4.7 Article

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

Related references

Note: Only part of the references are listed.
Editorial Material Pharmacology & Pharmacy

Perspectives on Model-Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations

Franziska Kluwe et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)

Article Pharmacology & Pharmacy

Development and verification of an endogenous PBPK model to inform hydrocortisone replacement dosing in children and adults with cortisol deficiency

Jennifer J. Bonner et al.

Summary: This study developed a physiologically based pharmacokinetic model to predict the pharmacokinetics of hydrocortisone in healthy adults, children, and adults with adrenal insufficiency. The model accurately predicted the pharmacokinetics of both immediate-release and modified-release formulations across different age groups.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

Article Endocrinology & Metabolism

Paediatric population pharmacokinetic modelling to assess hydrocortisone replacement dosing regimens in young children

Robin Michelet et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2020)

Article Endocrinology & Metabolism

Longitudinal Assessment of Illnesses, Stress Dosing, and Illness Sequelae in Patients With Congenital Adrenal Hyperplasia

Diala El-Maouche et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

Article Pharmacology & Pharmacy

The use of PBPK modeling across the pediatric age range using propofol as a case

Robin Michelet et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2018)

Review Pharmacology & Pharmacy

PBPK in Preterm and Term Neonates: A Review

Robin Michelet et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Article Endocrinology & Metabolism

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline

Stefan R. Bornstein et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

Review Endocrinology & Metabolism

Diagnosis and management of adrenal insufficiency

Irina Bancos et al.

LANCET DIABETES & ENDOCRINOLOGY (2015)

Review Pharmacology & Pharmacy

Combining the 'bottom up' and 'top down' approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

Nikolaos Tsamandouras et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)

Article Endocrinology & Metabolism

Variation in absorption and half-life of hydrocortisone influence plasma cortisol concentrations

Peter C. Hindmarsh et al.

CLINICAL ENDOCRINOLOGY (2015)

Article Endocrinology & Metabolism

Diminished 11β-Hydroxysteroid Dehydrogenase Type 2 Activity Is Associated With Decreased Weight and Weight Gain Across the First Year of Life

Samantha L. Rogers et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)

Article Endocrinology & Metabolism

Increased Mortality in Patients With Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

Henrik Falhammar et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)

Article Endocrinology & Metabolism

Clinical Characteristics of a Cohort of 244 Patients with Congenital Adrenal Hyperplasia

Gabriela P. Finkielstain et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Review Anesthesiology

Role of modeling and simulation in pediatric investigation plans

Efthymios Manolis et al.

PEDIATRIC ANESTHESIA (2011)

Article Endocrinology & Metabolism

Management of the child with congenital adrenal hyperplasia

Peter C. Hindmarsh

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2009)

Letter Pharmacology & Pharmacy

Development of CYP2D6 and CYP3A4 in the first year of life

T. N. Johnson et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)

Article Endocrinology & Metabolism

Sexual dimorphism in cortisol secretion starts after age 10 in healthy children: urinary cortisol metabolite excretion rates during growth

Stefan A. Wudy et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)

Article Biochemistry & Molecular Biology

Ontogeny of human hepatic cytochromes P450

Ronald N. Hines

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2007)

Article Chemistry, Multidisciplinary

Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide

Karl Brendel et al.

PHARMACEUTICAL RESEARCH (2006)

Review Pharmacology & Pharmacy

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

Trevor N. Johnson et al.

CLINICAL PHARMACOKINETICS (2006)

Review Medicine, General & Internal

Congenital adrenal hyperplasia

DP Merke et al.

LANCET (2005)

Review Medicine, General & Internal

Developmental pharmacology - Drug disposition, action, and therapy in infants and children

GL Kearns et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)