Timing of Active Left Ventricular Unloading in Patients on Venoarterial Extracorporeal Membrane Oxygenation Therapy

Review Cardiac & Cardiovascular Systems

Left Ventricular Unloading Before Percutaneous Coronary Intervention is Associated With Improved Survival in Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock: A Systematic Review and Meta-Analysis

Satoshi Miyashita et al.

Summary: This study retrospectively analyzed the impact of left ventricular unloading on survival rates in AMI-CS patients and found that pre-PCI Impella placement was associated with better survival.

CARDIOVASCULAR REVASCULARIZATION MEDICINE (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Mechanical Left Ventricular Unloading in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation

E. Wilson Grandin et al.

Summary: Among adults receiving VA-ECMO, mechanical unloading (MU) with intra-aortic balloon pump (IABP) or percutaneous ventricular assist device (pVAD) was associated with lower in-hospital mortality and increased complications. Compared to pVAD, MU with IABP had similar mortality and lower complication rates.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

Add to Collection

Review Medicine, General & Internal

Cardiogenic Shock After Acute Myocardial Infarction A Review

Marc D. Samsky et al.

Summary: Cardiogenic shock affects 40,000 to 50,000 people in the US annually and is a leading cause of in-hospital mortality post acute myocardial infarction. Immediate revascularization of the infarct-related coronary artery is the primary treatment recommended, supported by clinical trials. Despite lack of definitive evidence, mechanical circulatory support devices are frequently utilized in managing cardiogenic shock.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Temporal trends in incidence, causes, use of mechanical circulatory support and mortality in cardiogenic shock

Benedikt Schrage et al.

Summary: This nationwide study in Germany from 2005 to 2017 revealed an increasing incidence of cardiogenic shock, with acute myocardial infarction being the most common cause initially but decreasing in proportion over time. Although there was a shift towards using novel mechanical circulatory support devices, mortality remained high for cardiogenic shock despite these advancements.

ESC HEART FAILURE (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Extracorporeal life support in patients with acute myocardial infarction complicated by cardiogenic shock-Design and rationale of the ECLS-SHOCK trial

Holger Thiele et al.

Summary: The ECLS-SHOCK trial is a 420-patient controlled, international, multicenter, randomized, open-label trial aiming to investigate the efficacy and safety of ECLS in addition to early revascularization in acute myocardial infarction complicated by cardiogenic shock. Patients will be randomized to either ECLS plus early revascularization or no-ECLS treatment arms, with 30-day mortality as the primary efficacy endpoint.

AMERICAN HEART JOURNAL (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Veno-arterial extracorporeal membrane oxygenation (ECMO) in patients with cardiogenic shock: rationale and design of the-label EURO SHOCK trial

Amerjeet S. Banning et al.

Summary: The EURO SHOCK trial aims to investigate whether early initiation of VA-ECMO in patients with ACS-CGS after PCI can improve mortality and morbidity outcomes.

EUROINTERVENTION (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems