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Asthma Management in Children

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ELSEVIER
DOI: 10.1016/j.jaip.2022.10.031

Keywords

Ohio; Asthma inception; Asthma management; Asthma phenotypes; Asthma risk factors; Childhood asthma; Preschool asthma; School age asthma; Severe asthma; Social determinants

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Asthma is a common and complex disease, particularly in children, characterized by reversible airflow obstruction. The phenotypic differences in children with asthma may influence comorbidities and treatment choices. Prenatal factors such as maternal diet and microbiome, as well as postnatal microbial exposures and colonization, contribute to the risk of asthma and allergic diseases.
Asthma is a common, complex heterogeneous disease often beginning in early life and is characterized by reversible airflow obstruction. The phenotypic differences that exist in children with asthma may impact underlying comorbid conditions and pharmacologic treatment choices. Prenatal factors for increased risk of asthma could include maternal diet and the maternal microbiome. Evidence also suggests that postnatal microbial exposures and colonization contribute to the risk of allergic diseases and asthma. After confirming the diagnosis, asthma management in children centers on 3 broad areas: pharmacologic treatment, treatment of underlying comorbidities, and education of the patient and caregivers on the importance of adherence and device technique. Moreover, social determinants of health significantly impact on symptom burden and treatment response. (c) 2022 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:9-18)

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