COVID-19 and thyroid function: What do we know so far?

Article Endocrinology & Metabolism

Heterozygote Advantage of the Type II Deiodinase Thr92Ala Polymorphism on Intrahospital Mortality of COVID-19

Fabyan Esberard de Lima Beltrao et al.

Summary: Research on Thr92Ala-DIO2 polymorphism in COVID-19 patients showed that the Thr/Ala genotype is associated with lower intrahospital mortality rates, indicating a protective role of this genotype.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Add to Collection

Review Endocrinology & Metabolism

SARS-CoV-2 vaccine-associated subacute thyroiditis: insights from a systematic review

S. Ippolito et al.

Summary: This study reviewed subacute thyroiditis (SAT) cases following SARS-CoV-2 vaccination. It found that most SAT cases occurred in women, and the majority of patients experienced thyrotoxicosis. Corticosteroids were used in some treated patients. Patients with a history of thyroid disease were more likely to develop SAT after receiving mRNA vaccines.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2022)

Add to Collection

Article Endocrinology & Metabolism

Euthyroid sick syndrome as an early surrogate marker of poor outcome in mild SARS-CoV-2 disease

C. Sparano et al.

Summary: This study aims to evaluate the significance of ESS in hospitalized mild COVID-19 patients. The research found that low fT3 levels serve as a valid predictor of unfavorable outcomes in COVID-19 patients.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2022)

Add to Collection

Letter Endocrinology & Metabolism

COVID-19 targets human adrenal glands

Waldemar Kanczkowski et al.

LANCET DIABETES & ENDOCRINOLOGY (2022)

Add to Collection

Article Medicine, Research & Experimental

COVID-19 induced hypoparathyroidism: A case report

Vasiliki Epameinondas Georgakopoulou et al.

Summary: SARS-CoV-2 infection can cause hypoparathyroidism, but its effects on the parathyroid glands have not been extensively studied.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2022)

Add to Collection

Article Endocrinology & Metabolism

Is non-thyroidal illness syndrome (NTIS) a clinical predictor of COVID-19 mortality in critically ill oldest old patients?

C. Okoye et al.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2022)

Add to Collection

Review Endocrinology & Metabolism

SARS-CoV-2 vaccine may trigger thyroid autoimmunity: real-life experience and review of the literature

R. M. Ruggeri et al.

Summary: It is found that SARS-CoV-2 vaccines may trigger autoimmune reactions and lead to permanent or transient thyroid dysfunction in susceptible individuals.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2022)

Add to Collection

Review Endocrinology & Metabolism

Thyroid Inconveniences With Vaccination Against SARS-CoV-2: The Size of the Matter. A Systematic Review

Verdiana Caironi et al.

Summary: After COVID-19 vaccination, reports of thyroid disease possibly related to the vaccine have been increasing. However, the size and quality of published data on this topic are limited. Thyroid disorders may occur within 2 months after vaccination, with Graves' disease and subacute thyroiditis appearing to be more frequent.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection

Review Nutrition & Dietetics

Obesity and Infection: What Have We Learned From the COVID-19 Pandemic

Emilia Vassilopoulou et al.

Summary: This narrative review investigated the relationship between COVID-19 and obesity and found that obesity increases the risk of severe complications, ICU admission, intubation, and mortality. Patients with a higher BMI are more vulnerable to SARS-CoV-2 infection, with more severe illness and higher mortality. Therefore, maintaining a healthy body weight is important for preventing acute complications, and overweight and obese patients should be closely monitored during the COVID-19 pandemic.

FRONTIERS IN NUTRITION (2022)

Add to Collection

Article Endocrinology & Metabolism

The potential impact of COVID-19 on thyroid gland volumes among COVID-19 survivors

Emre Urhan et al.

Summary: This study investigated the effects of COVID-19 on the thyroid gland among survivors and found that at 6 months after acute infection, COVID-19 survivors had smaller thyroid gland volume compared to healthy controls, but only a few of the survivors had abnormal thyroid function.

ENDOCRINE (2022)

Add to Collection

Letter Endocrinology & Metabolism

Subacute thyroiditis in a patient infected with SARS-COV-2: an endocrine complication linked to the COVID-19 pandemic

Rosaria Maddalena Ruggeri et al.

