☆ 4.6 Article

P53 maintains gallid alpha herpesvirus 1 replication by direct regulation of nucleotide metabolism and ATP synthesis through its target genes

FRONTIERS IN MICROBIOLOGY (2022)

Related references

Note: Only part of the references are listed.

Article Microbiology

PFT-? inhibits gallid alpha herpesvirus 1 replication by repressing host nucleotide metabolism and ATP synthesis

Li Xu et al.

Summary: This study discovered that the small molecule PFT-alpha has antiviral activity against avian infectious laryngotracheitis virus (ILTV) by suppressing viral transcription and genome replication. The study further revealed that PFT-alpha inhibits ILTV replication by targeting host nucleotide metabolism and ATP synthesis.

VETERINARY MICROBIOLOGY (2022)

Add to Collection

Article Agriculture, Dairy & Animal Science

Characterization of chicken p53 transcriptional function via parallel genome- wide chromatin occupancy and gene expression analysis

Zhijie Chen et al.

Summary: In this study, the chp53 transcriptional regulatory network was comprehensively characterized through analysis of chromatin occupancy and gene expression, providing insights into the underlying mechanisms of chp53's antiviral functions in chickens. The findings also contribute to a better understanding of p53 transcriptional regulatory mechanisms.

POULTRY SCIENCE (2022)

Add to Collection

Article Gastroenterology & Hepatology

Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus

Shushu Song et al.

Summary: Dysfunction of ER proteins is closely related to HCC development. RTN3 is expressed in normal hepatocytes but downregulated in HCC, predicting poor outcomes in patients with certain gene mutations or infections. RTN3 functions as a suppressor of HCC by activating the Chk2/p53 pathway, but its effects are abrogated in HBV-positive cells.

GUT (2021)

Add to Collection

Article Agriculture, Dairy & Animal Science

IMMUNOLOGY, HEALTH AND DISEASE Knockout of p53 leads to a significant increase in ALV-J replication

Hui Zhang et al.

Summary: The study successfully constructed a p53 knockout DF-1 cell line using the CRISPR-Cas9 system and found that the p53 gene can effectively inhibit ALV-J replication by regulating important cellular processes. Proteins related to the p53 gene involved in cell cycle activity may serve as key targets for the prevention and treatment of ALV-J.

POULTRY SCIENCE (2021)

Add to Collection

Article Virology

Coronavirus Porcine Epidemic Diarrhea Virus Nucleocapsid Protein Interacts with p53 To Induce Cell Cycle Arrest in S-Phase and Promotes Viral Replication

Mingjun Su et al.

Summary: The study revealed that PEDV N protein interacts with p53 to activate the p53-DREAM pathway, inducing S-phase arrest to promote viral replication. Hyperoside, a small molecular compound, can antagonize N protein-induced S-phase arrest and inhibit viral replication by interfering with N protein-p53 interaction. These findings shed new light on PEDV-host interaction and offer a novel antiviral strategy against PEDV.

JOURNAL OF VIROLOGY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence

Jessica C. Garbern et al.

CIRCULATION (2020)

Add to Collection

Article Virology

Reactivation of Epstein-Barr Virus by HIF-1α Requires p53

Richard J. Kraus et al.

JOURNAL OF VIROLOGY (2020)

Add to Collection

Article Microbiology

Global exploration of the metabolic requirements of gallid alphaherpesvirus 1

Yangyang Qiao et al.

PLOS PATHOGENS (2020)

Add to Collection

Article Microbiology

p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication

Xin Wang et al.

PLOS PATHOGENS (2020)

Add to Collection

Article Immunology

Superinfection and recombination of infectious laryngotracheitis virus vaccines in the natural host

Omid Fakhri et al.

VACCINE (2020)

Add to Collection

Article Multidisciplinary Sciences

Attenuated infectious laryngotracheitis virus vaccines differ in their capacity to establish latency in the trigeminal ganglia of specific pathogen free chickens following eye drop inoculation

Dulari S. Thilakarathne et al.

PLOS ONE (2019)

Add to Collection

Article Multidisciplinary Sciences

Glycoprotein G (gG) production profile during infectious laryngotracheitis virus (ILTV) infection

Jorge Bendezu et al.

PLOS ONE (2019)

Add to Collection

Review Veterinary Sciences

Commercial Vaccines and Vaccination Strategies Against Infectious Laryngotracheitis: What We Have Learned and Knowledge Gaps That Remain

Maricarmen Garcia et al.

AVIAN DISEASES (2019)

Add to Collection

Article Virology

Gallid Herpesvirus 1 Initiates Apoptosis in Uninfected Cells through Paracrine Repression of p53

Hai Li et al.

JOURNAL OF VIROLOGY (2018)

Add to Collection

Review Biochemistry & Molecular Biology

Heroesviruses anc Their Host Cells: A Successful Liaison

Barbara Adler et al.

TRENDS IN MICROBIOLOGY (2017)

Add to Collection

Article Microbiology

gga-miR-2127 downregulates the translation of chicken p53 and attenuates chp53-mediated innate immune response against IBDV infection

Wei Ouyang et al.

VETERINARY MICROBIOLOGY (2017)

Add to Collection

Article Oncology

P53 suppresses ribonucleotide reductase via inhibiting mTORC1

Zhengfu He et al.

ONCOTARGET (2017)

Add to Collection

Review Biochemistry & Molecular Biology

Putting p53 in Context

Edward R. Kastenhuber et al.

CELL (2017)

Add to Collection

Article Pathology

Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer

Kerstin Holzer et al.

AMERICAN JOURNAL OF PATHOLOGY (2017)

Add to Collection

Article Pathology

Mutations in and Expression of the Tumor Suppressor Gene p53 in Egg-Type Chickens Infected With Subgroup J Avian Leukosis Virus

Q. Yue et al.

VETERINARY PATHOLOGY (2015)

Add to Collection

Article Fisheries

Immune responses to infectious laryngotracheitis virus

Mauricio J. C. Coppo et al.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Gadd45a Suppresses Tumor Angiogenesis via Inhibition of the mTOR/STAT3 Protein Pathway

Fang Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Add to Collection

Article Multidisciplinary Sciences

Complete Genome Sequence of the First Chinese Virulent Infectious Laryngotracheitis Virus

Congcong Kong et al.

PLOS ONE (2013)

Add to Collection

Article Immunology

Kinetics of transcription of infectious laryngotracheitis virus genes

Alireza Mahmoudian et al.

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES (2012)

Add to Collection

Article Multidisciplinary Sciences

Attenuated Vaccines Can Recombine to Form Virulent Field Viruses

Sang-Won Lee et al.

SCIENCE (2012)

Add to Collection

Review Genetics & Heredity

Metabolic regulation by p53

Oliver D. K. Maddocks et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2011)

Add to Collection

Article Virology

The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities

Xufang Deng et al.

VIROLOGY JOURNAL (2010)

Add to Collection

Article Biochemical Research Methods

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Da Wei Huang et al.

NATURE PROTOCOLS (2009)

Add to Collection

Review Oncology

The expanding universe of p53 targets

Daniel Menendez et al.

NATURE REVIEWS CANCER (2009)

Add to Collection

Article Veterinary Sciences

Replication and Transmission of Live Attenuated Infectious Laryngotracheitis Virus (ILTV) Vaccines

Andres Rodriguez-Avila et al.

AVIAN DISEASES (2007)

Add to Collection

© Peeref 2019-2024. All rights reserved.