Related references
Note: Only part of the references are listed.mRNA Vaccines in the COVID-19 Pandemic and Beyond
Michael J. Hogan et al.
ANNUAL REVIEW OF MEDICINE (2022)
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery
Jilian R. Melamed et al.
JOURNAL OF CONTROLLED RELEASE (2022)
CAR T cells produced in vivo to treat cardiac injury
Joel G. Rurik et al.
SCIENCE (2022)
Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA)
Ester Alvarez-Benedicto et al.
BIOMATERIALS SCIENCE (2022)
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs
Samuel T. LoPresti et al.
JOURNAL OF CONTROLLED RELEASE (2022)
Intracranial delivery of synthetic mRNA to suppress glioblastoma
Hao Peng et al.
MOLECULAR THERAPY-ONCOLYTICS (2022)
On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles
Sean A. Dilliard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Natural or Synthetic RNA Delivery: A Stoichiometric Comparison of Extracellular Vesicles and Synthetic Nanoparticles
Daniel E. Murphy et al.
NANO LETTERS (2021)
Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR-Cas gene editing
Shuai Liu et al.
NATURE MATERIALS (2021)
RNAi-Based Approaches for Pancreatic Cancer Therapy
Min Ju Kim et al.
PHARMACEUTICS (2021)
Specific Endothelial Cells Govern Nanoparticle Entry into Solid Tumors
Benjamin R. Kingston et al.
ACS NANO (2021)
Highly efficient CD4+T cell targeting and genetic recombination using engineered CD4+cell-homing mRNA-LNPs
Istvan Tombacz et al.
MOLECULAR THERAPY (2021)
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Namit Chaudhary et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
Julian D. Gillmore et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice
Alec W. Freyn et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2021)
Development of Extracellular Vesicle Therapeutics: Challenges, Considerations, and Opportunities
Bethany Claridge et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs
Melissa P. Lokugamage et al.
NATURE BIOMEDICAL ENGINEERING (2021)
Indications for hyperthermic intraperitoneal chemotherapy with cytoreductive surgery: a systematic review
Rebecca C. Auer et al.
EUROPEAN JOURNAL OF CANCER (2020)
Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
Margaret M. Billingsley et al.
NANO LETTERS (2020)
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier
Oscar A. Marcos-Contreras et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone
Ryan Reshke et al.
NATURE BIOMEDICAL ENGINEERING (2020)
Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs
John Kokkinos et al.
BIOMATERIALS (2020)
A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice
Alec W. Freyn et al.
MOLECULAR THERAPY (2020)
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Qiang Cheng et al.
NATURE NANOTECHNOLOGY (2020)
Optimization of 5 ' Untranslated Region of Modified mRNA for Use in Cardiac or Hepatic Ischemic Injury
Nishat Sultana et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2020)
A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo
Khalid A. Hajj et al.
NANO LETTERS (2020)
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults
Mark J. Mulligan et al.
NATURE (2020)
An mRNA Vaccine against SARS-CoV-2-Preliminary Report
L. A. Jackson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Advances in Exosome-Based Drug Delivery and Tumor Targeting: From Tissue Distribution to Intracellular Fate
Juntang Shao et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)
Optimization of cell culture conditions for exosome isolation using mini-size exclusion chromatography (mini-SEC)
Nils Ludwig et al.
EXPERIMENTAL CELL RESEARCH (2019)
mRNA Delivery for Therapeutic Anti-HER2 Antibody Expression In Vivo
Yulia Rybakova et al.
MOLECULAR THERAPY (2019)
A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
Markus Baiersdoerfer et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
Human 5′ UTR design and variant effect prediction from a massively parallel translation assay
Paul J. Sample et al.
NATURE BIOTECHNOLOGY (2019)
Rapid On-Demand Extracellular Vesicle Augmentation with Versatile Oligonucleotide Tethers
Saigopalakrishna S. Yerneni et al.
ACS NANO (2019)
Targeted Delivery of siRNA Lipoplexes to Cancer Cells Using Macrophage Transient Horizontal Gene Transfer
Elizabeth C. Wayne et al.
ADVANCED SCIENCE (2019)
Lymphatic Uptake of Liposomes after Intraperitoneal Administration Primarily Occurs via the Diaphragmatic Lymphatics and is Dependent on Liposome Surface Properties
Given Lee et al.
MOLECULAR PHARMACEUTICS (2019)
Branched-Tail Lipid Nanoparticles Potently Deliver mRNA In Vivo due to Enhanced Ionization at Endosomal pH
Khalid A. Hajj et al.
SMALL (2019)
Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery
Piotr S. Kowalski et al.
ADVANCED MATERIALS (2018)
Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes
Xiangwei Xiao et al.
CELL STEM CELL (2018)
Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis
Ema Robinson et al.
MOLECULAR THERAPY (2018)
Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
D. Adams et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct
Ruchi Jain et al.
