Related references
Note: Only part of the references are listed.Mechanisms of SARS-CoV-2 entry into cells
Cody B. Jackson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2022)
Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
Yimin Huang et al.
CELL REPORTS (2022)
Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model
Christopher Kaufer et al.
EBIOMEDICINE (2022)
SARS-CoV-2 Infection of Microglia Elicits Proinflammatory Activation and Apoptotic Cell Death
Gi Uk Jeong et al.
MICROBIOLOGY SPECTRUM (2022)
What SARS-CoV-2 does to our brains
Tom Aschman et al.
IMMUNITY (2022)
Toll-like receptor (TLRs) agonists and antagonists for COVID-19 treatments
Zhi-Mei Liu et al.
FRONTIERS IN PHARMACOLOGY (2022)
Regulation of the nucleic acid-sensing Toll-like receptors
Nicholas A. Lind et al.
NATURE REVIEWS IMMUNOLOGY (2022)
Phase 1 study in healthy participants of the safety, pharmacokinetics, and pharmacodynamics of enpatoran (M5049), a dual antagonist of toll-like receptors 7 and 8
Andreas Port et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2021)
The coding capacity of SARS-CoV-2
Yaara Finkel et al.
NATURE (2021)
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis
Armin Bayati et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Neuroinvasion of SARS-CoV-2 in human and mouse brain
Eric Song et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
Jenny Meinhardt et al.
NATURE NEUROSCIENCE (2021)
Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2
Tianling Ou et al.
PLOS PATHOGENS (2021)
Intrathecal inflammatory responses in the absence of SARS-CoV-2 nucleic acid in the CSF of COVID-19 hospitalized patients
Erica Normandin et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2021)
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions
Marius Schwabenland et al.
IMMUNITY (2021)
TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages
Natalya Odoardi et al.
JOURNAL OF INNATE IMMUNITY (2021)
SARS-CoV-2 targets MAVS for immune evasion
Alessia Zotta et al.
NATURE CELL BIOLOGY (2021)
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-I
Yiwen Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands
Martin Raden et al.
RNA BIOLOGY (2021)
X-linked recessive TLR7 deficiency in ∼1% of men under 60 years old with life-threatening COVID-19
Takaki Asano et al.
SCIENCE IMMUNOLOGY (2021)
SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8
Valentina Salvi et al.
JCI INSIGHT (2021)
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang et al.
LANCET (2020)
Single-nucleus RNA-seq identifies Huntington disease astrocyte states
Osama Al-Dalahmah et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2020)
Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing
Thomas Wallach et al.
CELLS (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
CELL (2020)
Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2
Thomas Ostendorf et al.
IMMUNITY (2020)
A first case of meningitis/encephalitis associated with SARS-Coronavirus-2
Takeshi Moriguchi et al.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)
Characteristics of ischaemic stroke associated with COVID-19
Rahma Beyrouti et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2020)
Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
Ling Mao et al.
JAMA NEUROLOGY (2020)
Bioinformatic analysis and identi fication of single -stranded RNA sequences recognized by TLR7/8 in the SARS-CoV-2, SARS-CoV, and MERS-CoV genomes
Mario Adan Moreno-Eutimio et al.
MICROBES AND INFECTION (2020)
Neurologic Features in Severe SARS-CoV-2 Infection
Julie Helms et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
COVID-19: Immunology and treatment options
Susanna Felsenstein et al.
CLINICAL IMMUNOLOGY (2020)
RNase T2 in Inflammation and Cancer: Immunological and Biological Views
Lei Wu et al.
FRONTIERS IN IMMUNOLOGY (2020)
Presence of Genetic Variants Among Young Men With Severe COVID-19
Caspar I. van der Made et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)
Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19
Athina Angelopoulou et al.
ENVIRONMENTAL RESEARCH (2020)
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Qian Zhang et al.
SCIENCE (2020)
Structural analysis reveals TLR7 dynamics underlying antagonism
Shingo Tojo et al.
NATURE COMMUNICATIONS (2020)
A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors
Manvendra Singh et al.
CELL REPORTS (2020)
β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway
Sourish Ghosh et al.
CELL (2020)
Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study
Bernadette Schurink et al.
LANCET MICROBE (2020)
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Miriam Merad et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors
Paul Dembny et al.
JCI INSIGHT (2020)
TLR8 Is a Sensor of RNase T2 Degradation Products
Wilhelm Greulich et al.
CELL (2019)
INTARNAHELIX-composing RNA-RNA interactions from stable inter-molecular helices boosts bacterial sRNA target prediction
Rick Gelhausen et al.
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY (2019)
Wild-type human coronaviruses prefer cell-surface TMPRSS2 to endosomal cathepsins for cell entry
Kazuya Shirato et al.
VIROLOGY (2018)
Development and validation of a simplified method to generate human microglia from pluripotent stem cells
Amanda McQuade et al.
MOLECULAR NEURODEGENERATION (2018)
Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands
Zhikuan Zhang et al.
CELL REPORTS (2018)
Microglia and macrophages in brain homeostasis and disease
Qingyun Li et al.
NATURE REVIEWS IMMUNOLOGY (2018)
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
Edsel M. Abud et al.
NEURON (2017)
IntaRNA 2.0: enhanced and customizable prediction of RNA-RNA interactions
Martin Mann et al.
NUCLEIC ACIDS RESEARCH (2017)
Guanosine and its modified derivatives are endogenous ligands for TLR7
Takuma Shibata et al.
INTERNATIONAL IMMUNOLOGY (2016)
Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
Zhikuan Zhang et al.
IMMUNITY (2016)
Toll-like receptor 8 senses degradation products of single-stranded RNA
Hiromi Tanji et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Toll-like receptor 8 senses degradation products of single-stranded RNA
Hiromi Tanji et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Extraordinary GU-rich single-strand RNA identified from SARS coronavirus contributes an excessive innate immune response
Yan Li et al.
MICROBES AND INFECTION (2013)
1,25-Dihydroxyvitamin D3 Suppresses TLR8 Expression and TLR8-Mediated Inflammatory Responses in Monocytes In Vitro and Experimental Autoimmune Encephalomyelitis In Vivo
Bo Li et al.
PLOS ONE (2013)
Extracellularly Delivered Single-Stranded Viral RNA Causes Neurodegeneration Dependent on TLR7
Sabrina M. Lehmann et al.
JOURNAL OF IMMUNOLOGY (2012)
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
Sabrina M. Lehmann et al.
NATURE NEUROSCIENCE (2012)
ViennaRNA Package 2.0
Ronny Lorenz et al.
ALGORITHMS FOR MOLECULAR BIOLOGY (2011)
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
Taro Kawai et al.
NATURE IMMUNOLOGY (2010)
TLR8-dependent TNF-α overexpression in Fanconi anemia group C cells
Scott M. Vanderwerf et al.
BLOOD (2009)
TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages
Michael P. Gantier et al.
JOURNAL OF IMMUNOLOGY (2008)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
SS Diebold et al.
SCIENCE (2004)
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
F Heil et al.
SCIENCE (2004)
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
JK Olson et al.
JOURNAL OF IMMUNOLOGY (2004)
Broad expression of Toll-like receptors in the human central nervous system
M Bsibsi et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
M Jurk et al.
NATURE IMMUNOLOGY (2002)
The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS
S Lehnardt et al.
JOURNAL OF NEUROSCIENCE (2002)