4.6 Review

Advances in the Clinical Application of Histamine and Diamine Oxidase (DAO) Activity: A Review

Related references

Note: Only part of the references are listed.
Article Nutrition & Dietetics

Basal Serum Diamine Oxidase Levels as a Biomarker of Histamine Intolerance: A Retrospective Cohort Study

Valentina Cucca et al.

Summary: This study aimed to evaluate the clinical usefulness and consistency of serum DAO value ranges and verify their predictive value for treatment response in HIT patients. The results showed that the severity of symptoms in HIT patients was correlated with the degree of DAO deficiency. Patients with DAO values between 3 and 10 U/mL showed the best response to treatment.

NUTRIENTS (2022)

Article Nutrition & Dietetics

The Rate of Histamine Degradation by Diamine Oxidase Is Compromised by Other Biogenic Amines

Sonia Sanchez-Perez et al.

Summary: There are uncertainties regarding the onset of histamine adverse effects that still require further research. This study investigated the interference of different amines on the rate of histamine degradation by the enzyme DAO. The results showed that certain amines significantly delayed histamine degradation, while others inhibited it, suggesting a possible explanation for the variable susceptibility to dietary histamine.

FRONTIERS IN NUTRITION (2022)

Article Pharmacology & Pharmacy

Nafamostat is a Potent Human Diamine Oxidase Inhibitor Possibly Augmenting Hypersensitivity Reactions during Nafamostat Administration

Thomas Boehm et al.

Summary: Nafamostat is a potent human DAO inhibitor and may increase the severity of anaphylactic reactions by interfering with DAO-mediated extracellular histamine degradation.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2022)

Article Nutrition & Dietetics

Toward Oral Supplementation of Diamine Oxidase for the Treatment of Histamine Intolerance

Lucas Kettner et al.

Summary: A new diamine oxidase (DAO-1) was discovered in yeast, which has the potential to treat histamine intolerance by oral supplementation under simulated intestinal conditions.

NUTRIENTS (2022)

Article Oncology

Serum diamine oxidase activity derived from response to chemotherapy affects adverse events and serum amino acid levels

Yuta Sato et al.

Summary: The study suggests that serum DAO activity may serve as a predictor of chemotherapy response in patients with EC. Higher DAO activity levels were associated with maintained amino acid absorption capacity, potentially contributing to anti-inflammatory effects and a reduction in adverse events.

SUPPORTIVE CARE IN CANCER (2022)

Review Biotechnology & Applied Microbiology

Recent advances in the application of microbial diamine oxidases and other histamine-oxidizing enzymes

Lucas Kettner et al.

Summary: Consuming foods with high histamine levels can cause allergy-like symptoms if the body cannot sufficiently break down histamine. This can lead to histamine intolerance. One solution is to produce histamine-free or reduced foods and supplement with exogenous DAO. Microbial DAOs show promise due to their efficient biotechnological production capabilities, but their biochemical properties are important for successful application.

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2022)

Article Nutrition & Dietetics

The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study

Sonia Sanchez-Perez et al.

Summary: Restrictive diets can change the composition of intestinal microbiota and have an impact on the treatment of histamine intolerance. This preliminary study found that a dietary treatment for histamine intolerance led to a reduction in histamine-secreting bacteria and an increase in a bacterial group associated with gut health.

FRONTIERS IN NUTRITION (2022)

Review Food Science & Technology

Considering histamine in functional gastrointestinal disorders

Wolfgang J. Schnedl et al.

Summary: In western countries, a significant portion of the population may experience adverse reactions to certain food components, leading to various gastrointestinal issues. Thus, a thorough diagnostic workup is necessary for managing patients with functional gastrointestinal complaints, including consideration of individual tolerance to different food components.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2021)

Article Biochemistry & Molecular Biology

Design and development of novel fasudil derivatives as potent antibreast cancer agent that improves intestinal flora and intestinal barrier function in rats

Jinghui Liang et al.

