Journal
JOURNAL OF PAIN RESEARCH
Volume 15, Issue -, Pages 3859-3867Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/JPR.S386565
Keywords
race; pain; vitamin D; disparities
Categories
Funding
- University of Alabama at Birmingham Health Services Research Training Program [T32HS013852]
- National Institute on Minority Health and Health Disparities of the National Institutes of Health [R01MD010441]
- National Institutes of Health Center for Advancing Translational Sciences [UL1TR001417]
Ask authors/readers for more resources
The findings suggest that Vitamin D deficiency may be associated with increased pain severity in patients with chronic low back pain (cLBP), especially among Non-Hispanic Black individuals.
Introduction: Considerable evidence suggests that there are significant ethnic/racial differences in the experience of pain among individuals suffering from chronic musculoskeletal conditions. Additionally, low levels of vitamin D have been associated with pain severity. Further, vitamin D deficiency is more prevalent in Non-Hispanic Black (NHB) individuals compared to Non-Hispanic Whites (NHW).Objective: The aim of this study was to investigate the associations among race, pain severity, and serum levels of vitamin D in a sample of patients with chronic low back pain (cLBP).Methods: All study participants (n = 155) self-identified their race/ethnicity as either NHB or NHW. Blood samples were collected to assess circulating levels of serum 25-hydroxy vitamin D. Vitamin D levels were categorized as optimal (>= 20 ng/mL), insufficient (12- 19 ng/mL) or deficient (<12 ng/mL). Participants then self-reported their pain severity using the Brief Pain Inventory - Short Form.Results: Results showed that a greater proportion of NHB versus NHW participants were categorized as Vitamin D deficient (chi 2 (2, N = 155) = 16.79, p < 0.001). An analysis of covariance (ANCOVA) revealed that NHBs reported significantly greater pain severity relative to NHWs (F(1150) = 6.45) p = 0.012. Further, self-reported pain severity significantly differed according to Vitamin D clinical categories (F(2150) = 4.19, p = 0.013). Participants with deficient vitamin D reported significantly greater pain severity in comparison to participants with optimal vitamin D (F(1101) = 7.28, p = 0.008).Conclusion: The findings suggest that Vitamin D deficiency may be linked to greater pain severity in a sample of individuals with cLBP, especially for those who identify as NHB.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available