Biological characteristics of γδT cells and application in tumor immunotherapy

Human gamma delta T cells are a special immune cell type which exist in small quantities in the body, do not require processing and presentation for antigen recognition, and have non-major histocompatibility complex (MHC)-restricted immune response. They play an important role in the body's anti-tumor, anti-infection, immune regulation, immune surveillance and maintenance of immune tolerance. This article reviews the generation and development of human gamma delta T cells, genetic characteristics, classification, recognition and role of antigens, and research progress in tumor immunotherapy.

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This article reviews the generation and development of human gamma delta T cells, their genetic characteristics, classification, antigen recognition and role, as well as research progress in tumor immunotherapy.