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Progress of photoacoustic imaging combined with targeted photoacoustic contrast agents in tumor molecular imaging

Journal

FRONTIERS IN CHEMISTRY
Volume 10, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fchem.2022.1077937

Keywords

photoacoustic imaging; targeted contrast agent; molecular imaging; tumor microenvironment; diagnosis

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Molecular imaging is a valuable technology in oncology for precise diagnosis and treatment. Photoacoustic imaging, a novel imaging technique, utilizes the photoacoustic effect to obtain internal tissue information. Currently, photoacoustic imaging combined with targeted photoacoustic contrast agents is widely used in tumor molecular imaging research.
Molecular imaging visualizes, characterizes, and measures biological processes at the molecular and cellular level. In oncology, molecular imaging is an important technology to guide integrated and precise diagnosis and treatment. Photoacoustic imaging is mainly divided into three categories: photoacoustic microscopy, photoacoustic tomography and photoacoustic endoscopy. Different from traditional imaging technology, which uses the physical properties of tissues to detect and identify diseases, photoacoustic imaging uses the photoacoustic effect to obtain the internal information of tissues. During imaging, lasers excite either endogenous or exogenous photoacoustic contrast agents, which then send out ultrasonic waves. Currently, photoacoustic imaging in conjunction with targeted photoacoustic contrast agents is frequently employed in the research of tumor molecular imaging. In this study, we will examine the latest advancements in photoacoustic imaging technology and targeted photoacoustic contrast agents, as well as the developments in tumor molecular imaging research.

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