Ensemble Machine Learning for Monkeypox Transmission Time Series Forecasting

Article Immunology

Understanding Spatiotemporal Human Mobility Patterns for Malaria Control Using a Multiagent Mobility Simulation Model

Yao Li et al.

Summary: A multiagent mobility simulation model was built to simulate the movements of villagers in two townships in Myanmar. The study identified different mobility patterns and malaria exposure risks among different occupation groups.

CLINICAL INFECTIOUS DISEASES (2023)

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Article Public, Environmental & Occupational Health

Polymerase Chain Reaction-Based Malaria Diagnosis Can Be Increasingly Adopted during Current Phase of Malaria Elimination in India

Manju Rahi et al.

Summary: Despite progress in malaria control in India and other countries, submicroscopic infections remain a hidden reservoir that current diagnostic tools are unable to detect. Introducing more sensitive molecular tools like PCR for routine diagnosis is crucial to detect and treat these hidden burdens of malaria, especially in low-endemic settings like India. By utilizing facilities established for COVID-19 diagnosis, PCR could be easily integrated into routine national malaria control programs to enhance surveillance and control efforts.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2022)

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Editorial Material Infectious Diseases

Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529)-highlights Africa's research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts

Eskild Petersen et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

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News Item Medicine, General & Internal

Vaccine Development Is Charting a New Path in Malaria Control

Bridget M. Kuehn

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Infectious Diseases

Estimating the effect of vaccination on antimicrobial-resistant typhoid fever in 73 countries supported by Gavi: a mathematical modelling study

Ruthie Birger et al.

Summary: This study used mathematical models and meta-analyses to estimate the burden of antimicrobial-resistant typhoid fever in 73 lower-income countries, predicting that the introduction of TCV immunization can significantly reduce the incidence and mortality of antimicrobial-resistant typhoid fever.

LANCET INFECTIOUS DISEASES (2022)

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Article Biochemistry & Molecular Biology

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year

Clare Smith et al.

Summary: A clinical review of all pediatric deaths in England from March 2020 to February 2021 attributes 25 deaths to SARS-CoV-2 infection and identifies risk factors to guide interventions. These results are important for guiding decisions on shielding and vaccinating children, with factors like age, ethnicity, and comorbidities potentially influencing mortality rates related to SARS-CoV-2.

NATURE MEDICINE (2022)

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Article Public, Environmental & Occupational Health

Global research activity on mathematical modeling of transmission and control of 23 selected infectious disease outbreak

Waleed M. Sweileh

Summary: This study analyzed global research activity on mathematical modeling of transmission and control of infectious diseases and made several findings: COVID-19 had a strong impact on the number of publications in the field; research in the field was published in a wide range of journals, mainly those in the field of infectious diseases and mathematical sciences; articles in this field were mainly published by scholars from the United States and the United Kingdom; international research collaboration was poor; HIV/AIDS, coronavirus disease, influenza, and malaria were the most frequently researched diseases; recently published articles on COVID-19 received the highest number of citations; researchers from the Eastern Mediterranean and South-East Asian regions made the least contribution to the field.

GLOBALIZATION AND HEALTH (2022)

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Article Tropical Medicine

The changing epidemiology of human monkeypox—A potential threat? A systematic review

Eveline M. Bunge et al.

PLoS Neglected Tropical Diseases (2022)

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Article Microbiology

The COMBAT-TB Workbench: Making Powerful Mycobacterium tuberculosis Bioinformatics Accessible

Peter van Heusden et al.

mSphere (2022)

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Article Infectious Diseases

Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022

Andrea Antinori et al.

Summary: Since May 2022, there has been an ongoing monkeypox outbreak in non-endemic countries. Four cases in young adult men in Italy, who engaged in condomless sexual intercourse, were reported. The patients are in good clinical condition and do not require specific antiviral drugs. Monkeypox viral DNA was detected in seminal fluid samples. The possibility of sexual transmission of monkeypox virus needs to be investigated.

EUROSURVEILLANCE (2022)

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Article Infectious Diseases

Using Bayesian state-space models to understand the population dynamics of the dominant malaria vector, Anopheles funestus in rural Tanzania

Halfan S. Ngowo et al.

Summary: This study developed a model that accurately reconstructed the population dynamics and ecology of An. funestus mosquitoes and examined their response to interventions. The results showed that seasonal variation and density dependence had a relatively minor impact on the stability and responsiveness of An. funestus populations.

MALARIA JOURNAL (2022)

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News Item Multidisciplinary Sciences

MONKEYPOX GOES GLOBAL: WHY SCIENTISTS ARE ON ALERT

Max Kozlov

NATURE (2022)

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Letter Biochemistry & Molecular Biology

Dynamical malaria modeling as a tool for bold policy-making

Branwen Nia Owen et al.

NATURE MEDICINE (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Cardiac MRI of Hereditary Cardiomyopathy

Shaimaa A. Fadl et al.

Summary: Cardiac MRI plays a crucial role in evaluating patients with hereditary cardiomyopathy by assessing various tissue properties. Different MRI techniques can differentiate between different types of hereditary cardiomyopathy and aid in diagnosis and treatment.