Summary: This study aimed to develop novel fasudil derivatives with substituted thiazoles as potent anti-breast cancer agents. The compounds demonstrated potent inhibition of ROCK1 compared to ROCK2 and showed significant improvement in bodyweight and reduction in oxidative stress in rats. Additionally, the derivatives improved intestinal flora and barrier function, showcasing their potential as effective anti-BC agents.

CHEMICAL BIOLOGY & DRUG DESIGN (2021)

Review Nutrition & Dietetics

Histamine Intolerance Originates in the Gut

Wolfgang J. Schnedl et al.

Summary: Histamine intolerance is primarily caused by a deficiency of the enzyme diamine oxidase in the gastrointestinal tract, leading to improper breakdown and absorption of histamine. Symptoms are non-specific and can affect the GI tract and other organs. Diagnosis is challenging but relies on detailed patient history and potentially low serum DAO values. Dietary intervention and supplementation with DAO capsules can help alleviate HIT symptoms.

NUTRIENTS (2021)

Article Immunology

Tremella fuciformis Polysaccharides Inhibited Colonic Inflammation in Dextran Sulfate Sodium-Treated Mice via Foxp3+T Cells, Gut Microbiota, and Bacterial Metabolites

Yingyin Xu et al.

Summary: This study identified the protective effects of Tremella fuciformis polysaccharides (TPs) against colitis in mice, demonstrating that TPs could alleviate inflammation by modulating immune responses and restoring gut microbiota and microbial metabolites.

FRONTIERS IN IMMUNOLOGY (2021)

Review Nutrition & Dietetics

Histamine Intolerance-The More We Know the Less We Know. A Review

Martin Hrubisko et al.

Summary: Food intake can trigger adverse reactions, with food intolerance being an abnormal non-immunological response to ingested food or its components. Histamine intolerance is a type of food intolerance that is difficult to diagnose and requires a complex approach for treatment, including low-histamine diet and DAO supplementation.

NUTRIENTS (2021)

Article Food Science & Technology

Evaluation of porcine diamine oxidase for the conversion of histamine in food-relevant amounts

Lucas Kettner et al.

JOURNAL OF FOOD SCIENCE (2020)

Article Multidisciplinary Sciences

Regulation of histamine and diamine oxidase in patients undergoing orthotopic liver transplantation

Judith Schiefer et al.

SCIENTIFIC REPORTS (2020)

Review Biochemistry & Molecular Biology

Histamine Intolerance: The Current State of the Art

Oriol Comas-Baste et al.

BIOMOLECULES (2020)

Article Nutrition & Dietetics

Histamine-reduced diet and increase of serum diamine oxidase correlating to diet compliance in histamine intolerance

Sonja Lackner et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2019)

Review Biochemistry & Molecular Biology

The Association Between Serum Magnesium and Premenstrual Syndrome: a Systematic Review and Meta-Analysis of Observational Studies

Mohsen Moslehi et al.

BIOLOGICAL TRACE ELEMENT RESEARCH (2019)

Article Pharmacology & Pharmacy

Enzyme nanovehicles: Histaminase and catalase delivered in nanoparticulate chitosan

Mihaela Leonida et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Article Food Science & Technology

Diamine oxidase supplementation improves symptoms in patients with histamine intolerance

Wolfgang J. Schnedl et al.

FOOD SCIENCE AND BIOTECHNOLOGY (2019)

Review Nutrition & Dietetics

Food Intolerances

Caroline J. Tuck et al.

NUTRIENTS (2019)

Article Otorhinolaryngology

Diamine oxidase enzyme: a novel biomarker in respiratory allergy

Maged M. Refaat et al.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2019)

Article Biochemical Research Methods

In vitro determination of diamine oxidase activity in food matrices by an enzymatic assay coupled to UHPLC-FL

Oriol Comas-Baste et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)

Article Gastroenterology & Hepatology

Evaluation of symptoms and symptom combinations in histamine intolerance

Wolfgang J. Schnedl et al.

