Copper-Decorated Magnetite Polydopamine Composite (Fe3O4@PDA): An Effective and Durable Heterogeneous Catalyst for Pyranopyrazole Synthesis

Synthesis of pyranopyrazoles using heterogeneous catalysts is among the most executed synthetic approaches in organic chemistry and has attracted much attention because of the atom economy and environmentally benign issues. Magnetite dopamine-supported copper nanoparticles were created using a simple co-precipitation technique and characterized by Fourier-transform infrared spectroscopy (FTIR), x-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), and vibrating sample magnetometry (VSM). The catalytic activity of the Fe3O4@PDA/CuCl2 system was probed in the synthesis of structurally diverse pyranopyrazoles. It ' s worth mentioning that the catalyst could be used at low loadings to produce pyranopyrazoles with high to acceptable in the absence of an external reducing agent. Additionally, the produced heterogeneous catalyst can be reused (by extracting with an external magnet) in six subsequent cycles without suffering a significant loss in catalytic activity. The high efficiency of the derivatives from about 70 % to 98 %, as well as the fact that the TON)1000-2500( and TOF)1000-5000 h(-1)) have attained the optimal amount, indicate the catalyst's high efficiency.

Automated summary

Synthesis of pyranopyrazoles using heterogeneous catalysts is a commonly used method in organic chemistry. In this study, magnetite dopamine-supported copper nanoparticles were prepared and characterized. The Fe3O4@PDA/CuCl2 system demonstrated good catalytic activity and can be reused.