Corneal Biomechanical Characteristics in Osteogenesis Imperfecta With Collagen Defect

Article Endocrinology & Metabolism

Risk of eye diseases in osteogenesis imperfecta - A nationwide, register-based cohort study

Marie Louise Lyster et al.

Summary: The study found that patients with Osteogenesis imperfecta (OI) have a higher risk of cataract, refractive disorders, glaucoma, vitreous hemorrhages, retinal detachment/ruptures, retinal diseases, and optic nerve disorders.

BONE (2022)

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Article Ophthalmology

Keratoconus: Diagnosis and Staging

Michael W. Belin et al.

Summary: The development of tomographic imaging has allowed for the recognition of early or subclinical ectatic disease, making it useful for screening refractive surgery patients. The screening tools utilized by tomographic imaging devices aid in diagnosing corneal disease, and the Belin ABCD staging and classification system can be used for earlier intervention and prevention of visual loss in keratoconus.

CORNEA (2022)

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Article Ophthalmology

Correlation of the Corvis Biomechanical Factor with tomographic parameters in keratoconus

Elias Flockerzi et al.

Summary: The purpose of this study is to investigate the relationship between corneal biomechanics and the severity of keratoconus (KC). The results show that there is a high correlation between the linear term of the Corvis Biomechanical Index (CBI beta) and tomographic parameters (anterior radius of curvature, posterior radius of curvature, and thinnest corneal thickness) in the KC population. This finding suggests that biomechanical characteristics can be used for classifying KC in the future.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2022)

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Article Ophthalmology

Effect of prostaglandin analogues on the biomechanical corneal properties in patients with open-angle glaucoma and ocular hypertension measured with dynamic scheimpflug analyzer

Marta Isabel Martinez-Sanchez et al.

Summary: The aim of this study was to evaluate the effect of topical prostaglandin treatment on the corneal biomechanical properties in treatment-naive patients with primary open-angle glaucoma or ocular hypertension. The results showed that the stress-strain index provided by Corvis ST significantly decreased after topical prostaglandin therapy, suggesting that the ocular hypotensive effect of prostaglandin treatment may be overestimated when measured using the Goldman Applanation Tonometry.

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2022)

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Article Biotechnology & Applied Microbiology

The relationship between axial length/corneal radius of curvature ratio and stress-strain index in myopic eyeballs: Using Corvis ST tonometry

Zhe Chu et al.

Summary: This study found a significant negative correlation between axial length/corneal radius of curvature ratio and stress-strain index (SSI). This correlation was observed in both patients without high myopia and patients with high myopia. However, SSI did not decrease with worsening myopia, but rather remained stable at a low level. These findings suggest the potential of analyzing dynamic changes in ocular wall stiffness during myopia development using in vivo corneal biomechanical parameters.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)

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Article Ophthalmology

Corneal Stiffness and Modulus of Normal-Tension Glaucoma in Chinese

Yunzhi Xu et al.

Summary: This study assessed and compared corneal biomechanics in normal-tension glaucoma (NTG), high-tension glaucoma (HTG), and normal controls. The results showed that the corneas of NTG patients were softer than those of HTG patients and controls, which was associated with thinner corneal thickness.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2022)

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Article Ophthalmology

Correlation of the Corvis Biomechanical Factor with tomographic parameters in keratoconus

Paula Jaye Doyle et al.

Summary: This study found a strong correlation between the linear term of the Corvis Biomechanical Index and KC severity based on corneal tomography, proposing a new scale CBiF based on biomechanical characteristics in KC for potential use in biomechanical KC classification in the future.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2022)

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Article Biotechnology & Applied Microbiology

Stress-Strain Index Map: A New Way to Represent Corneal Material Stiffness

Haixia Zhang et al.

Summary: The study introduced a new method to map the mechanical stiffness of healthy and keratoconic corneas based on collagen fibril distribution trends. The results showed significant reductions in SSI values inside the cone in keratoconic corneas, with the reductions dependent on the extent of the disease.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Article Multidisciplinary Sciences

Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile

Sharon D'Souza et al.

