Journal
FRONTIERS IN ENDOCRINOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2022.1050709
Keywords
liver-gut axis; intestinal microorganisms; traditional Chinese medicine; NAFLD; target
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Funding
- Natural Science Foundation of Changsha
- Changsha Science and Technology Bureau
- [kq2202061]
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This review assessed the modulation of the liver-gut microbiota axis as a therapeutic approach to non-alcoholic fatty liver disease (NAFLD) using traditional Chinese medicine (TCM), and explored its application in other therapeutic avenues.
Non-alcoholic fatty liver disease (NAFLD) occurs when fat accumulates in the liver even without excessive alcohol intake. Among the current therapeutic approaches for NAFLD, lifestyle modification with dietary changes and regular exercise is the mainstay treatment. With the rise of intestinal microecology, regulation of the liver-gut axis can be an effective treatment for NAFLD. This review aimed to assess the modulation of the liver-gut microbiota axis with traditional Chinese medicine (TCM) as a therapeutic approach to NAFLD and further explored its application in the newly discovered therapeutic avenues beyond NAFLD treatment.
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