Related references
Note: Only part of the references are listed.SARS-CoV-2 infections in children: Understanding diverse outcomes
Petter Brodin
IMMUNITY (2022)
Temporal signaling, population control, and information processing through chromatin-mediated gene regulation
Adi Mukund et al.
JOURNAL OF THEORETICAL BIOLOGY (2022)
Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses
Piotr Topolewski et al.
SCIENCE SIGNALING (2022)
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF
Stefanie Dichtl et al.
LIFE SCIENCE ALLIANCE (2022)
Functional Hallmarks of Healthy Macrophage Responses: Their Regulatory Basis and Disease Relevance
Katherine M. Sheu et al.
ANNUAL REVIEW OF IMMUNOLOGY (2022)
A common framework of monocyte-derived macrophage activation
David E. Sanin et al.
SCIENCE IMMUNOLOGY (2022)
Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes
Bowen Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2022)
Statistics or biology: the zero-inflation controversy about scRNA-seq data
Ruochen Jiang et al.
GENOME BIOLOGY (2022)
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging
Denis A. Mogilenko et al.
IMMUNITY (2021)
Untuned antiviral immunity in COVID-19 revealed by temporal type I/III interferon patterns and flu comparison
Ioanna-Evdokia Galani et al.
NATURE IMMUNOLOGY (2021)
Immune determinants of COVID-19 disease presentation and severity
Petter Brodin
NATURE MEDICINE (2021)
Co-stimulation with opposing macrophage polarization cues leads to orthogonal secretion programs in individual cells
Andres R. Munoz-Rojas et al.
NATURE COMMUNICATIONS (2021)
Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19
Can Liu et al.
CELL (2021)
Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing
Yael C. Cohen et al.
NATURE MEDICINE (2021)
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia
Yu-Ling Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Quantifying information accumulation encoded in the dynamics of biochemical signaling
Ying Tang et al.
NATURE COMMUNICATIONS (2021)
Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses
Adewunmi Adelaja et al.
IMMUNITY (2021)
Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
Jenn-Haung Lai et al.
ISCIENCE (2021)
Stimulus-specific responses in innate immunity: Multilayered regulatory circuits
Stefanie Luecke et al.
IMMUNITY (2021)
NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages
Quen J. Chen et al.
SCIENCE (2021)
Identifying the combinatorial control of signal-dependent transcription factors
Ning Wang et al.
PLOS COMPUTATIONAL BIOLOGY (2021)
MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation
Gilberto Betancor et al.
NATURE MICROBIOLOGY (2021)
Mammalian gene expression variability is explained by underlying cell state
Robert Foreman et al.
MOLECULAR SYSTEMS BIOLOGY (2020)
Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis
Nobuyuki Kakiuchi et al.
NATURE (2020)
Macrophages employ quorum licensing to regulate collective activation
Joseph J. Muldoon et al.
NATURE COMMUNICATIONS (2020)
The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?
Julia L. McKechnie et al.
CELL HOST & MICROBE (2020)
Cytokine release syndrome in severe COVID-19
John B. Moore et al.
SCIENCE (2020)
A Targeted Multi-omic Analysis Approach Measures Protein Expression and Low-Abundance Transcripts on the Single-Cell Level
Florian Mair et al.
CELL REPORTS (2020)
Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response
Kaitlyn A. Sun et al.
ELIFE (2020)
Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity
Alexander E. Davies et al.
CELL SYSTEMS (2020)
A dynamic COVID-19 immune signature includes associations with poor prognosis
Adam G. Laing et al.
NATURE MEDICINE (2020)
Information transmission from NFkB signaling dynamics to gene expression
Alok Maity et al.
PLOS COMPUTATIONAL BIOLOGY (2020)
Normalizing single-cell RNA sequencing data with internal spike-in-like genes
Li Lin et al.
NAR GENOMICS AND BIOINFORMATICS (2020)
Considering how biological sex impacts immune responses and COVID-19 outcomes
Eileen P. Scully et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
Luca Cassetta et al.
CANCER CELL (2019)
Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions
Quen Cheng et al.
SCIENTIFIC REPORTS (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation
Kyuho Kang et al.
NATURE COMMUNICATIONS (2019)
Information-theoretic analysis of multivariate single-cell signaling responses
Tomasz Jetka et al.
PLOS COMPUTATIONAL BIOLOGY (2019)
Circulating T cell-monocyte complexes are markers of immune perturbations
Julie G. Burel et al.
ELIFE (2019)
An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms
Simon Mitchell et al.
FRONTIERS IN IMMUNOLOGY (2019)
Skewed macrophage polarization in aging skeletal muscle
Chang-Yi Cui et al.
AGING CELL (2019)
Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases
Theodore S. Kapellos et al.
FRONTIERS IN IMMUNOLOGY (2019)
Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?
Adriaan A. van Beek et al.
TRENDS IN IMMUNOLOGY (2019)
The Limited Information Capacity of Cross-Reactive Sensors Drives the Evolutionary Expansion of Signaling
Micha Komorowski et al.
CELL SYSTEMS (2019)
Emerging Functions of Human IFIT Proteins in Cancer
Vijaya Kumar Pidugu et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2019)
The translation of non-canonical open reading frames controls mucosal immunity
Ruaidhri Jackson et al.
NATURE (2018)
An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling
Tomasz Jetka et al.
NATURE COMMUNICATIONS (2018)
Immune Functional Assays, From Custom to Standardized Tests for Precision Medicine
Chloe Albert-Vega et al.