Summary: The study found significant changes in immune cell subsets and inflammatory factor profile on the ocular surface of keratoconus (KC) patients, indicating a distinct immuno-inflammatory component in KC pathogenesis. These alterations may be related to disease severity, allergy, eye rubbing, providing an additional therapeutic target for KC management.

SCIENTIFIC REPORTS (2021)

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Article Ophthalmology

Corneal Stiffness Parameters Are Predictive of Structural and Functional Progression in Glaucoma Suspect Eyes

Ayub Qassim et al.

Summary: This study found that in glaucoma suspect eyes, corneal stiffness parameters and corneal thickness have a synergistic effect on the risk of disease progression, with eyes that have stiffer and thinner corneas being more likely to experience thinning of the retinal nerve fiber layer, ganglion cell-inner plexiform layer, and visual field damage.

OPHTHALMOLOGY (2021)

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Article Ophthalmology

Abnormal corneal properties in osteogenesis imperfecta and glaucoma: a case series

Emer Doolan et al.

Summary: This study aimed to investigate ocular examination and genetic studies in a family with OI and POAG, finding that corneal properties were reduced in members affected with OI. Patients with OI have a significant risk of developing POAG.

BMJ OPEN OPHTHALMOLOGY (2021)

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Article Ophthalmology

Corneal biomechanics and biomechanically corrected intraocular pressure in primary open-angle glaucoma, ocular hypertension and controls

Riccardo Vinciguerra et al.

BRITISH JOURNAL OF OPHTHALMOLOGY (2020)

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Review Ophthalmology

Scleral structure and biomechanics

Craig Boote et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2020)

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Article Ophthalmology

Biomechanical contribution of the sclera to dynamic corneal response in air-puff induced deformation in human donor eyes

B. Audrey Nguyen et al.

EXPERIMENTAL EYE RESEARCH (2020)

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Article Ophthalmology

Anterior Segment Findings in Patients With Osteogenesis Imperfecta: A Case-Control Study

Ali Keles et al.

CORNEA (2020)

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Article Ophthalmology

Calculating Sensitivity, Specificity, and Predictive Values for Correlated Eye Data

Gui-Shuang Ying et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2020)

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Article Biotechnology & Applied Microbiology

Determination of Corneal Biomechanical Behavior in-vivo for Healthy Eyes Using CorVis ST Tonometry: Stress-Strain Index

Ashkan Eliasy et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)

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Article Chemistry, Multidisciplinary

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ADVANCED MATERIALS (2019)

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Article Endocrinology & Metabolism

Health-related quality of life in children with osteogenesis imperfecta: a large-sample study

Y. Song et al.

OSTEOPOROSIS INTERNATIONAL (2019)

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Article Genetics & Heredity

Bilateral giant retinal tears in Osteogenesis Imperfecta

Paolo Scollo et al.

BMC MEDICAL GENETICS (2018)

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Article Ophthalmology

An Early Finding of Keratoconus: Increase in Corneal Densitometry

Mustafa Koc et al.

CORNEA (2018)

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Article Ophthalmology

Altered corneal biomechanical properties in children with osteogenesis imperfecta

Lisa M. Lagrou et al.

JOURNAL OF AAPOS (2018)

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Review Ophthalmology

Biomechanics and structure of the cornea: implications and association with corneal disorders

Jiaonan Ma et al.

SURVEY OF OPHTHALMOLOGY (2018)

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Article Ophthalmology

Collagen I Defect Corneal Profiles in Osteogenesis Imperfecta

Otavio A. Magalhaes et al.

CORNEA (2018)

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Article Endocrinology & Metabolism

Osteogenesis imperfecta and the teeth, eyes, and earsa study of non-skeletal phenotypes in adults

J. D. Hald et al.

OSTEOPOROSIS INTERNATIONAL (2018)

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Article Ophthalmology

In Vivo Early Corneal Biomechanical Changes After Corneal Cross-linking in Patients With Progressive Keratoconus

Riccardo Vinciguerra et al.