RADIOGRAPHICS (2022)

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Article Multidisciplinary Sciences

Monitoring IgG against Mycobacterium tuberculosis proteins in an Asian elephant cured of tuberculosis that developed from long-term latency

Satoshi Ishikawa et al.

Summary: Tuberculosis is fatal in elephants, and protecting elephants from the disease is crucial for conservation and preventing transmission to humans. A study on elephant TB serum samples found that proteins ESAT6/CFP10 and Ag85B play key roles in infection and disease development.

SCIENTIFIC REPORTS (2022)

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Article Infectious Diseases

Emergence of multi-drug-resistant Mycobacterium tuberculosis in Niger: A snapshot based on whole-genome sequencing

Zelika Harouna Hamidou et al.

Summary: Tuberculosis is a major public health problem in Niger, and this study provides unprecedented data on the dynamics of tuberculosis transmission and drug resistance in the country. Whole genome sequencing revealed different lineages and sub-lineages of Mycobacterium tuberculosis, with the Euro-American L4 lineage being the most predominant. The majority of isolates showed resistance to multiple drugs, highlighting the urgent need for epidemiological surveillance and effective treatment strategies.

PLOS NEGLECTED TROPICAL DISEASES (2022)

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Article Microbiology

Bioinformatic Mining and Structure-Activity Profiling of Baeyer-Villiger Monooxygenases from Mycobacterium tuberculosis

Nicolas Tomas et al.

Summary: Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a leading cause of global mortality and drug resistance is a rising problem in TB treatment, necessitating the development of innovative anti-TB drugs. Baeyer-Villiger monooxygenases (BVMOs) play a crucial role in the bioactivation of many anti-TB drugs, but their structural and functional features remain largely unknown. In this study, a comprehensive bioinformatic analysis confirmed the presence of six BVMOs in M. tuberculosis, including MymA, EthA, and Rv0565c, which are involved in the activation of the second-line prodrug ethionamide, as well as the novel BVMO Rv0892. Through a combination of in silico characterization and in vitro validation, we elucidated the structural framework and substrate preferences of these BVMOs. Particularly, MymA exhibited enhanced capacity and a distinct selectivity profile towards ligands, supporting the understanding of its specific catalytic site topology. These findings contribute to a better comprehension of the structure-function relationship in BVMOs and expand the repertoire of selective and/or overlapping BVMOs for improving anti-TB therapy.

MSPHERE (2022)

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Article Multidisciplinary Sciences

Exploring machine learning: a scientometrics approach using bibliometrix and VOSviewer

David Opeoluwa Oyewola et al.

Summary: This study applies machine learning to solve complex problems and investigates the global structure of the machine learning field, examining collaborative relationships among institutions and countries. The findings provide valuable insights for future research in this rapidly developing field.

SN APPLIED SCIENCES (2022)

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Article Multidisciplinary Sciences

Nanopore sequencing of a monkeypox virus strain isolated from a pustular lesion in the Central African Republic

Mathias Vandenbogaert et al.

Summary: Monkeypox is an emerging and neglected zoonotic disease in Central Africa. This study evaluated the use of the MinION real-time sequencer and different polishing tools to sequence the monkeypox virus genome and found the best combination to reduce insertion/deletion errors.

SCIENTIFIC REPORTS (2022)

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Correction Biochemistry & Molecular Biology

Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus (vol 28, pg 1569, 2022)

Joana Isidro et al.

NATURE MEDICINE (2022)

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Article Mathematics, Interdisciplinary Applications

Bioinformatics, Computational Informatics, and Modeling Approaches to the Design of mRNA COVID-19 Vaccine Candidates

Olugbenga Oluseun Oluwagbemi et al.

Summary: This article describes the development of a multi-epitope mRNA vaccine against the spike glycoproteins of circulating SARS-CoV-2 variants in selected African countries using bioinformatics and immunoinformatics approaches. The vaccine candidate shows good population coverage and immunogenic properties, providing a potential solution to the global threat posed by SARS-CoV-2.

COMPUTATION (2022)

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Article Computer Science, Artificial Intelligence

Lung nodules detection using semantic segmentation and classification with optimal features

Talha Meraj et al.

Summary: This study proposed a framework for precisely detecting and classifying lung cancer nodules, achieving good experimental results by using a variety of techniques and algorithms to process image data.

NEURAL COMPUTING & APPLICATIONS (2021)

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Article Public, Environmental & Occupational Health

A Tale of Two Viruses: Coinfections of Monkeypox and Varicella Zoster Virus in the Democratic Republic of Congo

Christine M. Hughes et al.

Summary: Recent enhanced monkeypox surveillance in the Democratic Republic of Congo has identified cases of monkeypox and varicella zoster virus coinfections. Coinfections were more likely to exhibit symptoms compared to cases with VZV alone, but less severe compared to cases with MPX alone. This study highlights the importance of ongoing surveillance to assess variations in coinfected cases over time.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2021)

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Article Computer Science, Information Systems

Predicting COVID-19 Cases in South Korea with All K-Edited Nearest Neighbors Noise Filter and Machine Learning Techniques

David Opeoluwa Oyewola et al.