Summary: SAT is an inflammatory thyroid disorder of viral origin, commonly preceded by an upper respiratory tract infection. It is important to diagnose and treat the disease promptly to prevent complications and long-term sequelae.

HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (2021)

Add to Collection

Article Virology

An update on the origin of SARS-CoV-2: Despite closest identity, bat (RaTG13) and pangolin derived coronaviruses varied in the critical binding site and O-linked glycan residues

Jeevan Malaiyan et al.

Summary: SARS-CoV-2 initially occurred in Wuhan, China in December 2019, spreading globally by June 23, 2020. The virus is believed to have originated from bats and pangolins, but the exact transmission routes remain unclear. Further research is needed to understand the role of pangolins and bats in the spread of SARS-CoV-2.

JOURNAL OF MEDICAL VIROLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid Function Analysis in 50 Patients with COVID-19: A Retrospective Study

Min Chen et al.

Summary: This study found that levels of TSH and TT3 in COVID-19 patients were significantly lower compared to healthy controls and non-COVID-19 pneumonia patients, with a positive correlation between the severity of COVID-19 and the decrease in TSH and TT3 levels.

THYROID (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients

Jiyeon Ahn et al.

Summary: This study found that thyroid dysfunction is common in COVID-19 patients, with lower TSH and T3 levels in severe cases. Decreased T3 levels may serve as a prognostic marker for outcomes in COVID-19 patients.

ENDOCRINOLOGY AND METABOLISM (2021)

Add to Collection

Review Gastroenterology & Hepatology

COVID-19 and the liver: What do we know so far?

Prashant Nasa et al.

Summary: The COVID-19 pandemic has placed unprecedented pressure on public health and healthcare systems, particularly affecting patients with pre-existing liver diseases, hepatocellular carcinoma, or those who have received a liver transplant. Research has shown that patients with chronic liver diseases are at higher risk for severe COVID-19.

WORLD JOURNAL OF HEPATOLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Detection of SARS-COV-2 receptor ACE-2 mRNA in thyroid cells: a clue for COVID-19-related subacute thyroiditis

M. Rotondi et al.

Summary: The study demonstrated the expression of ACE-2 receptor mRNA in thyroid follicular cells, making them a potential target for SARS-COV-2 entry. Future clinical studies in COVID-19 patients will be needed to further understand the impact of SARS-CoV-2 infection on the thyroid.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2021)

Add to Collection

Article Medicine, Legal

Clinicopathologic Features of COVID-19: A Case Report and Value of Forensic Autopsy in Studying SARS-CoV-2 Infection

Liang Ren et al.

Summary: This case study presents a 53-year-old female patient who unfortunately passed away due to respiratory failure and secondary bacterial infection caused by COVID-19. Autopsy findings revealed that the SARS-CoV-2 virus can infect multiple organs, with lung pathology characterized by diffuse alveolar damage. The importance of forensic autopsy and clinicopathological correlation in better understanding the pathogenesis of COVID-19 is highlighted in this report.

AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Sick Euthyroid Syndrome on Presentation of Patients With COVID-19: A Potential Marker for Disease Severity

Yair Schwarz et al.

Summary: This retrospective cohort study found that free triiodothyronine (FT3) can serve as a prognostic tool for disease severity and death in the early presentation of COVID-19. Patients in the lowest tertile of FT3 had significantly higher rates of mortality, mechanical ventilation, and intensive care unit admission. FT3 remained a significant independent predictor of death even after adjusting for various factors.

ENDOCRINE PRACTICE (2021)

Add to Collection

Review Endocrinology & Metabolism

Impact of COVID-19 on the thyroid gland: an update

Lorenzo Scappaticcio et al.

