A Review: Integrative Perspectives on the Features and Clinical Management of Psychotic Episodes in Pregnancy

Psychotic episodes represent one of the most complex manifestations of various mental illnesses, and these encompass a wide variety of clinical manifestations that together lead to high morbidity in the general population. Various mental illnesses are associated with psychotic episodes; in addition, although their incidence and prevalence rates have been widely described in the general population, their correct identification and treatment is a challenge for health professionals in relation to pregnancy. In pregnant women, psychotic episodes can be the consequence of the manifestation of a previous psychiatric illness or may begin during the pregnancy itself, placing not only the mother, but also the fetus at risk during the psychotic episode. In addition, we cannot forget that both pharmacological and nonpharmacological management are complex given the different teratogenic effects of various neuroleptic drugs or mood stabilizers; moreover, the recommendation is that patients should be followed together with different specialists to maintain close contact during puerperium given the high incidence of recurrence of psychotic episodes. In addition, we cannot forget that a large portion of these patients for whom the onset times of such episodes are during pregnancy have a greater probability of an unpredictable psychiatric illness that requires a postpartum follow up, in addition to the postpartum psychotic episodes, at some point in their lives. Therefore, the purpose of this review is to summarize the epidemiology of psychotic breaks during pregnancy related to the main mental illnesses that affect this population and to summarize the main pharmacological treatments available for their clinical management.

Automated summary

Psychotic episodes, which are complex manifestations of various mental illnesses, can have a significant impact on the general population. It is a challenge for healthcare professionals to identify and treat these episodes during pregnancy. Pregnant women can experience psychotic episodes as a result of pre-existing psychiatric illnesses or during pregnancy itself, putting both the mother and the fetus at risk. Managing these episodes is complicated due to different teratogenic effects of neuroleptic drugs and mood stabilizers, and close follow-up during the postpartum period is recommended. This review aims to summarize the epidemiology of psychotic breaks during pregnancy and the available pharmacological treatments for their clinical management.