☆ 4.6 Article

A Novel Integrated Transdermal Drug Delivery System with Micropump and Microneedle Made from Polymers

MICROMACHINES (2023)

Related references

Note: Only part of the references are listed.

Review Chemistry, Multidisciplinary

Recent advances in polymeric transdermal drug delivery systems

Farzaneh Sabbagh et al.

Summary: Transdermal drug delivery is an effective method with advantages of avoiding liver and gastrointestinal side effects, maintaining a steady rate of drug delivery, and utilizing patches for administration. With effective design and evaluation, a wide range of drugs can now be administered using this valuable advanced technology, which has roots dating back to ancient China.

JOURNAL OF CONTROLLED RELEASE (2022)

Add to Collection

Article Chemistry, Medicinal

A Wirelessly Controlled Scalable 3D-Printed Microsystem for Drug Delivery

Farzad Forouzandeh et al.

Summary: A 3D-printed microsystem for drug delivery, including a refillable microreservoir and a phase-change peristaltic micropump, was optimized for murine inner ear drug delivery and demonstrated favorable results in long-term subcutaneous implantation experiments. Real-time monitoring during drug infusion showed similar results with syringe pump infusion, indicating the scalability of this low-cost design and fabrication methodology for different clinical applications and delivery sites.

PHARMACEUTICALS (2021)

Add to Collection

Review Nanoscience & Nanotechnology

Targeted drug delivery strategies for precision medicines

Mandana T. Manzari et al.

Summary: Precision medicine offers personalized treatment strategies for individual patients, especially in the field of cancer therapy. While there have been some clinical successes, challenges such as drug toxicities and resistance still hinder the full potential of precision medicine. Advanced drug delivery materials and approaches provide opportunities to improve therapeutic outcomes and overcome pharmacological issues in cancer treatment.

NATURE REVIEWS MATERIALS (2021)

Add to Collection

Article Automation & Control Systems

Fabrication of monolithic SU-8 microneedle arrays having different needle geometries using a simplified process

A. P. Ajay et al.

Summary: Transdermal drug delivery using hollow microneedles is made possible by the use of a single-step spin coating process to achieve the desired thickness of a biocompatible photopolymer, SU-8, while using UV lithography to create a monolithic microneedle array. The fabricated microneedles exhibit robust mechanical properties and low resistance to fluid flow, making them suitable for drug delivery applications.

INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY (2021)

Add to Collection

Article Biophysics

A MEMS-Based Drug Delivery Device With Integrated Microneedle Array-Design and Simulation

Farshid Meshkinfam et al.

Summary: The use of microneedle-based MEMS drug delivery devices provides an effective treatment for diabetes, with safe, painless and robust injection application. The positive volumetric insulin pump design involves a Multiphysics problem, studied through simulation systems for performance evaluation of a MEMS-based insulin micropump with piezoelectric actuator.

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2021)

Add to Collection

Review Engineering, Electrical & Electronic

Microdosing for drug delivery application-A review

Agnes Beate Bussmann et al.

Summary: Research on microfluidic actuators for drug dosing applications is increasing, with micropumps showing promise in reducing size and energy consumption. Despite advantages, industrial microdosing units are limited and micropump technology is not widely applied. This work analyzes specific challenges and requirements in medical dosing, evaluates mechanical micropumps for drug administration, and presents technical solutions to ensure fluidic performance and meet medical microdosing requirements.

SENSORS AND ACTUATORS A-PHYSICAL (2021)

Add to Collection

Review Nanoscience & Nanotechnology

Engineering Microneedle Patches for Improved Penetration: Analysis, Skin Models and Factors Affecting Needle Insertion

Pooyan Makvandi et al.

Summary: Transdermal microneedle patches are a promising tool for delivering active compounds into the skin, requiring sufficient skin penetration to ensure cargo release at predetermined locations. Pain signal and management during microneedle and hypodermic needle application are compared, alongside discussions on factors affecting insertion and recent strategies to improve skin penetration.

NANO-MICRO LETTERS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

A Fully Integrated Closed-Loop System Based on Mesoporous Microneedles-Iontophoresis for Diabetes Treatment

Xiangling Li et al.

Summary: This study developed a fully integrated wearable closed-loop system based on a mini-invasive microneedle platform for in situ diabetic sensing and treatment, with features such as painless skin penetration, electrical insulin delivery control, and glucose monitoring. It shows great potential in improving the treatment of diabetic patients.

ADVANCED SCIENCE (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Advances in Valveless Piezoelectric Pumps

Qiufeng Yan et al.

Summary: Piezoelectric pump design is a hot research topic in the microfluidic field, with the valveless piezoelectric pump being an important branch due to its ability to avoid pump-lagging issues. This paper summarizes the development of valveless piezoelectric pumps, introduces different configurations, elaborates on structure and material, evaluates output performance, and compares flow rates of different types of pumps, providing insights for future research.

APPLIED SCIENCES-BASEL (2021)

Add to Collection

Review Biotechnology & Applied Microbiology

Gut Check Time: Antibiotic Delivery Strategies to Reduce Antimicrobial Resistance

Stephen A. Kelly et al.

TRENDS IN BIOTECHNOLOGY (2020)

Add to Collection

Review Automation & Control Systems

Recent trends in mechanical micropumps and their applications: A review

S. Mohith et al.

MECHATRONICS (2019)

Add to Collection

Article Engineering, Electrical & Electronic

Feasibility Studies on Nafion Membrane Actuated Micropump Integrated With Hollow Microneedles for Insulin Delivery Device

Richa Mishra et al.

JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2019)

Add to Collection

Article Engineering, Electrical & Electronic

Design and Scalable Fabrication of Hollow SU-8 Microneedles for Transdermal Drug Delivery

Richa Mishra et al.

IEEE SENSORS JOURNAL (2018)

Add to Collection

Article Chemistry, Analytical

In Vivo Experimental Study of Noninvasive Insulin Microinjection through Hollow Si Microneedle Array

Drago Resnik et al.

MICROMACHINES (2018)

Add to Collection

Article Nanoscience & Nanotechnology

Experimental characterization of piezoelectrically actuated micromachined silicon valveless micropump

Shelly Aggarwal et al.

MICROFLUIDICS AND NANOFLUIDICS (2017)

Add to Collection

Review Biochemical Research Methods

Recent advances in the design of polymeric microneedles for transdermal drug delivery and biosensing

Min Wang et al.

LAB ON A CHIP (2017)

Add to Collection

Review Polymer Science

MEMS-Based Controlled Drug Delivery Systems: A Short Review

Suprio R. Paul et al.

POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING (2016)

Add to Collection

Review Materials Science, Multidisciplinary

Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

Eneko Larraneta et al.

MATERIALS SCIENCE & ENGINEERING R-REPORTS (2016)

Add to Collection

Article Pharmacology & Pharmacy

Hollow polymer microneedles array resistance and insertion tests

Marion Sausse Lhernould et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

Add to Collection

Article Engineering, Electrical & Electronic

Analytical modeling, simulations and experimental studies of a PZT actuated planar valveless PDMS micropump

S. Singh et al.

SENSORS AND ACTUATORS A-PHYSICAL (2015)

Add to Collection

Article Engineering, Biomedical

Structural characterization and in-vivo reliability evaluation of silicon microneedles

Conor O'Mahony

BIOMEDICAL MICRODEVICES (2014)

Add to Collection

Article Pharmacology & Pharmacy

A proposed model membrane and test method for microneedle insertion studies

Eneko Larraneta et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)

Add to Collection

Article Engineering, Electrical & Electronic

Fabrication and analysis of hollow microneedles and polymeric piezoelectric valveless micropump for transdermal drug-delivery system

M. W. Ashraf et al.

IET COMMUNICATIONS (2012)

Add to Collection

Article Biochemistry & Molecular Biology

A Comparative Study of Nozzle/Diffuser Micropumps with Novel Valves

Kai-Shing Yang et al.

MOLECULES (2012)

Add to Collection

Article Instruments & Instrumentation

An efficient numerical method for predicting the performance of valveless micropump

Paul Braineard Eladi et al.

SMART MATERIALS AND STRUCTURES (2012)

Add to Collection

Review Pharmacology & Pharmacy

Drug delivery systems: An updated review

Gaurav Tiwari et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2012)

Add to Collection

Article Engineering, Electrical & Electronic

Parametric characterization of piezoelectric valveless micropump

Parikshit Verma et al.

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS (2011)

Add to Collection

Article Engineering, Electrical & Electronic

The effects of adhesion energy on the fabrication of high-aspect-ratio SU-8 microstructures

Kyu-Youn Hwang et al.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2010)

Add to Collection

Review Nanoscience & Nanotechnology

Steady and unsteady flow analysis in microdiffusers and micropumps: a critical review

Majid Nabavi

MICROFLUIDICS AND NANOFLUIDICS (2009)

Add to Collection

Article Anesthesiology

Effect of microneedle design on pain in human volunteers

Harvinder S. Gill et al.

CLINICAL JOURNAL OF PAIN (2008)

Add to Collection

Review Biotechnology & Applied Microbiology

Transdermal drug delivery

Mark R. Prausnitz et al.

NATURE BIOTECHNOLOGY (2008)

Add to Collection

Review Chemistry, Analytical

MEMS-based micropumps in drug delivery and biomedical applications

A. Nisar et al.

SENSORS AND ACTUATORS B-CHEMICAL (2008)

Add to Collection

Article Engineering, Electrical & Electronic

Penetration-enhanced ultrasharp microneedles and prediction on skin interaction for efficient transdermal drug delivery

Niclas Roxhed et al.

JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2007)

Add to Collection

Review Engineering, Biomedical

The mechanical properties of the skin epidermis in relation to targeted gene and drug delivery

Mark A. F. Kendall et al.

BIOMATERIALS (2007)

Add to Collection

Article Nanoscience & Nanotechnology

A PZT insulin pump integrated with a silicon microneedle array for transdermal drug delivery

Bin Ma et al.

MICROFLUIDICS AND NANOFLUIDICS (2006)

Add to Collection

Article Engineering, Electrical & Electronic

Numerical characterization of the flow rectification of dynamic microdiffusers

C-L Sun et al.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2006)

Add to Collection

Article Engineering, Electrical & Electronic

Sharp beveled tip hollow microneedle arrays fabricated by LIGA and 3D soft lithography with polyvinyl alcohol

F Pérennès et al.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2006)

Add to Collection

Review Pharmacology & Pharmacy

Integrated microsystems for controlled drug delivery

SZ Razzacki et al.

ADVANCED DRUG DELIVERY REVIEWS (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.