☆ 4.6 Review

Exhaled Biomarkers for Point-of-Care Diagnosis: Recent Advances and New Challenges in Breathomics

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Summary: HO-1, known for its antioxidant properties, has also been shown to have anti-inflammatory effects, making it a potential treatment for chronic inflammatory and autoimmune diseases. Inducing HO-1 has therapeutic potential, but there are challenges to translating this treatment to clinical use.

NATURE REVIEWS IMMUNOLOGY (2021)

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Review Environmental Sciences

'Smoging kills' Effects of air pollution on human respiratory system

Anna Grzywa-Celinska et al.

ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE (2020)

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Review Chemistry, Medicinal

Inducible nitric oxide synthase: Regulation, structure, and inhibition

Maris A. Cinelli et al.

MEDICINAL RESEARCH REVIEWS (2020)

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Article Respiratory System

Measurement of Fractional Exhaled Nitric Oxide: Comparison of Three Different Analysers

Stephanie Korn et al.

RESPIRATION (2020)

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Review Infectious Diseases

Sniffing animals as a diagnostic tool in infectious diseases

E. Cambau et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

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Editorial Material Allergy

Exhaled Nitric Oxide (eNO) Measurements With the New evernoa Device Are Valid and Reproducible Through an Extended Range of eNO Levels

J. M. Olaguibel

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY (2020)

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Review Physiology

Nitric oxide: To be or not to be an endocrine hormone?

Zahra Bahadoran et al.

ACTA PHYSIOLOGICA (2020)

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Review Respiratory System

Clinical utility of fractional exhaled nitric oxide in severe asthma management

Andrew Menzies-Gow et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

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Review Biochemistry & Molecular Biology

Hydrogen Sulfide in Pharmacotherapy, Beyond the Hydrogen Sulfide-Donors

Ewelina Zaorska et al.

BIOMOLECULES (2020)

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Article Rheumatology

Patients with psoriatic arthritis have higher levels of FeNO than those with only psoriasis, which may reflect a higher prevalence of a subclinical respiratory involvement

Giovanni Damiani et al.

CLINICAL RHEUMATOLOGY (2020)

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Review Biochemistry & Molecular Biology

Applications of Near Infrared Photoacoustic Spectroscopy for Analysis of Human Respiration: A Review

Dan C. Dumitras et al.

MOLECULES (2020)

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Article Oncology

Breath Analysis for Early Detection of Malignant Pleural Mesothelioma: Volatile Organic Compounds (VOCs) Determination and Possible Biochemical Pathways

Alessia Di Gilio et al.

CANCERS (2020)

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Review Biochemistry & Molecular Biology

Cystathionine-beta-synthase: Molecular Regulation and Pharmacological Inhibition

Karim Zuhra et al.

BIOMOLECULES (2020)

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Review Biochemistry & Molecular Biology

Clinical Values of Nitric Oxide Parameters from the Respiratory System

Lauri Lehtimaki et al.

CURRENT MEDICINAL CHEMISTRY (2020)

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Article Neurosciences

Nitric oxide is fundamental to neurovascular coupling in humans

Ryan L. Hoiland et al.

JOURNAL OF PHYSIOLOGY-LONDON (2020)

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Review Pharmacology & Pharmacy

Hydrogen sulfide: An endogenous regulator of the immune system

Nahzli Dilek et al.

PHARMACOLOGICAL RESEARCH (2020)

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Article Biochemical Research Methods

Identification of profiles of volatile organic compounds in exhaled breath by means of an electronic nose as a proposal for a screening method for breast cancer: a case-control study

Lorena Diaz de Leon-Martinez et al.

JOURNAL OF BREATH RESEARCH (2020)

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Article Biochemical Research Methods

Accurate real-time FENO expirograms using complementary optical sensors

Lorenzo S. Petralia et al.

JOURNAL OF BREATH RESEARCH (2020)

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Review Biochemical Research Methods

Exhaled breath analysis using cavity-enhanced optical techniques: a review

Gourab D. Banik et al.

JOURNAL OF BREATH RESEARCH (2020)

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Review Biochemistry & Molecular Biology

Extended Exhaled Nitric Oxide Analysis in Interstitial Lung Diseases: A Systematic Review

Paolo Cameli et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Respiratory System

Predictive Value of Exhaled Nitric Oxide and Blood Eosinophil Count in the Assessment of Airway Eosinophilia in COPD

Balazs Antus et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2020)

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Review Biochemistry & Molecular Biology

Therapeutic Potential of Heme Oxygenase-1 and Carbon Monoxide in Acute Organ Injury, Critical Illness, and Inflammatory Disorders

Stefan W. Ryter

ANTIOXIDANTS (2020)

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Article Pediatrics

Changes in fractional exhaled nitric oxide, exhaled carbon monoxide and pulmonary function during the acute attack, treatment and remission phases of pediatric asthma

Zhichao Xie et al.

TRANSLATIONAL PEDIATRICS (2020)

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Article Health Care Sciences & Services

A randomized controlled trial of a smoking cessation smartphone application with a carbon monoxide checker

Katsunori Masaki et al.

NPJ DIGITAL MEDICINE (2020)

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Article Medicine, Research & Experimental

Hydrogen sulfide therapy: a narrative overview of current research and possible therapeutic implications in future

Yi-Guang Mao et al.

MEDICAL GAS RESEARCH (2020)

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Article Biochemical Research Methods

Impact of breath sampling on exhaled carbon monoxide

Ramin Ghorbani et al.

JOURNAL OF BREATH RESEARCH (2020)

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Article Biochemical Research Methods

Comparison of volatile organic compound profiles in exhaled breath versus plasma headspace in different diseases

David Grove et al.

JOURNAL OF BREATH RESEARCH (2020)

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Article Chemistry, Analytical

Exhaled breath condensate based breath analyser - a disposable hydrogen peroxide sensor and smart analyser

Yu-Chih Chen et al.

ANALYST (2020)

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Review Critical Care Medicine

Carbon monoxide in intensive care medicine-time to start the therapeutic application?!

Ulrich Goebel et al.

INTENSIVE CARE MEDICINE EXPERIMENTAL (2020)

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Article Allergy

A suitable protocol for measuring alveolar nitric oxide in asthma with differing severity to assess peripheral airways inflammation

Zsofia Lazar et al.

JOURNAL OF ASTHMA (2019)

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Article Otorhinolaryngology

Poor Relationship Between Fractionated Exhaled Nitric Oxide and Disease Activity in Eosinophilic Esophagitis

Kimberly Johnson et al.

DYSPHAGIA (2019)

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Review Biochemical Research Methods

Basic characteristics and clinical value of FeNO in smoking asthmatics-a systematic review

Anneli Ahovuo-Saloranta et al.

JOURNAL OF BREATH RESEARCH (2019)

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Article Biochemical Research Methods

Exhaled carbon monoxide levels in obstructive sleep apnoea

Adrian Kis et al.

JOURNAL OF BREATH RESEARCH (2019)

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Review Biochemistry & Molecular Biology

Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress-A New Insight into the Pathophysiology of Vascular Diseases

Tamas Gall et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Environmental Sciences

Winter Exercise Reduces Allergic Airway Inflammation: A Randomized Controlled Study

Johanna Prossegger et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2019)

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Review Biochemistry & Molecular Biology

Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos

Nirmal Robinson et al.

REDOX BIOLOGY (2019)

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Article Oncology

Prediction of response to anti-PD-1 therapy in patients with non-small-cell lung cancer by electronic nose analysis of exhaled breath

R. de Vries et al.

ANNALS OF ONCOLOGY (2019)

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Review Oncology

Accuracy and Methodologic Challenges of Volatile Organic Compound-Based Exhaled Breath Tests for Cancer Diagnosis A Systematic Review and Meta-analysis

George B. Hanna et al.

JAMA ONCOLOGY (2019)

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Article Chemistry, Multidisciplinary

Toward Continuous Monitoring of Breath Biochemistry: A Paper-Based Wearable Sensor for Real-Time Hydrogen Peroxide Measurement in Simulated Breath

Daniela Maier et al.

ACS SENSORS (2019)

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Review Biochemistry & Molecular Biology

Heme oxygenase-1/carbon monoxide as modulators of autophagy and inflammation

Stefan W. Ryter

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)

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Review Chemistry, Medicinal

Carbon monoxide and its donors - their implications for medicine

Weronika Adach et al.

FUTURE MEDICINAL CHEMISTRY (2019)

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Review Cell Biology

Changes in Redox Signaling in the Skeletal Muscle with Aging

Peter Szentesi et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

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Article Chemistry, Analytical

Development of Tin Oxide-Based Nanosensors for Electronic Nose Environmental Applications

Isabel Sayago et al.

BIOSENSORS-BASEL (2019)

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Article Respiratory System

The clinical value of exhaled nitric oxide in patients with lung cancer

Peng-Fei Liu et al.

CLINICAL RESPIRATORY JOURNAL (2018)

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Article Chemistry, Multidisciplinary

Ultra-Low-Power Smart Electronic Nose System Based on Three-Dimensional Tin Oxide Nanotube Arrays

Jiaqi Chen et al.

ACS NANO (2018)

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Article Cell Biology

Carbon monoxide in lung cell physiology and disease

Stefan W. Ryter et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2018)

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Article Public, Environmental & Occupational Health

Exhaled Nitric Oxide is Not a Biomarker for Pulmonary Tuberculosis

Jose W. Lopez et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2018)

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Review Pharmacology & Pharmacy

A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

Chadwick R. Powell et al.

BIOCHEMICAL PHARMACOLOGY (2018)

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Article Pharmacology & Pharmacy

Nitric oxide donors for peripheral artery disease

Debbie Falconer et al.

CURRENT OPINION IN PHARMACOLOGY (2018)

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Review Pharmacology & Pharmacy

Heme Oxygenase and the Skin in Health and Disease

Imre Lorinc Szabo et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

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Article Pharmacology & Pharmacy

Gasotransmitters and the immune system: Mode of action and novel therapeutic targets

Paolo Fagone et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2018)

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Article Cell Biology

Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion

Laszlo Potor et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

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Article Multidisciplinary Sciences

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

Nicole K. Campbell et al.

SCIENTIFIC REPORTS (2018)

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Article Multidisciplinary Sciences

Natural menstrual rhythm and oral contraception diversely affect exhaled breath compositions

Pritam Sukul et al.

SCIENTIFIC REPORTS (2018)

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Review Respiratory System

Exhaled nitric oxide in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

Zhiyu Lu et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)

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Editorial Material Pharmacology & Pharmacy

Emerging Clinical Applications of Heme Oxygenase

David Haines et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

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Article Biochemistry & Molecular Biology

Heme oxygenase-1 protects airway epithelium against apoptosis by targeting the proinflammatory NLRP3-RXR axis in asthma

Jiajia Lv et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

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Review Endocrinology & Metabolism

Review of recent developments in GC-MS approaches to metabolomics-based research

David J. Beale et al.

METABOLOMICS (2018)

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Article Chemistry, Analytical

A Miniaturized Amperometric Hydrogen Sulfide Sensor Applicable for Bad Breath Monitoring

Hithesh K. Gatty et al.

MICROMACHINES (2018)

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Article Health Care Sciences & Services

Using the Inflammacheck Device to Measure the Level of Exhaled Breath Condensate Hydrogen Peroxide in Patients With Asthma and Chronic Obstructive Pulmonary Disease (The EXHALE Pilot Study): Protocol for a Cross-Sectional Feasibility Study

Daniel M. Neville et al.

JMIR RESEARCH PROTOCOLS (2018)

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Article Hematology

Fractional Exhaled Nitric Oxide Measurement in Pulmonary Hypertension: A Follow-Up Study

Nilay Orak Akbay et al.

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS (2018)

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Article Chemistry, Multidisciplinary

Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules

Morad K. Nakhleh et al.

ACS NANO (2017)

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Article Respiratory System

Exhaled breath to screen for malignant pleural mesothelioma: a validation study

Kevin Lamote et al.

EUROPEAN RESPIRATORY JOURNAL (2017)

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Article Respiratory System

A European Respiratory Society technical standard: exhaled biomarkers in lung disease

Ildiko Horvath et al.

EUROPEAN RESPIRATORY JOURNAL (2017)

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Article Critical Care Medicine

Hydrogen Sulfide in Exhaled Gases From Ventilated Septic Neonates and Children: A Preliminary Report

Natalie Bee et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Review Pharmacology & Pharmacy

International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H2S Levels: H2S Donors and H2S Biosynthesis Inhibitors

Csaba Szabo et al.

PHARMACOLOGICAL REVIEWS (2017)

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Review Biochemistry & Molecular Biology

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

Helmut Sies

REDOX BIOLOGY (2017)

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Article Multidisciplinary Sciences

Lung Cancer Screening Based on Type-different Sensor Arrays

Wang Li et al.

SCIENTIFIC REPORTS (2017)

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Article Biochemical Research Methods

Exhaled and nasal nitric oxide in relation to lung function, blood cell counts and disease characteristics in cystic fibrosis

Christina Krantz et al.

JOURNAL OF BREATH RESEARCH (2017)

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Article Infectious Diseases

Reproducibility of African giant pouched rats detecting Mycobacterium tuberculosis

Haylee Ellis et al.

BMC INFECTIOUS DISEASES (2017)

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Article Gastroenterology & Hepatology

Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus

Ali Rezaie et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

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Article Critical Care Medicine

Kinetics of Exhaled Carbon Monoxide After Water-pipe Smoking Indoors and Outdoors

Agnes Juhasz et al.

CHEST (2017)

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Article Biology

Hydrogen sulfide signaling: interactions with nitric oxide and reactive oxygen species

John T. Hancock et al.

SPECIAL ISSUE: RESPIRATORY SCIENCE (2016)

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Article Respiratory System

L-Arginine Pathway in COPD Patients with Acute Exacerbation: A New Potential Biomarker

Istvan Ruzsics et al.

COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2016)

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Article Chemistry, Analytical

Visualization of exhaled hydrogen sulphide on test paper with an ultrasensitive and time-gated luminescent probe

Ruilong Zhang et al.

ANALYST (2016)

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Review Chemistry, Analytical

Electrochemical hydrogen sulfide biosensors

Tailin Xu et al.

ANALYST (2016)

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Article Chemistry, Analytical

Portable and Disposable Paper-Based Fluorescent Sensor for In Situ Gaseous Hydrogen Sulfide Determination in Near Real-Time

Joao Flavio da Silveira Petruci et al.

ANALYTICAL CHEMISTRY (2016)

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Letter Dermatology

Increased airway inflammation in patients with psoriasis

G. Damiani et al.

BRITISH JOURNAL OF DERMATOLOGY (2016)

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Article Environmental Sciences

Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China

Shaowei Wu et al.

ENVIRONMENT INTERNATIONAL (2016)

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Review Chemistry, Analytical

Understanding the Potential of WO3 Based Sensors for Breath Analysis

Anna Staerz et al.

SENSORS (2016)

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Article Biochemical Research Methods

Association between exhaled inflammatory markers and asthma control in children

D. Van Vliet et al.

JOURNAL OF BREATH RESEARCH (2016)

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Review Engineering, Biomedical

Fractional exhaled nitric oxide-measuring devices: technology update

Mauro Maniscalco et al.

MEDICAL DEVICES-EVIDENCE AND RESEARCH (2016)

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Article Biochemical Research Methods

Hydrogen sulphide in exhaled breath: a potential biomarker for small intestinal bacterial overgrowth in IBS

Gourab Dutta Banik et al.

JOURNAL OF BREATH RESEARCH (2016)

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Article Urology & Nephrology

Olfactory System of Highly Trained Dogs Detects Prostate Cancer in Urine Samples

Gianluigi Taverna et al.

JOURNAL OF UROLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Electronic nose analysis of exhaled breath to diagnose ventilator-associated pneumonia

R. M. Schnabel et al.

RESPIRATORY MEDICINE (2015)

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Article Endocrinology & Metabolism

Dogs Can Be Successfully Trained to Alert to Hypoglycemia Samples from Patients with Type 1 Diabetes

Dana S. Hardin et al.

DIABETES THERAPY (2015)

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Article Endocrinology & Metabolism

Dogs Can Be Successfully Trained to Alert to Hypoglycemia Samples from Patients with Type 1 Diabetes

Dana S. Hardin et al.

DIABETES THERAPY (2015)

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Article Oncology

Assessment of ovarian cancer conditions from exhaled breath

Haitham Amal et al.

INTERNATIONAL JOURNAL OF CANCER (2015)

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Article Critical Care Medicine

Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD

Jing Zhang et al.

RESPIRATORY CARE (2015)

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Article Biochemical Research Methods

Established methodological issues in electronic nose research: how far are we from using these instruments in clinical settings of breath analysis?

Andras Bikov et al.

JOURNAL OF BREATH RESEARCH (2015)

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Review Biochemistry & Molecular Biology

Chemical aspects of hydrogen sulfide measurements in physiological samples

Peter Nagy et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)

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Letter Respiratory System

Detecting active pulmonary tuberculosis with a breath test using nanomaterial-based sensors

Morad K. Nalchleh et al.

EUROPEAN RESPIRATORY JOURNAL (2014)

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Article Oncology

Electronic nose can discriminate colorectal carcinoma and advanced adenomas by fecal volatile biomarker analysis: proof of principle study

Tim G. de Meij et al.

INTERNATIONAL JOURNAL OF CANCER (2014)

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Article Pathology

Combined sputum hypermethylation and eNose analysis for lung cancer diagnosis

A. Jasmijn Hubers et al.

JOURNAL OF CLINICAL PATHOLOGY (2014)

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Article Optics

Performance of a fire detector based on a compact laser spectroscopic carbon monoxide sensor

A. Hangauer et al.

OPTICS EXPRESS (2014)

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Article Multidisciplinary Sciences

Exhaled Breath Analysis Using Electronic Nose in Cystic Fibrosis and Primary Ciliary Dyskinesia Patients with Chronic Pulmonary Infections

Odin Joensen et al.

PLOS ONE (2014)

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Article Cardiac & Cardiovascular Systems

Identification of airway bacterial colonization by an electronic nose in Chronic Obstructive Pulmonary Disease

Oriol Sibila et al.

RESPIRATORY MEDICINE (2014)

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Article Respiratory System

Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma

Jing Zhang et al.

RESPIROLOGY (2014)

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Article Gastroenterology & Hepatology

Breath tests and irritable bowel syndrome

Satya Vati Rana et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

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Article Biochemical Research Methods

A practical approach to the theoretical models to calculate NO parameters of the respiratory system

M. Hogman et al.

JOURNAL OF BREATH RESEARCH (2014)

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Article Biochemical Research Methods

Current breathomics-a review on data pre-processing techniques and machine learning in metabolomics breath analysis

A. Smolinska et al.

JOURNAL OF BREATH RESEARCH (2014)

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Review Biochemical Research Methods

The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva

Anton Amann et al.

JOURNAL OF BREATH RESEARCH (2014)

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Article Respiratory System

Exhaled breath profiling for diagnosing acute respiratory distress syndrome

Lieuwe D. J. Bos et al.

BMC PULMONARY MEDICINE (2014)

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Article Respiratory System

Expiratory flow rate, breath hold and anatomic dead space influence electronic nose ability to detect lung cancer

Andras Bikov et al.

BMC PULMONARY MEDICINE (2014)

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Article Microbiology

Correction: Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome

Tsin W. Yeo et al.

PLoS Pathogens (2014)

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Article Otorhinolaryngology

Fractional exhaled nitric oxide (FeNo) in different asthma phenotypes

Bilun Gemicioglu et al.

ALLERGY & RHINOLOGY (2014)

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Letter Critical Care Medicine

A Proof of Concept for the Detection and Classification of Pulmonary Arterial Hypertension through Breath Analysis with a Sensor Array

Sylvia Cohen-Kaminsky et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

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Article Oncology

Cancer odor in the blood of ovarian cancer patients: a retrospective study of detection by dogs during treatment, 3 and 6 months afterward

Gyorgy Horvath et al.

BMC CANCER (2013)

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Article Allergy

Predicting steroid responsiveness in patients with asthma using exhaled breath profiling

M. P. van der Schee et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2013)

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Article Respiratory System

Exhaled nitric oxide decreases during exercise in non-asthmatic children

Bjorg Evjenth et al.

CLINICAL RESPIRATORY JOURNAL (2013)

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Review Respiratory System

Application of 'omics technologies to biomarker discovery in inflammatory lung diseases

Craig E. Wheelock et al.

EUROPEAN RESPIRATORY JOURNAL (2013)

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Letter Cardiac & Cardiovascular Systems

Single Exhaled Breath Metabolomic Analysis Identifies Unique Breathprint in Patients With Acute Decompensated Heart Failure

Michael A. Samara et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

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Review Biotechnology & Applied Microbiology

Nanomaterial-based sensors for detection of disease by volatile organic compounds

Yoav Y. Broza et al.

NANOMEDICINE (2013)

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Article Biotechnology & Applied Microbiology

Detection of Alzheimer's and Parkinson's disease from exhaled breath using nanomaterial-based sensors

Ulrike Tisch et al.

NANOMEDICINE (2013)

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Article Nanoscience & Nanotechnology

A nanomaterial-based breath test for short-term follow-up after lung tumor resection

Yoav Y. Broza et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2013)

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Article Multidisciplinary Sciences

Detection of an Extended Human Volatome with Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry

Michael Phillips et al.

PLOS ONE (2013)

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Article Biochemical Research Methods

Follow up of lung transplant recipients using an electronic nose

Dorottya Kovacs et al.

JOURNAL OF BREATH RESEARCH (2013)

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Article Biochemical Research Methods

Relationship between alveolar nitric oxide concentration in exhaled air and small airway function in COPD

Tsunahiko Hirano et al.

JOURNAL OF BREATH RESEARCH (2013)

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Review Biochemical Research Methods

The importance of methane breath testing: a review

B. P. J. de Lacy Costello et al.

JOURNAL OF BREATH RESEARCH (2013)

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Article Biochemical Research Methods

Methods of NO detection in exhaled breath

S. M. Cristescu et al.

JOURNAL OF BREATH RESEARCH (2013)

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Article Respiratory System

Standardised exhaled breath collection for the measurement of exhaled volatile organic compounds by proton transfer reaction mass spectrometry

Andras Bikov et al.

BMC PULMONARY MEDICINE (2013)

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Article Medicine, General & Internal

Exhaled nitric oxide and atherosclerosis

Iiris Salonen et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2012)

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Article Respiratory System

A breath test for malignant mesothelioma using an electronic nose

Eleanor A. Chapman et al.

EUROPEAN RESPIRATORY JOURNAL (2012)

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Article Biochemical Research Methods

Exhaled nitric oxide monitoring by quantum cascade laser: comparison with chemiluminescent and electrochemical sensors

Julien Mandon et al.

JOURNAL OF BIOMEDICAL OPTICS (2012)

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Article Cardiac & Cardiovascular Systems

Increased Exhaled Nitric Oxide Levels After Exercise in Patients With Chronic Systolic Heart Failure With Pulmonary Venous Hypertension

Andres Schuster et al.

JOURNAL OF CARDIAC FAILURE (2012)

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Article Oncology

An electronic nose distinguishes exhaled breath of patients with Malignant Pleural Mesothelioma from controls

Silvano Dragonieri et al.

LUNG CANCER (2012)

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Article Nanoscience & Nanotechnology

Classification of lung cancer histology by gold nanoparticle sensors

Orna Barash et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2012)

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Review Physiology

PHYSIOLOGICAL IMPLICATIONS OF HYDROGEN SULFIDE: A WHIFF EXPLORATION THAT BLOSSOMED

Rui Wang

PHYSIOLOGICAL REVIEWS (2012)

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Article Biochemistry & Molecular Biology

Detection of Multiple Sclerosis from Exhaled Breath Using Bilayers of Polycyclic Aromatic Hydrocarbons and Single-Wall Carbon Nanotubes

Radu Ionescu et al.

ACS CHEMICAL NEUROSCIENCE (2011)

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Letter Surgery

Exhaled Nitric Oxide in Diagnosis of Bronchiolitis Obliterans Syndrome in Lung Transplant Recipients: Possible Limitations

B. Antus et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2011)

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Article Biotechnology & Applied Microbiology

Exhaled breath volatile alterations in pregnancy assessed with electronic nose

Andras Bikov et al.

BIOMARKERS (2011)

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Article Physiology

Repeatability of exhaled nitric oxide measurements in patients with COPD

Annamari Rouhos et al.

CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING (2011)

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Review Allergy

A Meta-analysis of the Association of Exhaled Carbon Monoxide on Asthma and Allergic Rhinitis

Yu Shaoqing et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2011)

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Article Respiratory System

Assessment of Reproducibility of Exhaled Hydrogen Peroxide Concentration and the Effect of Breathing Pattern in Healthy Subjects

Reka Gajdocsi et al.

JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY (2011)

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Article Medicine, General & Internal

Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial

Heather Powell et al.

LANCET (2011)

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Article Multidisciplinary Sciences

Insect olfaction from model systems to disease control

Allison F. Carey et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Letter Respiratory System

Influence of respiratory variables on the on-line detection of exhaled trace gases by PTR-MS

Piers R. Boshier et al.

THORAX (2011)

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Review Biochemical Research Methods

Laser spectroscopy on volatile sulfur compounds: possibilities for breath analysis

L. Ciaffoni et al.

JOURNAL OF BREATH RESEARCH (2011)

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Article Psychology, Clinical

Tuberculosis Detection by Giant African Pouched Rats

Alan Poling et al.

BEHAVIOR ANALYST (2011)

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Article Chemistry, Analytical

Automated Needle Trap Heart-Cut GC/MS and Needle Trap Comprehensive Two-Dimensional GC/TOF-MS for Breath Gas Analysis in the Clinical Environment

Maren Mieth et al.

ANALYTICAL CHEMISTRY (2010)

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Article Pharmacology & Pharmacy

Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide

Christopher F. Toombs et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)

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Article Critical Care Medicine

Diagnostic Performance of an Electronic Nose, Fractional Exhaled Nitric Oxide, and Lung Function Testing in Asthma

Paolo Montuschi et al.

CHEST (2010)

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Article Oncology

An investigation on electronic nose diagnosis of lung cancer

Arnaldo D'Amico et al.

LUNG CANCER (2010)

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Article Cardiac & Cardiovascular Systems

Assessment of exhaled nitric oxide by a new hand-held device

Balazs Antus et al.

RESPIRATORY MEDICINE (2010)

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Review Chemistry, Analytical

Metal Oxide Sensors for Electronic Noses and Their Application to Food Analysis

Amalia Berna

SENSORS (2010)

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Article Biochemical Research Methods

Exhaled carbon monoxide in airway diseases: from research findings to clinical relevance

Reka Gajdocsy et al.

JOURNAL OF BREATH RESEARCH (2010)

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Article Respiratory System

Exhaled carbon monoxide in asthmatics: a meta-analysis

Jingying Zhang et al.

RESPIRATORY RESEARCH (2010)

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Article Biochemical Research Methods

Analysis of exhaled breath from smokers, passive smokers and non-smokers by solid-phase microextraction gas chromatography/mass spectrometry

Boguslaw Buszewski et al.

BIOMEDICAL CHROMATOGRAPHY (2009)

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Review Respiratory System

Exhaled biomarkers in lung cancer

I. Horvath et al.

EUROPEAN RESPIRATORY JOURNAL (2009)

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Article Allergy

Exhaled Nitric Oxide in Pregnant Healthy and Asthmatic Women

Lilla Tamási et al.

JOURNAL OF ASTHMA (2009)

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Article Respiratory System

Extended Nitric Oxide Measurements in Exhaled Air of Cystic Fibrosis and Healthy Adults

Markus Hofer et al.

LUNG (2009)

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Article Cardiac & Cardiovascular Systems

Exhaled breath condensate biomarkers in asbestos-related lung disorders

Sharron Chow et al.

RESPIRATORY MEDICINE (2009)

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Review Chemistry, Analytical

Breath Analysis Using Laser Spectroscopic Techniques: Breath Biomarkers, Spectral Fingerprints, and Detection Limits

Chuji Wang et al.

SENSORS (2009)

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Letter Respiratory System

Environmental temperature and relative humidity influence exhaled breath condensate pH

T. Kullmann et al.

EUROPEAN RESPIRATORY JOURNAL (2008)

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Article Cardiac & Cardiovascular Systems

Comparison of exhaled nitric oxide measurements between NIOX MINO® electrochemical and Ecomedics chemiluminescence analyzer

J. D. Boot et al.

RESPIRATORY MEDICINE (2008)

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Article Cardiac & Cardiovascular Systems

Influence of condensing equipment and temperature on exhaled breath condensate pH, total protein and leukotriene concentrations

Krisztina Czebe et al.

RESPIRATORY MEDICINE (2008)

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Article Biochemical Research Methods

Application of a quartz microbalance based gas sensor array for the study of halitosis

Giorgio Pennazza et al.

JOURNAL OF BREATH RESEARCH (2008)

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Article Biochemical Research Methods

A sensor system for monitoring the simple gases hydrogen, carbon monoxide, hydrogen sulfide, ammonia and ethanol in exhaled breath

B. P. J. de Lacy Costello et al.

JOURNAL OF BREATH RESEARCH (2008)

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Article Biochemical Research Methods

A study of sulfur-containing compounds in mouth- and nose-exhaled breath and in the oral cavity using selected ion flow tube mass spectrometry

A. Pysanenko et al.

JOURNAL OF BREATH RESEARCH (2008)

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Article Allergy

An electronic nose in the discrimination of patients with asthma and controls

Silvano Dragonieri et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)

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Article Biochemical Research Methods

Performance of an exhaled nitric oxide and carbon dioxide sensor using quantum cascade laser-based integrated cavity output spectroscopy

Matthew R. McCurdy et al.

JOURNAL OF BIOMEDICAL OPTICS (2007)

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Article Gastroenterology & Hepatology

Hydrogen sulfide, nitric oxide and a molecular mass 66 u substance in the exhaled breath of chronic pancreatitis patients

Antonio M. Morselli-Labate et al.

PANCREATOLOGY (2007)

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Article Respiratory System

Nitric oxide and exhaled breath nitrite/nitrates in chronic obstructive pulmonary disease patients

Jia Liu et al.

RESPIRATION (2007)

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Article Physiology

Determination of ethane, pentane and isoprene in exhaled air - effects of breath-holding, flow rate and purified air

M. A. E. Larstad et al.

ACTA PHYSIOLOGICA (2007)

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Article Respiratory System

Effect of smoking on exhaled nitric oxide and flow-independent nitric oxide exchange parameters

A. Malinovschi et al.

EUROPEAN RESPIRATORY JOURNAL (2006)

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Review Chemistry, Analytical

Metal oxide nano-crystals for gas sensing

Elisabetta Comini

ANALYTICA CHIMICA ACTA (2006)

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Article Respiratory System

Fractional exhaled nitric oxide concentration is increased in asbestosis and pleural plaques

A Sandrini et al.

RESPIROLOGY (2006)

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Article Respiratory System

Volatile organic compounds in the exhaled breath of young patients with cystic fibrosis

M Barker et al.

EUROPEAN RESPIRATORY JOURNAL (2006)

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Article Respiratory System

Performance of a new hand-held device for exhaled nitric oxide measurement in adults and children

K Alving et al.

RESPIRATORY RESEARCH (2006)

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Article Respiratory System

Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study

D Poli et al.

RESPIRATORY RESEARCH (2005)

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Article Respiratory System

Exhaled nitric oxide from lung periphery is increased in COPD

C Brindicci et al.

EUROPEAN RESPIRATORY JOURNAL (2005)

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Article Critical Care Medicine

Detection of lung cancer by sensor array analyses of exhaled breath

RF Machado et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

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Article Surgery

Pulmonary infections increase exhaled nitric oxide in lung transplant recipients: a longitudinal study

B Antus et al.

CLINICAL TRANSPLANTATION (2005)

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Article Critical Care Medicine

ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005

American Thoracic Society et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

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Review Respiratory System

Exhaled breath condensate: methodological recommendations and unresolved questions

I Horvath et al.

EUROPEAN RESPIRATORY JOURNAL (2005)

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Review Physiology

Modeling pulmonary nitric oxide exchange

SC George et al.

JOURNAL OF APPLIED PHYSIOLOGY (2004)

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Review Chemistry, Multidisciplinary

Comparisons between mammalian and artificial olfaction based on arrays of carbon black-polymer composite vapor detectors

NS Lewis

ACCOUNTS OF CHEMICAL RESEARCH (2004)

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Article Engineering, Environmental

Monitoring of biological odour filtration in closed environments with olfactometry and an electronic nose

H Willers et al.

WATER SCIENCE AND TECHNOLOGY (2004)

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Article Respiratory System

Exhaled nitric oxide and hydrogen peroxide concentrations in asthmatic smokers

I Horvath et al.

RESPIRATION (2004)

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Article Environmental Sciences

Possible association between passive smoking and lower exhaled nitric oxide in asthmatic children

TJ Warke et al.

ARCHIVES OF ENVIRONMENTAL HEALTH (2003)

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Article Biophysics

Lung cancer identification by the analysis of breath by means of an array of non-selective gas sensors

C Di Natale et al.

BIOSENSORS & BIOELECTRONICS (2003)

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Article Biochemistry & Molecular Biology

A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics

TT Hansel et al.

FASEB JOURNAL (2003)

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Article Nutrition & Dietetics

Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality

RJ Nijveldt et al.

CLINICAL NUTRITION (2003)

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Article Respiratory System

Comparison of exhaled and nasal nitric oxide and exhaled carbon monoxide levels in bronchiectatic patients with and without primary ciliary dyskinesia

I Horvath et al.

THORAX (2003)

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Article Critical Care Medicine

Passive smoke inhalation decreases exhaled nitric oxide in normal subjects

DH Yates et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)

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Article Chemistry, Analytical

Detection and classification characteristics of arrays of carbon black/organic polymer composite chemiresistive vapor detectors for the nerve agent simulants dimethylmethylphosphonate and diisopropylmethylphosponate

AR Hopkins et al.

ANALYTICAL CHEMISTRY (2001)

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Review Biochemistry & Molecular Biology

Hydrogen peroxide in the human body

B Halliwell et al.

FEBS LETTERS (2000)

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Article Critical Care Medicine

Production of endogenous nitric oxide in chronic obstructive pulmonary disease and patients with cor pulmonale - Correlates with echo-doppler assessment

E Clini et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)

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Article Critical Care Medicine

Exhaled nitric oxide and exercise in stable COPD patients

E Clini et al.

CHEST (2000)

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Article Chemistry, Analytical

An investigation of the concentration dependence and response to analyte mixtures of carbon black/insulating organic polymer composite vapor detectors

EJ Severin et al.

ANALYTICAL CHEMISTRY (2000)

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