Journal
FRONTIERS IN NEUROLOGY
Volume 14, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2023.1082060
Keywords
atypical parkinsonism; magnetic resonance parkinsonism index; neuromelanin MRI; diffusion MRI; susceptibility-weighted imaging; quantitative susceptibility mapping
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Accurate and timely diagnosis of atypical parkinsonian syndromes (APS) remains a challenge. However, recent advances in MRI technology have introduced promising imaging modalities to aid in the diagnosis of APS.
Accurate and timely diagnosis of atypical parkinsonian syndromes (APS) remains a challenge. Especially early in the disease course, the clinical manifestations of the APS overlap with each other and with those of idiopathic Parkinson's disease (PD). Recent advances in magnetic resonance imaging (MRI) technology have introduced promising imaging modalities to aid in the diagnosis of APS. Some of these MRI modalities are also included in the updated diagnostic criteria of APS. Importantly, MRI is safe for repeated use and more affordable and accessible compared to nuclear imaging. These advantages make MRI tools more appealing for diagnostic purposes. As the MRI field continues to advance, the diagnostic use of these techniques in APS, alone or in combination, are expected to become commonplace in clinical practice.
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