NUCLEIC ACID THERAPEUTICS (2018)
Gene Therapy for Pancreatic Diseases: Current Status
Kenya Kamimura et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Pathogenesis of Type 1 Diabetes Mellitus and Rodent Experimental Models
I. G. Gvazava et al.
ACTA NATURAE (2018)
Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
Jason B. Miller et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination
Norbert Pardi et al.
NATURE (2017)
Systemic delivery of factor IX messenger RNA for protein replacement therapy
Suvasini Ramaswamy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics-An innate immune system standpoint
Yasmin Granot et al.
SEMINARS IN IMMUNOLOGY (2017)
Inflammatory responses and inflammation-associated diseases in organs
Linlin Chen et al.
Oncotarget (2017)
In vivo protein corona patterns of lipid nanoparticles
A. Amici et al.
RSC ADVANCES (2017)
Tools for translation: non-viral materials for therapeutic mRNA delivery
Khalid A. Hajj et al.
NATURE REVIEWS MATERIALS (2017)
A Combination RNAi-Chemotherapy Layer-by-Layer Nanoparticle for Systemic Targeting of KRAS/P53 with Cisplatin to Treat Non-Small Cell Lung Cancer
Li Gu et al.
CLINICAL CANCER RESEARCH (2017)
Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin
Michela Brazzoli et al.
JOURNAL OF VIROLOGY (2016)
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells
J. M. Bailey et al.
ONCOGENE (2016)
Extracellular vesicles for drug delivery
Pieter Vader et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
James C. Kaczmarek et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety
Satoshi Uchida et al.
BIOMATERIALS (2016)
Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
F. DeRosa et al.
GENE THERAPY (2016)
Adeno-associated virus (AAV) vectors in cancer gene therapy
Jorge L. Santiago-Ortiz et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression
Irene C. Turnbull et al.
MOLECULAR THERAPY (2016)
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
Joanna Kowal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors
Tomas Koblas et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2016)
Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
Norbert Pardi et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
Kevin J. Kauffman et al.
NANO LETTERS (2015)
Structural similarities and differences between the human and the mouse pancreas
Jurij Dolensek et al.
ISLETS (2015)
Prophylaxis of post-ERCP pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Updated June 2014
Jean-Marc Dumonceau et al.
ENDOSCOPY (2014)
Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers
Mu Li et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
A critical analysis of codon optimization in human therapeutics
Vincent P. Mauro et al.
TRENDS IN MOLECULAR MEDICINE (2014)
Gene therapy in pancreatic cancer
Si-Xue Liu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
Kathryn A. Whitehead et al.
NATURE COMMUNICATIONS (2014)
Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology
Uma Prabhakar et al.
CANCER RESEARCH (2013)
Specific transduction and labeling of pancreatic ducts by targeted recombinant viral infusion into mouse pancreatic ducts
Ping Guo et al.
LABORATORY INVESTIGATION (2013)
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
Lior Zangi et al.
NATURE BIOTECHNOLOGY (2013)
Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts
Anabel Jose et al.
ONCOTARGET (2013)
Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA
Ersin Akinci et al.
BIOCHEMICAL JOURNAL (2012)
In vivo genetic engineering of murine pancreatic beta cells mediated by single-stranded adeno-associated viral vectors of serotypes 6, 8 and 9
V. Jimenez et al.
DIABETOLOGIA (2011)
Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
Federico Mingozzi et al.
NATURE REVIEWS GENETICS (2011)
Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
Luigi Warren et al.
CELL STEM CELL (2010)
Effect of liposome size on peritoneal retention and organ distribution after intraperitoneal injection in mice
N. Mirahmadi et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2010)
Peritoneal retention of liposomes: Effects of lipid composition, PEG coating and liposome charge
S. Dadashzadeh et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
Akin Akinc et al.
MOLECULAR THERAPY (2010)
Revascularization of transplanted islets - Can it be improved?
Marcela Brissova et al.
DIABETES (2008)
Molecular composition of the peri-islet basement membrane in NOD mice: a barrier against destructive insulitis
H. F. Irving-Rodgers et al.
DIABETOLOGIA (2008)
Interleukin 2: from immunostimulation to immunoregulation and back again
Martin F. Bachmann et al.
EMBO REPORTS (2007)
Human peritoneal macrophage show functional characteristics of M-CSF-driven anti-inflammatory type 2 macrophages
Wei Xu et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes
Z Wang et al.
DIABETES (2006)
Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts
SA Loiler et al.
MOLECULAR THERAPY (2005)
Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo
AY Wang et al.
HUMAN GENE THERAPY (2004)
Codon bias and heterologous protein expression
C Gustafsson et al.
TRENDS IN BIOTECHNOLOGY (2004)
Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia
A Garcia-Ocaña et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Development of a destabilized firefly luciferase enzyme for measurement of gene expression
GM Leclerc et al.
BIOTECHNIQUES (2000)
Share Paper
