4.6 Article

Randomized phase II study of capecitabine plus cisplatin with or without sorafenib in patients with metastatic gastric cancer (STARGATE)

Related references

Note: Only part of the references are listed.
Review Oncology

The integration of immune checkpoint inhibitors with VEGF targeted agents in advanced gastric and gastroesophageal adenocarcinoma: a review on the rationale and results of early phase trials

Anwaar Saeed et al.

Summary: Various targeted therapies, including anti-angiogenic agents and immune checkpoint inhibitors, have shown efficacy in patients with advanced gastric cancer and gastroesophageal junction adenocarcinoma. Combining VEGF inhibition with immune checkpoint blockade has shown promising clinical activity, indicating a potential dual blockade strategy in this patient population.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Multidisciplinary Sciences

The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer

Yelena Y. Janjigian et al.

Summary: The study results demonstrate that adding pembrolizumab to trastuzumab and chemotherapy significantly reduces tumor size, induces complete responses in some patients, and improves objective response rate in HER2-positive gastric or gastro-oesophageal junction adenocarcinoma.

NATURE (2021)

Article Medicine, General & Internal

First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial

Yelena Y. Janjigian et al.

Summary: Nivolumab plus chemotherapy showed superior overall survival and progression-free survival compared to chemotherapy alone in previously untreated patients with advanced gastric, gastro-oesophageal junction, or oesophageal adenocarcinoma, indicating it as a new standard first-line treatment option with acceptable safety profile.

LANCET (2021)

Article Oncology

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

Dal Fukurnura et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Article Medicine, General & Internal

Capecitabine and oxaliplatin for advanced esophagogastric cancer

David Cunningham et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Multidisciplinary Sciences

Patterns of somatic mutation in human cancer genomes

Christopher Greenman et al.

NATURE (2007)

Article Oncology

Phase II study of sorafenib in patients with advanced hepatocellular carcinoma

Ghassan K. Abou-Alfa et al.

JOURNAL OF CLINICAL ONCOLOGY (2006)

Article Endocrinology & Metabolism

Sex steroid hormone receptors in human thymoma

H Ishibashi et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)