Summary: Filtering noise from the dataset can improve the accuracy of machine learning algorithms for predicting COVID-19 cases. After performing noise filtering operations, machine learning techniques achieved high accuracy in predicting COVID-19 cases.

INFORMATION (2021)

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Article

COVID-19 Risk Factors, Economic Factors, and Epidemiological Factors nexus on Economic Impact: Machine Learning and Structural Equation Modelling Approaches

David Opeoluwa Oyewola et al.

Journal of Nigerian Society of Physical Sciences (2021)

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Article Biochemistry & Molecular Biology

A deep learning system for differential diagnosis of skin diseases

Yuan Liu et al.

NATURE MEDICINE (2020)

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Review Infectious Diseases

Transmission of SARS-CoV-2: an update of current literature

Kishan P. Patel et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2020)

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Editorial Material Public, Environmental & Occupational Health

Modelling human-to-human transmission of monkeypox

Rebecca Grant et al.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2020)

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Article Multidisciplinary Sciences

MAVSCOT: A fuzzy logic-based HIV diagnostic system with indigenous multi-lingual interfaces for rural Africa

Olugbenga Oluseun Oluwagbemi et al.

PLOS ONE (2020)

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Review Virology

Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution

Emmanuel Alakunle et al.

VIRUSES-BASEL (2020)

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Review Infectious Diseases

A systematic review of the epidemiology of human monkeypox outbreaks and implications for outbreak strategy

Ellen M. Beer et al.

PLOS NEGLECTED TROPICAL DISEASES (2019)

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Article Health Care Sciences & Services

Recurrent Ebolavirus disease in the Democratic Republic of Congo: update and challenges

Joseph Inungu et al.

AIMS PUBLIC HEALTH (2019)

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Article Medicine, General & Internal

Beyond the Dirty Dozen: A Proposed Methodology for Assessing Future Bioweapon Threats

Theodore J. Cieslak et al.

MILITARY MEDICINE (2018)

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Article Biochemical Research Methods

Flexible docking-based molecular dynamics simulation of natural product compounds and Ebola virus Nucleocapsid (EBOV NP): a computational approach to discover new drug for combating Ebola

Mochammad Arfin Fardiansyah Nasution et al.

BMC BIOINFORMATICS (2018)

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Article Medicine, Research & Experimental

Transmission and Institutional Infection Control of Tuberculosis

Edward A. Nardell

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

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Article Immunology

Extended Human-to-Human Transmission during a Monkeypox Outbreak in the Democratic Republic of the Congo

Leisha Diane Nolen et al.

EMERGING INFECTIOUS DISEASES (2016)

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Article Economics

A comparison of AdaBoost algorithms for time series forecast combination

Devon K. Barrow et al.

INTERNATIONAL JOURNAL OF FORECASTING (2016)

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Article Multidisciplinary Sciences

Innovative Technological Approach to Ebola Virus Disease Outbreak Response in Nigeria Using the Open Data Kit and Form Hub Technology

Daniel Tom-Aba et al.

PLOS ONE (2015)

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Proceedings Paper Environmental Sciences

Ordinary Least Squares Regression Method Approach for Site Selection of Automated Teller Machines (ATMs)

Kubra Bilginol et al.

SPATIAL STATISTICS CONFERENCE 2015, PART 1 (2015)

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ANOSPEX: A Stochastic, Spatially Explicit Model for Studying Anopheles Metapopulation Dynamics

Olugbenga O. Oluwagbemi et al.

PLOS ONE (2013)

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Article Public, Environmental & Occupational Health

Effects of georeferencing effort on mapping monkeypox case distributions and transmission risk

R. Ryan Lash et al.

INTERNATIONAL JOURNAL OF HEALTH GEOGRAPHICS (2012)

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Article Immunology

Status of human monkeypox: clinical disease, epidemiology and research

Inger K. Damon

VACCINE (2011)

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Article Multidisciplinary Sciences

Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo

Anne W. Rimoin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Article Dentistry, Oral Surgery & Medicine

Tuberculosis epidemiology, diagnosis and infection control recommendations for dental settings An update on the Centers for Disease Control and Prevention guidelines

Jennifer L. Cleveland et al.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION (2009)

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Review Immunology

Monkeypox virus and insights into its immunomodulatory proteins

Jessica R. Weaver et al.

IMMUNOLOGICAL REVIEWS (2008)

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Efficiency of human immunodeficiency virus transmission through injections and other medical procedures: Evidence, estimates, and unfinished business

David Gisselquist et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2006)

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New considerations in infectious disease outbreaks: The threat of genetically modified microbes

JR Gilsdorf et al.

CLINICAL INFECTIOUS DISEASES (2005)

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Human monkeypox: an emerging zoonosis

DB Di Giulio et al.

LANCET INFECTIOUS DISEASES (2004)

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Ensemble Machine Learning for Monkeypox Transmission Time Series Forecasting

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