Journal
JOURNAL OF CLINICAL MEDICINE
Volume 11, Issue 24, Pages -Publisher
MDPI
DOI: 10.3390/jcm11247535
Keywords
acne vulgaris; dermatology; treatment; compliance; persistence
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Acne vulgaris is a common skin condition that can have a major impact on patients' well-being and quality of life. Effective treatment remains a challenge, as many patients do not receive adequate treatment or do not comply with prescribed treatments. Understanding treatment options and factors affecting patients' compliance is crucial in choosing proper treatment.
Acne vulgaris is an extremely common skin condition, affecting a large population of adolescents, but at the same time, remaining a quite common issue in the group of adult patients. Its complex pathogenesis includes increased sebum secretion, impaired follicular keratinization, colonization of sebaceous glands with Cutibacterium acne bacteria, and the development of inflammation in pilosebaceous units. Although there are many methods of treatment available targeting the mechanisms mentioned above, a large percentage of patients remain undertreated or non-compliant with treatment. Ineffective treatment results in the formation of acne scars, which has a major impact on the well-being and quality of life of the patients. The aim of this publication was a review of available evidence on widely used and novel methods of topical and systemic treatment of acne, additionally including current literature-based analysis of factors affecting patients' compliance. The strengths and limitations of novel substances for treating acne were discussed. We conclude that an effective acne treatment remains a challenge. A better understanding of current treatment options and factors affecting patients' compliance could be a helpful tool in choosing a proper treatment option.
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