Journal
FRONTIERS IN IMMUNOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.1053914
Keywords
nocardiosis; antibiotic susceptibility; pathogen identification; metagenomic next-generation sequencing; whole genome sequencing; case report
Categories
Funding
- Double First-Class and High-level University Discipline Collaborative Innovation Team Project of Guangzhou University of Chinese Medicine
- Special project for inheriting classics of clinical Chinese medicine [2021XK16]
- Guangzhou University of Chinese Medicine
- [A1-2601-22-429-002Z02]
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Infection of Nocardia gipuzkoensis is a relatively uncommon form of pulmonary nocardiosis, usually occurring in patients with immune deficiency. We report a case of a 23-year-old female with a 10-year history of cough and sputum production, diagnosed with bronchiectasis. The infection was identified using metagenomic next-generation sequencing and whole genome sequencing, and was controlled with appropriate medication.
The infection of Nocardia gipuzkoensis is a relatively uncommon form of pulmonary nocardiosis seen in clinical patients. In general, nocardiosis tends to occur in patients with immune deficiency. Here, we report a 23-year-old female who was admitted to the hospital due to cough and sputum production over 10 years, diagnosed with bronchiectasis. The N. gipuzkoensis infection was identified by metagenomic next-generation sequencing and whole genome sequencing. Imipenem/cilastatin and compound sulfamethoxazole tablets were used to control the infection and the pulmonary inflammation subsided gradually.
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