Summary: COVID-19 has been shown to have a potential impact on the thyroid gland and the entire hypothalamic-pituitary-thyroid (HPT) axis. Evidence suggests that COVID-19-related thyroid disorders include thyrotoxicosis, hypothyroidism, and nonthyroidal illness syndrome. Treatment plans for thyroid cancer are also shifting towards more teleconsultations due to the pandemic.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2021)

Add to Collection

Review Endocrinology & Metabolism

An update on non-thyroidal illness syndrome

E. Fliers et al.

Summary: NTIS is a syndrome characterized by changes in serum thyroid hormones concentrations in severe illnesses, particularly a decrease in serum T3 levels, which is correlated with disease severity and outcomes. The role of (parenteral) feeding in critical illness as a major determinant of NTIS and clinical outcome has been recognized in recent years. Studies have shown that tissue thyroid hormone concentrations during NTIS may not correlate with serum levels, highlighting the importance of organ-specific thyroid transporters, receptors, and deiodinases.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2021)

Add to Collection

Article Endocrinology & Metabolism

The spectrum of thyroid function tests during hospitalization for SARS COV-2 infection

Irene Campi et al.

Summary: Alterations in thyroid function tests were observed in COVID-19 patients, with some showing normal TFTs and others having low TSH levels correlated with elevated CRP, cortisol, and IL-6 levels. This suggests a potential impact of cytokine storm induced by SARS-CoV-2 on thyroid function.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2021)

Add to Collection

Article Medicine, General & Internal

The prognostic impact of thyroid disorders on the clinical severity of COVID-19: Results of single-centre pandemic hospital

Mehmet Guven et al.

Summary: This study found that severe thyroid hormonal disorders were more common in critically ill COVID-19 patients. Free triiodothyronine (FT3) level at hospital admission may serve as a potential prognostic marker of COVID-19 patients. Thyroid nodules may be associated with severe COVID-19 disease.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

Add to Collection

Article Immunology

Mutations in SARS-CoV-2; Consequences in structure, function, and pathogenicity of the virus

Behnaz Bakhshandeh et al.

Summary: The third pandemic of coronavirus infection, COVID-19, started recently in China. The main pathogenesis includes severe pneumonia, with various factors potentially influencing mortality and infection rates. Mutations and genetic variabilities of the virus, along with host genetic susceptibility, can impact the clinical features of COVID-19.

MICROBIAL PATHOGENESIS (2021)

Add to Collection

Article Cell Biology

Thyroid dysfunction may be associated with poor outcomes in patients with COVID-19

Yan Zhang et al.

Summary: The study found that COVID-19 patients with thyroid dysfunction had higher levels of inflammation and cardiac injury markers, were more likely to develop a severe subtype of the disease, had a higher mortality rate during hospitalization, and required a longer hospitalization duration.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Suppression of the hypothalamic-pituitary-thyroid axis is associated with the severity of prognosis in hospitalized patients with COVID-19

Juan Zheng et al.

Summary: This study suggests that the suppression of the HPT axis could be a common complication in COVID-19 patients and is an indicator of the severity of prognosis. Among COVID-19 patients with different types of thyroid dysfunction, mild to moderate NTIS and severe NTIS have a higher risk of severe outcomes compared to subclinical hypothyroidism.

BMC ENDOCRINE DISORDERS (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid Function Abnormalities in COVID-19 Patients

Weibin Wang et al.

Summary: Thyroid function abnormalities are common in COVID-19 patients, especially in severe cases. This might be partially explained by nonthyroidal illness syndrome.

FRONTIERS IN ENDOCRINOLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Role of non-thyroidal illness syndrome in predicting adverse outcomes in COVID-19 patients predominantly of mild-to-moderate severity

David Tak Wai Lui et al.

Summary: This study found that the non-thyroidal illness syndrome was not uncommon even in mild-to-moderate COVID-19 patients. NTIS on admission could independently predict clinical deterioration in COVID-19, regardless of SARS-CoV-2 viral load, age, and markers of inflammation and tissue injury.

CLINICAL ENDOCRINOLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Low FT3 is an independent marker of disease severity in patients hospitalized for COVID-19

Aditya Dutta et al.

Summary: The study found that functional thyroid abnormalities (low FT3 and low TSH) are commonly seen in hospitalized patients with COVID-19, and low FT3 is independently predictive of the severity of COVID-19.

ENDOCRINE CONNECTIONS (2021)

Add to Collection

Article Medicine, General & Internal

Thyroid Disfunction in Critically Ill COVID-19 Patients. Relationship with In-Hospital Mortality

Maria Antonieta Ballesteros Vizoso et al.

