2015)
Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice
Xiaoyu Gu et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells
Dhafer Mrizak et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Danger signalling during cancer cell death: origins, plasticity and regulation
A. D. Garg et al.
CELL DEATH AND DIFFERENTIATION (2014)
Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203
Min Zhou et al.
CELLULAR IMMUNOLOGY (2014)
Natural cytotoxicity receptors and their ligands
Philip H. Kruse et al.
IMMUNOLOGY AND CELL BIOLOGY (2014)
Local tumour hyperthermia as immunotherapy for metastatic cancer
Seiko Toraya-Brown et al.
INTERNATIONAL JOURNAL OF HYPERTHERMIA (2014)
Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8+ T Cells: Mechanism of Immune Evasion
Marie Lundholm et al.
PLOS ONE (2014)
Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells
Makiko Ono et al.
SCIENCE SIGNALING (2014)
Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma
Shu-biao Ye et al.
ONCOTARGET (2014)
Regulation of immune responses by extracellular vesicles
Paul D. Robbins et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Tumor Microenvironmental Conversion of Natural Killer Cells into Myeloid-Derived Suppressor Cells
Young-Jun Park et al.
CANCER RESEARCH (2013)
Microenvironmental regulation of tumor progression and metastasis
Daniela F. Quail et al.
NATURE MEDICINE (2013)
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
Sven Malchow et al.
SCIENCE (2013)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Anticancer Drugs Cause Release of Exosomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responses in Vitro
Li-Hong Lv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Expression of tumour-specific antigens underlies cancer immunoediting
Michel DuPage et al.
NATURE (2012)
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
Stephen B. Willingham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer
Anirban K. Mitra et al.
CANCER DISCOVERY (2012)
Primary sterile necrotic cells fail to cross-prime CD8+ T cells
Jaba Gamrekelashvili et al.
ONCOIMMUNOLOGY (2012)
The emergence of phox-ER stress induced immunogenic apoptosis
Abhishek D. Garg et al.
ONCOIMMUNOLOGY (2012)
Immunogenic cell death and DAMPs in cancer therapy
Dmitri V. Krysko et al.
NATURE REVIEWS CANCER (2012)
The blockade of immune checkpoints in cancer immunotherapy
Drew M. Pardoll
NATURE REVIEWS CANCER (2012)
Introduction of the CIITA gene into tumor cells produces exosomes with enhanced anti-tumor effects
Yeong Shin Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2011)
Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production
Aled Clayton et al.
JOURNAL OF IMMUNOLOGY (2011)
Chemokine-Containing Exosomes Are Released from Heat-Stressed Tumor Cells via Lipid Raft-Dependent Pathway and Act as Efficient Tumor Vaccine
Taoyong Chen et al.
JOURNAL OF IMMUNOLOGY (2011)
Tumor-Derived Exosomes Confer Antigen-Specific Immunosuppression in a Murine Delayed-Type Hypersensitivity Model
Chenjie Yang et al.
PLOS ONE (2011)
Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
Robert D. Schreiber et al.
SCIENCE (2011)
Increasing vaccine potency through exosome antigen targeting
Zachary C. Hartman et al.
VACCINE (2011)
Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes
Omodele Ashiru et al.
CANCER RESEARCH (2010)
Membrane-bound HSP70-engineered myeloma cell-derived exosomes stimulate more efficient CD8+ CTL- and NK-mediated antitumour immunity than exosomes released from heat-shocked tumour cells expressing cytoplasmic HSP70
Yufeng Xie et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells
Melissa G. Lechner et al.
JOURNAL OF IMMUNOLOGY (2010)
Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)
Marta Szajnik et al.
PLOS ONE (2010)
The polarization of immune cells in the tumour environment by TGFβ
Richard A. Flavell et al.
NATURE REVIEWS IMMUNOLOGY (2010)
MHC independent anti-tumor immune responses induced by Hsp70-enriched exosomes generate tumor regression in murine models
Jung-ah Cho et al.
CANCER LETTERS (2009)
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
Theocharis Panaretakis et al.
EMBO JOURNAL (2009)
Proteomic and immunologic analyses of brain tumor exosomes
Michael W. Graner et al.
FASEB JOURNAL (2009)
Induction of myeloid-derived suppressor cells by tumor exosomes
Xiaoyu Xiang et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Human Placenta Expresses and Secretes NKG2D Ligands via Exosomes that Down-Modulate the Cognate Receptor Expression: Evidence for Immunosuppressive Function
Malin Hedlund et al.
JOURNAL OF IMMUNOLOGY (2009)
Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes
Eva U. Wieckowski et al.
JOURNAL OF IMMUNOLOGY (2009)
Myeloid-derived suppressor cells as regulators of the immune system
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
Pingyan Cheng et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Human tumor-derived exosomes down-modulate NKG2D expression
Aled Clayton et al.
JOURNAL OF IMMUNOLOGY (2008)
Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
Shengming Dai et al.
MOLECULAR THERAPY (2008)
Adaptive immunity maintains occult cancer in an equilibrium state
Catherine M. Koebel et al.
NATURE (2007)
CD8+ dendritic cells use LFA-1 to capture MHC-peptide complexes from exosomes in vivo
Elodie Segura et al.
JOURNAL OF IMMUNOLOGY (2007)
Human tumor-derived exosomes selectively impair lymphocyte responses to interieukin-2
Aled Clayton et al.
CANCER RESEARCH (2007)
Exosomes with immune modulatory features are present in human breast milk
Charlotte Admyre et al.
JOURNAL OF IMMUNOLOGY (2007)
Redox-signaling transmitted in trans to neighboring cells by melanoma-derived TNF-containing exosomes
Anita Soderberg et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Tumor exosomes inhibit differentiation of bone marrow dendritic cells
Shaohua Yu et al.
JOURNAL OF IMMUNOLOGY (2007)
Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells
Weilin Chen et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
More efficient induction of HLA-A*0201-restricted and carcinoembryonic antigen (CEA)-specific CTL response by immunization with exosomes prepared from heat-stressed CEA-positive tumor cells
SM Dai et al.
CLINICAL CANCER RESEARCH (2005)
Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis
AJ Abusamra et al.
BLOOD CELLS MOLECULES AND DISEASES (2005)
A critical function for type I interferons in cancer immunoediting
GP Dunn et al.
NATURE IMMUNOLOGY (2005)
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells
R Gastpar et al.
CANCER RESEARCH (2005)
Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: Role in immune escape
V Huber et al.
GASTROENTEROLOGY (2005)
Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects
DD Taylor et al.
BRITISH JOURNAL OF CANCER (2005)
Cancer immunoediting: from immunosurveillance to tumor escape
GP Dunn et al.
NATURE IMMUNOLOGY (2002)
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
J Wolfers et al.
NATURE MEDICINE (2001)