FRONTIERS IN IMMUNOLOGY (2018)
Fundamental trade-offs between information flow in single cells and cellular populations
Ryan Suderman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Iterative Modeling Reveals Evidence of Sequential Transcriptional Control Mechanisms
Christine S. Cheng et al.
CELL SYSTEMS (2017)
Systematic Analysis of the Determinants of Gene Expression Noise in Embryonic Stem Cells
Andre J. Faure et al.
CELL SYSTEMS (2017)
Monocyte inflammatory profile is specific for individuals and associated with altered blood lipid levels
Vyoma K. Patel et al.
ATHEROSCLEROSIS (2017)
Regulation of PHLDA1 Expression by JAK2-ERK1/2-STAT3 Signaling Pathway
Ji Hyo Lyu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2016)
A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation
Ann-Jay Tong et al.
CELL (2016)
New insights into the multidimensional concept of macrophage ontogeny, activation and function
Florent Ginhoux et al.
NATURE IMMUNOLOGY (2016)
Innate cell communication kick-starts pathogen-specific immunity
Amariliz Rivera et al.
NATURE IMMUNOLOGY (2016)
Dynamics of epigenetic regulation at the single-cell level
Lacramioara Bintu et al.
SCIENCE (2016)
SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis
Maksim V. Baranov et al.
CELL REPORTS (2016)
Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses
Alejandra Urrutia et al.
CELL REPORTS (2016)
Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady- State Microbe Sensing from Anti-pathogen Inflammatory Responses
Rachel A. Gottschalk et al.
CELL SYSTEMS (2016)
Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation
Zhang Cheng et al.
SCIENCE SIGNALING (2015)
Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression
Jong Kyoung Kim et al.
NATURE COMMUNICATIONS (2015)
Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation
Zhang Cheng et al.
SCIENCE SIGNALING (2015)
Migration of Myeloid Cells during Inflammation Is Differentially Regulated by the Cell Surface Receptors Slamf1 and Slamf8
Guoxing Wang et al.
PLOS ONE (2015)
Noise and Information Transmission in Promoters with Multiple Internal States
Georg Rieckh et al.
BIOPHYSICAL JOURNAL (2014)
Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages
Yasutaka Okabe et al.
CELL (2014)
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
Yonit Lavin et al.
CELL (2014)
Network dynamics determine the autocrine and paracrine signaling functions of TNF
Andrew B. Caldwell et al.
GENES & DEVELOPMENT (2014)
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J. Murray et al.
IMMUNITY (2014)
Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
Jia Xue et al.
IMMUNITY (2014)
Fold Change of Nuclear NF-κB Determines TNF-Induced Transcription in Single Cells
Robin E. C. Lee et al.
MOLECULAR CELL (2014)
Nucleosomal promoter variation generates gene expression noise
Christopher R. Brown et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Accurate information transmission through dynamic biochemical signaling networks
Jangir Selimkhanov et al.
SCIENCE (2014)
Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjogren's Syndrome-like Autoimmune Disease
Atsushi Okuma et al.
IMMUNITY (2013)
Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species
Yingke Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Protective Roles of Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3) in Dengue Virus Infection of Human Lung Epithelial Cells
Yu-Lin Hsu et al.
PLOS ONE (2013)
Robustness and Compensation of Information Transmission of Signaling Pathways
Shinsuke Uda et al.
SCIENCE (2013)
Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression
Christopher R. Brown et al.
PLOS BIOLOGY (2013)
Caveolin-1 Plays a Critical Role in the Differentiation of Monocytes into Macrophages
Yi Fu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Monocytes as a diagnostic marker of cardiovascular diseases
Alexei Gratchev et al.
IMMUNOBIOLOGY (2012)
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
Guangchuang Yu et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)
How Information Theory Handles Cell Signaling and Uncertainty
Matthew D. Brennan et al.
SCIENCE (2012)
C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients
Andrew Conway Morris et al.
BLOOD (2011)
Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
Jonathan S. Boomer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)
Information transmission in genetic regulatory networks: a review
Gasper Tkacik et al.
JOURNAL OF PHYSICS-CONDENSED MATTER (2011)
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils
Stephen J. Galli et al.
NATURE IMMUNOLOGY (2011)
Microbial manipulation of receptor crosstalk in innate immunity
George Hajishengallis et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Protective and pathogenic functions of macrophage subsets
Peter J. Murray et al.
NATURE REVIEWS IMMUNOLOGY (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Understanding the temporal codes of intra-cellular signals
Marcelo Behar et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)
Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype
Susan K. Mathai et al.
LABORATORY INVESTIGATION (2010)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay
Kazufumi Matsushita et al.
NATURE (2009)
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production
Mikyoung Chang et al.
NATURE IMMUNOLOGY (2009)
Tensor Decompositions and Applications
Tamara G. Kolda et al.
SIAM REVIEW (2009)
Information capacity of genetic regulatory elements
Gasper Tkacik et al.
PHYSICAL REVIEW E (2008)
Information flow and optimization in transcriptional regulation
Gasper Tkacik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria
Yunjian Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Intrinsic and extrinsic contributions to stochasticity in gene expression
PS Swain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Stochastic gene expression in a single cell
MB Elowitz et al.
SCIENCE (2002)
Human macrophage activation programs induced by bacterial pathogens
GJ Nau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains -: Elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-α and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice
DG Alleva et al.
DIABETES (2000)