Summary: By analyzing the thyroid profile in critically ill COVID-19 patients, variables associated with mortality and the predictive ability of mortality were identified. The study found that fT4 on day 5 after ICU admission was associated with in-hospital mortality.

JOURNAL OF CLINICAL MEDICINE (2021)

Add to Collection

Article Endocrinology & Metabolism

Two Cases of Graves' Disease Following SARS-CoV-2 Vaccination: An Autoimmune/Inflammatory Syndrome Induced by Adjuvants

Olga Vera-Lastra et al.

Summary: Two female health care workers developed clinical manifestations of thyroid hyperactivity, increased thyroid hormone levels, suppressed thyroid-stimulating hormone, and elevated antithyroid antibodies three days after receiving a SARS-CoV-2 vaccine. This indicates a potential link between SARS-CoV-2 vaccination and the onset of autoimmune thyroid diseases like Graves' disease.

THYROID (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid hormone alterations in critically and non-critically ill patients with SARS-CoV-2 infection

Dimitra Argyro Vassiliadi et al.

Summary: NTIS pattern is common in both ICU and ward patients regardless of SARS-CoV-2 infection, while thyrotoxicosis pattern is less frequently observed with similar frequency between patients with and without COVID-19. Hypothyroidism pattern is rare in COVID-19 patients. It is suggested that thyroid hormone monitoring in COVID-19 should not differ from other critically ill patients.

ENDOCRINE CONNECTIONS (2021)

Add to Collection

Article Endocrinology & Metabolism

Association between Thyroid Function and Prognosis of COVID-19: A Retrospective Observational Study

Shan Lang et al.

Summary: This study revealed that a low FT3 state is associated with an increased risk of in-hospital mortality for COVID-19 patients. Non-survivors showed lower serum levels of TSH and FT3 than survivors, with FT3 level negatively correlating with the risk of death. Thyroid function may play a role in the prognosis of COVID-19 patients.

ENDOCRINE RESEARCH (2021)

Add to Collection

Article Endocrinology & Metabolism

Activation of Type I and Type II Interferon Signaling in SARS-CoV-2-Positive Thyroid Tissue of Patients Dying from COVID-19

Anello Marcello Poma et al.

Summary: COVID-19 can directly infect the thyroid gland, leading to immune response activation and potential thyroid dysfunction.

THYROID (2021)

Add to Collection

Article Endocrinology & Metabolism

The Association of Thyroid Hormone Changes with Inflammatory Status and Prognosis in COVID-19

Ceyda Dincer Yazan et al.

Summary: In this study, 34.1% of COVID-19 patients were found to have normal thyroid function, with shorter hospitalization, lower oxygen demand, and lower ICU admission rates, and none of them died. Additionally, evaluation of thyroid function during COVID-19 infection may provide insights into disease prognosis.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2021)

Add to Collection

Article Multidisciplinary Sciences

Viral infiltration of pancreatic islets in patients with COVID-19

Charlotte Steenblock et al.

Summary: This study comprehensively analyzed pancreatic tissues from COVID-19 patients and found detectable SARS-CoV-2 viral infiltration in beta-cells, potentially contributing to metabolic dysregulation. Even in the absence of overt new-onset diabetes, viral infection of pancreatic beta-cells may lead to varying degrees of metabolic abnormalities.

NATURE COMMUNICATIONS (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid function in COVID-19 and the association with cytokine levels and mortality

Clara Lundetoft Clausen et al.

Summary: This study suggests that fluctuations of TSH levels in patients with COVID-19 may be influenced by circulating IL-8, IL-10, IL-15, IP-10, and GM-CSF, as previously described in autoimmune thyroid diseases. However, TSH levels were not associated with 30- or 90-day mortality in COVID-19 patients.

ENDOCRINE CONNECTIONS (2021)

Add to Collection

Article Endocrinology & Metabolism

Correlation between inflammatory parameters and pituitary-thyroid axis in patients with COVID-19

Veronica Ilera et al.

Summary: This study evaluated the correlation between thyroid hormones and inflammatory markers, as well as the association with disease outcome in hospitalized COVID-19 patients. The results showed that T3 and T3/T4 were inversely correlated with inflammatory markers, and a low T3/T4 ratio was associated with disease severity and poor prognosis.

