Journal
JOURNAL OF CLINICAL MEDICINE
Volume 11, Issue 23, Pages -Publisher
MDPI
DOI: 10.3390/jcm11237240
Keywords
hidradenitis suppurativa; acne inversa; dermatology; inflammation; treatment; adalimumab; targeted therapy; small molecules
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Funding
- Ruhr-Universitat Bochum
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Hidradenitis suppurativa is a chronic inflammatory skin disease that significantly impacts patients' quality of life and is associated with comorbidities. Treatment is complex, requiring personalized medical and surgical approaches. There is a need for new treatment options, and recent research has identified potential therapeutic targets.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients' quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring an individual approach with medical and surgical treatments available. However, especially in moderate-to-severe HS, there is an urgent need for new treatment approaches. In recent years, increased research has led to the identification of new potential therapeutic targets. This review aims to give a comprehensive and practical overview of current treatment options for HS. Furthermore, the clinically most advanced novel treatment approaches will be discussed.
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