Indolizine: A Promising Framework for Developing a Diverse Array of C-H Functionalized Hybrids

C-H functionalized indolizines have emerged as a modern sustainable protocol, as it offers robust applications in the field of agriculture, medicine and pharmaceutical sciences. In recent times, a number of effective methods for the C-C, C-P and C-S bond formation via C-H functionalization of indolizines have been established. The present review article provides a thorough assessment of recent developments in the C-H functionalization of indolizines. The review has been categorized based on C-C, C-P and C-S bond formation using conventional as well as non-conventional methodologies. Moreover, the reaction mechanism has been discussed in elaborated form.

Automated summary

C-H functionalized indolizines have become a modern sustainable protocol with robust applications in agriculture, medicine, and pharmaceutical sciences. Recent developments in C-C, C-P, and C-S bond formation through C-H functionalization of indolizines have been assessed in this review article. The article categorizes the developments based on conventional and non-conventional methodologies and provides an in-depth discussion of the reaction mechanism.