ENDOCRINE (2021)

Add to Collection

Article Endocrinology & Metabolism

Higher SARS-CoV-2 viral loads correlated with smaller thyroid volumes on ultrasound among male COVID-19 survivors

David Tak Wai Lui et al.

Summary: Thyroid dysfunction, including thyroiditis, is common in COVID-19 patients, but all abnormal thyroid function tests during acute COVID-19 recovered upon follow-up. Higher SARS-CoV-2 viral load on presentation were associated with smaller thyroid volumes, especially in men. There was no increased rate of ultrasonographic features suggestive of thyroiditis in COVID-19 survivors.

ENDOCRINE (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Assessment of thyroid function of newly diagnosed SARS-CoV-2 infected patients in Nigeria

Chika Juliet Okwor et al.

Summary: The study found that COVID-19 patients had significantly higher plasma levels of FT3 and TSH compared to controls, although most of them were euthyroid. However, some COVID-19 patients did exhibit thyroid function abnormalities, indicating the importance of monitoring thyroid function during and after COVID-19 treatment.

PAN AFRICAN MEDICAL JOURNAL (2021)

Add to Collection

Review Endocrinology & Metabolism

COVID-19 and Thyroid Diseases: A Bidirectional Impact

Leonidas H. Duntas et al.

Summary: COVID-19 infection is associated with triggering Graves' disease and subacute thyroiditis, and possibly hypothyroidism. Studies indicate that thyroid function may influence susceptibility to COVID-19 infection.

JOURNAL OF THE ENDOCRINE SOCIETY (2021)

Add to Collection

Article Endocrinology & Metabolism

Subacute Thyroiditis in COVID-19 Patients

Saeed Sohrabpour et al.

Summary: This study reported 6 cases of SAT following COVID-19 infection, showing typical features of SAT in clinical manifestations and laboratory evaluations. All patients had negative COVID-19 PCR test results but positive serological tests for COVID-19.

EUROPEAN THYROID JOURNAL (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid Function Before, During, and After COVID-19

Bernard Khoo et al.

Summary: Most patients with COVID-19 present with euthyroidism. Mild reductions in TSH and FT4 were observed in COVID-19 patients, consistent with a nonthyroidal illness syndrome. In survivors of COVID-19, thyroid function tests at follow-up returned to baseline.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

Add to Collection

Article Endocrinology & Metabolism

Thyroid hormone concentrations in severely or critically ill patients with COVID-19

W. Gao et al.

Summary: This study aimed to investigate the characteristics of thyroid hormone levels in COVID-19 patients, finding significantly lower free T3 concentrations in severe patients, with reduced FT3 independently predicting increased all-cause mortality in patients with severe COVID-19.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2021)

Add to Collection

Article Emergency Medicine

Identifying critically ill patients at risk of death from coronavirus disease

Wei Guo et al.

Summary: This study included 121 critically ill patients, with 28.9% (35/121) of them dying in the hospital. Non-survivors were older and more likely to develop acute organ dysfunction, with higher SOFA and qSOFA scores. Twelve useful biomarkers for predicting in-hospital mortality were identified, such as NLR, FT3, and ferritin, suggesting their potential as powerful predictors for fatal outcomes in COVID-19 patients.

WORLD JOURNAL OF EMERGENCY MEDICINE (2021)

Add to Collection

Article Virology

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2

Zhixin Liu et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Add to Collection

Article Multidisciplinary Sciences

A new coronavirus associated with human respiratory disease in China

Fan Wu et al.

NATURE (2020)

Add to Collection

Article Endocrinology & Metabolism

ENDOCRINOLOGY IN THE TIME OF COVID-19 Management of hyperthyroidism and hypothyroidism

Kristien Boelaert et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2020)

Add to Collection

Article Endocrinology & Metabolism

ENDOCRINOLOGY IN THE TIME OF COVID-19 Management of adrenal insufficiency

Wiebke Arlt et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2020)

Add to Collection

Article Respiratory System

Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis

Wei-jie Guan et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

Add to Collection

Article Obstetrics & Gynecology

Coronavirus disease-19 and fertility: viral host entry protein expression in male and female reproductive tissues

Kate E. Stanley et al.