JOURNAL OF REFRACTIVE SURGERY (2017)

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Article Ophthalmology

Introduction of Two Novel Stiffness Parameters and Interpretation of Air Puff-Induced Biomechanical Deformation Parameters With a Dynamic Scheimpflug Analyzer

Cynthia J. Roberts et al.

JOURNAL OF REFRACTIVE SURGERY (2017)

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Article Ophthalmology

Integration of Scheimpflug-Based Corneal Tomography and Biomechanical Assessments for Enhancing Ectasia Detection

Renato Ambrosio et al.

JOURNAL OF REFRACTIVE SURGERY (2017)

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Article Ophthalmology

Biomechanical Characterization of Subclinical Keratoconus Without Topographic or Tomographic Abnormalities

Riccardo Vinciguerra et al.

JOURNAL OF REFRACTIVE SURGERY (2017)

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Article Computer Science, Interdisciplinary Applications

Development and validation of a correction equation for Corvis tonometry

Akram Abdelazim Joda et al.

COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING (2016)

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Article Biophysics

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Journal of Biophotonics (2016)

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Article Ophthalmology

Detection of Keratoconus With a New Biomechanical Index

Riccardo Vinciguerra et al.

JOURNAL OF REFRACTIVE SURGERY (2016)

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Article Ophthalmology

Influence of Pachymetry and Intraocular Pressure on Dynamic Corneal Response Parameters in Healthy Patients

Riccardo Vinciguerra et al.

JOURNAL OF REFRACTIVE SURGERY (2016)

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Review Medicine, General & Internal

Osteogenesis imperfecta

Antonella Forlino et al.

LANCET (2016)

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Article Genetics & Heredity

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AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2016)

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Article Genetics & Heredity

Osteogenesis imperfecta: Clinical diagnosis, nomenclature and severity assessment

F. S. Van Dijk et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2014)

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Article Ophthalmology

Discriminant Value of Custom Ocular Response Analyzer Waveform Derivatives in Keratoconus

Katie M. Hallahan et al.

OPHTHALMOLOGY (2014)

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Article Pediatrics

Cyclic Pamidronate Infusion for Neonatal-onset Osteogenesis Imperfecta

Chia-Hsuan Lin et al.

PEDIATRICS AND NEONATOLOGY (2014)

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Article Ophthalmology

Biomechanical Characterization of Keratoconus Corneas Ex Vivo With Brillouin Microscopy

Giuliano Scarcelli et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

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Article Ophthalmology

Normative Values for Corneal Densitometry Analysis by Scheimpflug Optical Assessment

Sorcha Ni Dhubhghaill et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

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Article Endocrinology & Metabolism

New Genes in Bone Development: What's New in Osteogenesis Imperfecta

Joan C. Marini et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

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Article Ophthalmology

Corneal Densitometry as an Indicator of Corneal Health

Ahmad Muneer Otri et al.

OPHTHALMOLOGY (2012)

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Article Ophthalmology

IOP-Induced Lamina Cribrosa Displacement and Scleral Canal Expansion: An Analysis of Factor Interactions Using Parameterized Eye-Specific Models

Ian A. Sigal et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

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Article Ophthalmology

Corneal Biomechanical Metrics and Anterior Segment Parameters in Mild Keratoconus

Bruno M. Fontes et al.

OPHTHALMOLOGY (2010)

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Review Orthopedics

Osteogenesis imperfecta: Diagnosis and treatment

Gheorghe Burnei et al.

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS (2008)

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Review Ophthalmology

What biomechanical properties of the cornea are relevant for the clinician?

Aachal Kotecha

SURVEY OF OPHTHALMOLOGY (2007)

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Article Ophthalmology

Corneal-thickness spatial profile and corneal-volume distribution: Tomographic indices to detect keratoconus

Renato Ambrosio et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2006)

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Review Ophthalmology

Human corneal thickness and its impact on intraocular pressure measures: A review and meta-analysis approach

MJ Doughty et al.

SURVEY OF OPHTHALMOLOGY (2000)

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Corneal Biomechanical Characteristics in Osteogenesis Imperfecta With Collagen Defect

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