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The immediate and long-term effects of prenatal opioid exposure

Journal

FRONTIERS IN PEDIATRICS
Volume 10, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fped.2022.1039055

Keywords

neonatal abstinence syndrome; short-term effects; long-term outcomes; nutrition; growth trajectory; brain development; ophthalmologic disorders; physical therapy

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This article provides a overview of the long-term effects of antenatal opioid exposure on neonates and children, as well as quality improvement and research efforts to address this major public health concern.
The opioid epidemic has adversely affected neonates and children, yet the mechanisms by which it impacts this population are not well understood. Not only does prenatal opioid exposure result in short-term consequences shortly after birth, it also creates long-term sequelae that may predispose these children to physical, emotional, psychiatric, cognitive, and socioeconomic problems in the future. This article provides a scoping overview of the long-term effects of antenatal opioid exposure on neonates and children as well as quality improvement and research efforts to understand and mitigate this major public health concern.

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