FERTILITY AND STERILITY (2020)

Add to Collection

Article Endocrinology & Metabolism

Subacute Thyroiditis After Sars-COV-2 Infection

Alessandro Brancatella et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)

Add to Collection

Article Medicine, General & Internal

Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study

Tao Chen et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

Add to Collection

Article Infectious Diseases

Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues

Meng-Yuan Li et al.

INFECTIOUS DISEASES OF POVERTY (2020)

Add to Collection

Letter Endocrinology & Metabolism

SARS-CoV-2: a potential trigger for subacute thyroiditis? Insights from a case report

S. Ippolito et al.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2020)

Add to Collection

Letter Immunology

Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases

Aristo Vojdani et al.

CLINICAL IMMUNOLOGY (2020)

Add to Collection

Review Endocrinology & Metabolism

Endocrine Significance of SARS-CoV-2's Reliance on ACE2

Eric Lazartigues et al.

ENDOCRINOLOGY (2020)

Add to Collection

Article Endocrinology & Metabolism

Thyrotoxicosis in patients with COVID-19: the THYRCOV study

Andrea Lania et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2020)

Add to Collection

Letter Endocrinology & Metabolism

A case of subacute thyroiditis associated with Covid-19 infection

E. Asfuroglu Kalkan et al.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2020)

Add to Collection

Letter Endocrinology & Metabolism

SARS-CoV-2-related atypical thyroiditis

Ilaria Muller et al.

LANCET DIABETES & ENDOCRINOLOGY (2020)

Add to Collection

Article Endocrinology & Metabolism

Is Subacute Thyroiditis an Underestimated Manifestation of SARS-CoV-2 Infection? Insights From a Case Series

Alessandro Brancatella et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)

Add to Collection

Article Virology

Combination of four clinical indicators predicts the severe/critical symptom of patients infected COVID-19

Liping Sun et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

Add to Collection

Review Endocrinology & Metabolism

Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management

Philippe Caron

ANNALES D ENDOCRINOLOGIE (2020)

Add to Collection

Letter Medicine, Research & Experimental

Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial

Constantinos Pantos et al.

TRIALS (2020)

Add to Collection

Article Endocrinology & Metabolism

Outcomes of Patients With Hypothyroidism and COVID-19: A Retrospective Cohort Study

Maaike van Gerwen et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Add to Collection

Article Endocrinology & Metabolism

Euthyroid Sick Syndrome in Patients With COVID-19

Runmei Zou et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Add to Collection

Review Biology

Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?

Filiberto Fausto Mottola et al.

LIFE-BASEL (2020)

Add to Collection

Review Clinical Neurology

SARS coronavirus 2 and central nervous system manifestations: causation, relation, or coexistence? a case series study and literature review

Seyed Abdolhadi Daneshi et al.

BRITISH JOURNAL OF NEUROSURGERY (2020)

Add to Collection

Review Medicine, General & Internal

COVID-19-associated collapsing glomerulopathy: a report of two cases and literature review

Hassan Izzedine et al.

INTERNAL MEDICINE JOURNAL (2020)

Add to Collection

Review Endocrinology & Metabolism

The Impact of Diabetes Mellitus in COVID-19: A Mechanistic Review of Molecular Interactions

Habib Yaribeygi et al.

JOURNAL OF DIABETES RESEARCH (2020)

Add to Collection

Article Medicine, General & Internal

Subacute thyroiditis associated with COVID-19

Shaikh Abdul Matin Mattar et al.

BMJ CASE REPORTS (2020)

Add to Collection

Article Medicine, General & Internal

Subacute thyroiditis as a presenting manifestation of COVID-19: a report of an exceedingly rare clinical entity

Uddalak Chakraborty et al.

BMJ CASE REPORTS (2020)

Add to Collection

Article Respiratory System

Pediatric airway compromise due to thyroid storm associated with influenza A infection: A case report

Taiki Higaki et al.

RESPIRATORY MEDICINE CASE REPORTS (2020)

Add to Collection

Article Medicine, General & Internal

Possible role of hypothyroidism in the prognosis of COVID-19

Morteza Daraei et al.

INTERNAL MEDICINE JOURNAL (2020)

Add to Collection

Article Physiology

The Role of Thyroid Hormone in the Innate and Adaptive Immune Response during Infection

Julia Rubingh et al.