INTESTINAL RESEARCH (2019)

Article Biochemistry & Molecular Biology

Low serum diamine oxidase (DAO) activity levels in patients with migraine

Joan Izquierdo-Casas et al.

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2018)

Article Allergy

Diamine Oxidase Supplementation in Chronic Spontaneous Urticaria: A Randomized, Double-Blind Placebo-Controlled Study

Mona-Rita Yacoub et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2018)

Article Nutrition & Dietetics

Postoperative symbiotic in patients with head and neck cancer: a double-blind randomised trial

Priscilla C. Lages et al.

BRITISH JOURNAL OF NUTRITION (2018)

Article Food Science & Technology

Tyramine and histamine risk assessment related to consumption of dry fermented sausages by the Spanish population

M. L. Latorre-Moratalla et al.

FOOD AND CHEMICAL TOXICOLOGY (2017)

Article Chemistry, Analytical

New approach for the diagnosis of histamine intolerance based on the determination of histamine and methylhistamine in urine

Oriol Comas-Baste et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2017)

Article Medical Laboratory Technology

Quantification of human diamine oxidase

Thomas Boehm et al.

CLINICAL BIOCHEMISTRY (2017)

Article Genetics & Heredity

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Padhraig Gormley et al.

NATURE GENETICS (2016)

Review Allergy

Histamine, histamine intoxication and intolerance

E. Kovacova-Hanuskova et al.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA (2015)

Article Gastroenterology & Hepatology

Serum diamine oxidase activity as a predictor of gastrointestinal toxicity and malnutrition due to anticancer drugs

Jinsei Miyoshi et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2015)

Article Emergency Medicine

Diamine oxidase in diagnosis of acute mesenteric ischemia

Keziban Ucar Karabulut et al.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2013)

Article Medical Laboratory Technology

Effect of the menstrual cycle on serum diamine oxidase levels in healthy women

Yasuhiro Hamada et al.

CLINICAL BIOCHEMISTRY (2013)

Article Clinical Neurology

New tools for studying old questions: antibodies for human diamine oxidase

Hubert G. Schwelberger et al.

JOURNAL OF NEURAL TRANSMISSION (2013)

Article Medicine, General & Internal

A combination of plasma DAO and citrulline levels as a potential marker for acute mesenteric ischemia

Ridvan Cakmaz et al.

LIBYAN JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

Serum diamine oxidase activity as a diagnostic test for histamine intolerance

Ema Music et al.

WIENER KLINISCHE WOCHENSCHRIFT (2013)

Article Chemistry, Analytical

Ion mobility spectrometry for monitoring diamine oxidase activity

Sergio Armenta et al.

ANALYST (2012)

Review Gastroenterology & Hepatology

Importance of Disrupted Intestinal Barrier in Inflammatory Bowel Diseases

Sa'ad Y. Salim et al.

INFLAMMATORY BOWEL DISEASES (2011)

Article Gastroenterology & Hepatology

Clinical significance of serum diamine oxidase activity in inflammatory bowel disease

Yusuke Honzawa et al.

INFLAMMATORY BOWEL DISEASES (2010)

Article Biochemistry & Molecular Biology

Structure and Inhibition of Human Diamine Oxidase

Aaron P. McGrath et al.

BIOCHEMISTRY (2009)

Article Gastroenterology & Hepatology

Effect of Lianshu preparation on lipopolysaccharide-induced diarrhea in rats

Jun Liu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2009)

Review Obstetrics & Gynecology

Effects of histamine and diamine oxidase activities on pregnancy: a critical review

Laura Maintz et al.

HUMAN REPRODUCTION UPDATE (2008)

Review Nutrition & Dietetics

Histamine and histamine intolerance

Laura Maintz et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2007)

Article Allergy

The prevalence of food hypersensitivity in an unselected population of children and adults

M Osterballe et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2005)

Article Biochemistry & Molecular Biology

Human kidney diamine oxidase: heterologous expression, purification, and characterization

BO Elmore et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2002)