COMPREHENSIVE PHYSIOLOGY (2020)

Add to Collection

Review Endocrinology & Metabolism

Deiodinases and their intricate role in thyroid hormone homeostasis

Cristina Luongo et al.

NATURE REVIEWS ENDOCRINOLOGY (2019)

Add to Collection

Article Endocrinology & Metabolism

Downregulation of Type 3 Deiodinase in the Hypothalamus During Inflammation

Emmely M. de Vries et al.

THYROID (2019)

Add to Collection

Review Endocrinology & Metabolism

ANNIVERSARY REVIEW Antithyroid drug therapy: 70 years later

Henry B. Burch et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Reverse triiodothyronine (rT3) attenuates ischemia-reperfusion injury

Leena Rastogi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Add to Collection

Review Endocrinology & Metabolism

Thyroid hormone metabolism in innate immune cells

Anne H. van der Spek et al.

JOURNAL OF ENDOCRINOLOGY (2017)

Add to Collection

Review Medicine, General & Internal

Hypothyroidism

Layal Chaker et al.

LANCET (2017)

Add to Collection

Article Oncology

Insufficient hypothalamic angiotensin-converting enzyme 2 is associated with hypertension in SHR rats

Kun Wang et al.

ONCOTARGET (2017)

Add to Collection

Review Cell Biology

Thyroid Hormones, Oxidative Stress, and Inflammation

Antonio Mancini et al.

MEDIATORS OF INFLAMMATION (2016)

Add to Collection

Article Cell Biology

Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats

Shu-Yan Dai et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Add to Collection

Review Critical Care Medicine

Thyroid Storm: An Updated Review

Maguy Chiha et al.

JOURNAL OF INTENSIVE CARE MEDICINE (2015)

Add to Collection

Article Medical Laboratory Technology

Patients Infected with Avian Influenza A H7N9 Virus have Abnormally Low Thyroid Hormone Levels

Jie Zhang et al.

CLINICAL LABORATORY (2014)

Add to Collection

Article Endocrinology & Metabolism

NFκB Signaling Is Essential for the Lipopolysaccharide-Induced Increase of Type 2 Deiodinase in Tanycytes

E. M. de Vries et al.

ENDOCRINOLOGY (2014)

Add to Collection

Article Endocrinology & Metabolism

Subacute Thyroiditis: Clinical Presentation and Long Term Outcome

Assim A. Alfadda et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2014)

Add to Collection

Article Endocrinology & Metabolism

Thyroid Hormones as Modulators of Immune Activities at the Cellular Level

Paolo De Vito et al.

THYROID (2011)

Add to Collection

Article Cardiac & Cardiovascular Systems

H1N1 infection-induced thyroid storm

Salim Alawi Baharoon

ANNALS OF THORACIC MEDICINE (2010)

Add to Collection

Article Biochemistry & Molecular Biology

Endocrine cells of the adenohypophysis in severe acute respiratory syndrome (SARS)

Lan Wei et al.

BIOCHEMISTRY AND CELL BIOLOGY (2010)

Add to Collection

Letter Endocrinology & Metabolism

Subacute thyroiditis following the H1N1 vaccine

C. M. Girgis et al.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2010)

Add to Collection

Article Endocrinology & Metabolism

Subacute thyroiditis in the course of novel H1N1 influenza infection

Georgios Dimos et al.

ENDOCRINE (2010)

Add to Collection

Article Neurosciences

Involvement of Thyroid Hormones in the Alterations of T-Cell Immunity and Tumor Progression Induced by Chronic Stress

Luciana Romina Frick et al.

BIOLOGICAL PSYCHIATRY (2009)

Add to Collection

Article Endocrinology & Metabolism

Expression of thyroid hormone transporters during critical illness

Liese Mebis et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2009)

Add to Collection

Article Endocrinology & Metabolism

Fulminant meningococcal meningitis and sepsis associated with severe hypothyroidism caused by autoimmune (Hashimoto) thyreoiditis

D. Mayer et al.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2009)

Add to Collection

Article Endocrinology & Metabolism

Parameters of respiratory burst and arachidonic acid metabolism in polymorphonuclear granulocytes from patients with various thyroid diseases

J. Szabó et al.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2009)

Add to Collection

Article Endocrinology & Metabolism

Skeletal muscle deiodinase type 2 regulation during illness in mice

J. Kwakkel et al.

JOURNAL OF ENDOCRINOLOGY (2009)

Add to Collection

Article Endocrinology & Metabolism

Preliminary evidence of immune function modulation by thyroid hormones in healthy men and women aged 55-70 years

Clare F. Hodkinson et al.

JOURNAL OF ENDOCRINOLOGY (2009)

Add to Collection

Review Virology

Viruses and thyroiditis: an update

Rachel Desailloud et al.

VIROLOGY JOURNAL (2009)

Add to Collection

Article Endocrinology & Metabolism

Identification of molecular mechanisms related to nonthyroidal illness syndrome in skeletal muscle and adipose tissue from patients with septic shock

Alfonso Rodriguez-Perez et al.

CLINICAL ENDOCRINOLOGY (2008)

Add to Collection

Article Immunology

Activation of NF-kappa B in lymphocytes and increase in serum immunoglobulin in hyperthyroidism: Possible role of oxidative stress

D. N. Nandakumar et al.

IMMUNOBIOLOGY (2008)

Add to Collection

Review Virology

Pathogenetic mechanisms of severe acute respiratory syndrome

Yong Guo et al.

VIRUS RESEARCH (2008)

Add to Collection

Article Endocrinology & Metabolism

The type II iodothyronine deiodinase is up-regulated in skeletal muscle during prolonged critical illness

Liese Mebis et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Add to Collection

Article Pathology

Pathology of the thyroid in severe acute respiratory syndrome

Lan Wei et al.

HUMAN PATHOLOGY (2007)

Add to Collection

Article Endocrinology & Metabolism

Chronic local inflammation in mice results in decreased TRH and type 3 deiodinase mRNA expression in the hypothalamic paraventricular nucleus independently of diminished food intake

A. Boelen et al.

JOURNAL OF ENDOCRINOLOGY (2006)

Add to Collection

Article Endocrinology & Metabolism

Expression of TPO and ThOXs in human thyrocytes is downregulated by IL-1α/IFN-γ, an effect partially mediated by nitric oxide

Anne-Catherine Gerard et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Add to Collection

Article Endocrinology & Metabolism

Integrative study of hypothalamus-pituitary-thyroid-immune system interaction: thyroid hormone-mediated modulation of lymphocyte activity through the protein kinase C signaling pathway

AJ Klecha et al.

JOURNAL OF ENDOCRINOLOGY (2006)

Add to Collection

Article Medicine, Research & Experimental

Thyroid hormone regulation of cell migration and oxidative metabolism in polymorphonuclear leukocytes: Clinical evidence in thyroidectomized subjects on thyroxine replacement therapy

F Marino et al.

LIFE SCIENCES (2006)

Add to Collection

Article Endocrinology & Metabolism

Tissue thyroid hormone levels in critical illness

RP Peeters et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Add to Collection

Article Medicine, Research & Experimental

Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans

AL Maia et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Add to Collection

Article Endocrinology & Metabolism

Hypocortisolism in survivors of severe acute respiratory syndrome (SARS)

MKS Leow et al.

CLINICAL ENDOCRINOLOGY (2005)

Add to Collection

Article Endocrinology & Metabolism

Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice

A Boelen et al.

JOURNAL OF ENDOCRINOLOGY (2004)

Add to Collection

Article Immunology

Effect of the period of treatment with a single dose of propylthiouracil on the antibody response in rats

CG Duarte et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2003)

Add to Collection

Article Endocrinology & Metabolism

Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients

RP Peeters et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)

Add to Collection

Article Medicine, General & Internal

Association between increased levels of reverse triiodothyronine and mortality after acute myocardial infarction

L Friberg et al.

AMERICAN JOURNAL OF MEDICINE (2001)

Add to Collection

Article Immunology

Experimental evidence pointing to the bidirectional interaction between the immune system and the thyroid axis

AJ Klecha et al.

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY (2000)

Add to Collection

COVID-19 and thyroid function: What do we know so far?

Related references

Export Citation

Share Paper